Identification of a previously unknown mechanism controlling the interaction between astrocytes and blood vessels in the brain

Moises Freitas-Andrade and Baptiste Lacoste

Moises Freitas-Andrade, Baptiste Lacoste

Title of publication : Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.

First author : Dr. Moises Freitas-Andrade

A new publication from Dr. Baptiste Lacoste’s laboratory at University of Ottawa identifies a previously unknown mechanism controlling the interaction between astrocytes and blood vessels in the brain.

Serving as bridges between neurons and blood vessels in the brain, astrocytes (a type of glial cells) send specialized extensions or ‘endfeet’ around blood vessels to help shape these vessels during development and later control cerebral blood flow (CBF). Astrocytes belong to the ‘neurovascular unit’ (NVU), a multi-cellular ensemble serving as a hub for neurovascular interactions. Despite a wealth of knowledge on astrocytes, and while we know these cells become mature after birth, little is known about the mechanisms driving their recruitment around brain blood vessels, or about their contribution to blood vessel maturation.

In this study, Dr. Lacoste’s team addresses these knowledge gaps not only by thoroughly characterizing the time course of astrocyte-blood vessel interactions in the early postnatal mouse brain, but also by assessing gene expression changes in astrocytes during that period. Doing so, the researchers identify an important molecular player produced by astrocytes, namely HMGB1, which controls their morphology, their placement around blood vessels, and the maturation of NVU.

Using genetic tools to block the production of HMGB1 protein selectively in astrocytes early after birth, Dr. Lacoste’s team shows that HMGB1 controls astrocyte morphogenesis and the maturation of endfeet around blood vessels. Lack of HMGB1 in astrocytes at birth impaired blood vessel maturation and resulted in surprising alterations of behavior in adult mice, that displayed an anxiety-like phenotype.

This study thus identifies a previously unknown mechanism controlling the interaction between astrocytes and blood vessels in the brain, helping scientists to better understand postnatal brain development and the contribution of non-neuronal cells to this process.

Publication: Freitas-Andrade, M., Comin, C.H., Van Dyken, P. et al. Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation. Nat Commun 14, 4965 (2023).

Tenure-Track Appointment in Neurorehabilitation – Simon Fraser University

Department of Biomedical Physiology and Kinesiology, Faculty of Science
Last updated August 2, 2023

The Opportunity

The Department of Biomedical Physiology and Kinesiology (BPK) invites applications for a tenure track faculty position at the rank of Assistant Professor in Neurorehabilitation to commence July 1, 2024, or a mutually agreed-upon date.

Desired research area

The ideal candidate will lead a research program on neurorehabilitation and recovery of function following disease, trauma, or age-related impairment with an emphasis on translational research using animal and/or human models. Areas may include but are not limited to the control of movement, sensory plasticity, autonomic regulation, cognitive rehabilitation, and/or developing assistive technologies. Through their research, the ideal candidate will participate in the newly established Institute for Neuroscience and Neurotechnology, as well as in technology innovation and entrepreneurship initiatives at SFU. The candidate will have a collaborative disposition and sufficiently broad interests and expertise to readily engage in collaborations with other researchers in BPK, SFU, and the broader neuroscience community.

Core duties of the Assistant Professor in Neurorehabilitation:

  • Research: Develop an externally funded research program devoted to advancing the field of neurorehabilitation, supervise and mentor graduate students and other highly qualified personnel, and disseminate discoveries through peer-reviewed publications, conference presentations, and other forums appropriate to the discipline.
  • Teaching: Teach undergraduate and graduate courses in the areas of neurorehabilitation and neuroscience, and contribute to curriculum and program development.
  • Service: Serve the Department, the University, and the larger scientific community, by contributing to committee work and in departmental initiatives.

The typical workload distribution for assistant professors in BPK is 40% research, 40% teaching, and 20% service. In carrying out these duties, the successful candidate will advance BPK’s goals to foster equity, diversity, and inclusion; for example, by working to eliminate the barriers that impede the ability of department members from historically underrepresented and marginalized populations to achieve their full potential. The successful candidate will foster a positive and inclusive working environment through respectful interactions with all faculty, staff, and students. The responsibilities, terms, and conditions of employment of faculty are listed in the SFU-SFUFA collective agreement.

About the Department and University

About the Department of Biomedical Physiology and Kinesiology (BPK)
The mission of BPK is to advance the understanding of physiology, movement, neuroscience, and human health through fundamental and applied research, education, and service. BPK offers undergraduate degrees (BSc, BSc Honours) in kinesiology, biomedical physiology, and behavioural neuroscience, as well as graduate degrees (MSc, PhD). BPK is part of the Translational and Integrative Neuroscience (TRAIN) Graduate Specialization. The Department includes 24 research faculty, 9 continuing teaching faculty members, 7.4 staff members, approximately 50 graduate students, and over 1,000 undergraduate majors. BPK features research clusters in exercise and environmental physiology, cardiovascular physiology, chronic diseases, neuromechanics, and neuroscience.

About SFU

At the intersection of innovative education, cutting-edge research, and community engagement lies Simon Fraser University (SFU), Canada’s top-ranked comprehensive university. With three campuses located in beautiful British Columbia’s largest municipalities – Vancouver, Burnaby, and Surrey – our students, faculty, and staff are privileged to live and work on the traditional unceded territories of the xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh Úxwumixw (Squamish), səl̓ilw̓ətaʔɬ (Tsleil-Waututh), q̓íc̓əy̓ (Katzie), kʷikʷəƛ̓əm (Kwikwetlem), Qayqayt, Kwantlen, Semiahmoo, and Tsawwassen Peoples. Consistently ranked as one of Canada’s top employers, SFU’s excellence as an engaged university is derived from our shared commitments to diversity, equity, and inclusion, and the pursuit of decolonization, indigenization, and reconciliation.

SFU offers several unique assets to its research faculty that are particularly relevant to this position. This includes the newly established Institute for Neuroscience and Neurotechnology. SFU also hosts several core facilities, including the ImageTech Lab, which is embedded at Surrey Memorial Hospital and houses state-of-the-art MRI and MEG equipment, and eBrain Lab, which focuses on neuro-engineering solutions for mental health and addiction. Other relevant facilities include the recently opened core facility for wearable technologies (WearTech Labs), the Big Data Hub, 4D Labs for materials research and development, and a state-of-the-art animal research facility. SFU supports research translation through the SFU Knowledge Mobilization Initiative and innovation through SFU Innovates. As a testament to BPK and SFU’s culture of innovation, BPK professors have founded four companies in the past 20 years, while World University Rankings for Innovation 2023 ranked SFU second globally in the Entrepreneurial Spirit category and 13th globally in the Innovative Universities category. Metro Vancouver offers burgeoning wearable technology and biomedical device ecosystems, with several start-up and mid-sized companies now operating who are keen to engage in academic-industry partnerships. Several BPK faculty who conduct clinical research maintain affiliations with local hospitals including the BC Children’s -, Surrey Memorial -, Vancouver General -, and Royal Columbian Hospitals.

The Successful Candidate

The following credentials, skills, expertise, experience, values, and attitudes comprise the desired qualifications.

The successful candidate must:

  • Hold a PhD, MD, or equivalent degree in neuroscience, rehabilitation sciences, kinesiology, biomedical engineering, or a related discipline.
  • Have at least one year of postdoctoral or related research experience.
  • Have demonstrated excellence in research in neurorehabilitation. Excellence will be assessed in various ways, including but not limited to the following criteria:
  • Extensive experience conducting scientific studies in neurorehabilitation
  • High-quality scientific publications in the leading peer-reviewed journals of the field
  • Awards or external funding (e.g., scholarships)
  • Disseminated discoveries via conferences, seminars, and other mechanisms for knowledge translation
  • Articulate a compelling vision for a research program that addresses questions of fundamental importance to the field and has clear potential to attract top-quality trainees, external funding, new scientific collaborations, and uptake by knowledge users.
  • Show clear potential for excellence as a mentor of research trainees, especially those from equity-deserving groups.
  • Demonstrate deep and broad knowledge of the fields of neuroscience and neurorehabilitation to teach undergraduate and graduate courses effectively in these areas.
  • Show strong potential for effective teaching of undergraduate courses and fostering of inclusive learning environments.
  • Show strong potential for effective knowledge translation and community engagement.
  • Suggest potential research collaborations in the Department.
  • Demonstrate outstanding interpersonal and communication skills (oral and written, in English). These skills include but are not limited to strong listening skills, valuing and respecting diverse perspectives, and a collaborative disposition.
  • Show strong potential to be an engaged academic citizen, in part by demonstrating a record of volunteerism and participation in service activities, such as committee work and outreach initiatives.

The following qualifications are considered assets:

  • A degree in physical or occupational therapy.
  • Interest and capability for running both animal and human research experiments to foster translation.
  • Experience conducting research in diverse environments or from different perspectives.
  • Show clear potential to collaborate within and outside the University.
  • Previous or existing collaborations with leading researchers.
  • Have assisted or led the teaching of undergraduate courses, and in so doing demonstrated keen interest in teaching, strong pedagogical skills, and effectiveness in fostering inclusive learning environments.
  • Demonstrated experience in increasing diversity in their previous institutional environment(s) or in curricula.
  • Experience or goals to apply research to better understand and address health issues affecting underrepresented populations.
  • Interest, experience, and expertise in entrepreneurship and technology development.
  • Leadership potential, demonstrated by leadership roles, formal leadership training, or leadership abilities.

How To Apply
Candidates should address their applications to Dr. Dan Marigold (he/him/his), Chair of the Search Committee. Applications should consist of a single PDF file inclusive of and bookmarked for the following components:

  •  A cover letter (maximum two pages) that addresses: 1) reasons for applying to the position, and 2) a narrative description highlighting evidence that the candidate meets the job qualifications and can effectively perform the listed job duties.
  • A complete up-to-date curriculum vitae that lists the candidate’s education and employment history, publications and conference presentations, funding and awards, student supervision, collaborations/partnerships, teaching experience, and service activities.
  • A research statement (maximum two pages) that describes the candidate’s research experience, goals, and a five-year plan for their research program.
  • Three examples of peer-reviewed published scholarly work.
  • A teaching statement (maximum one page) that describes the candidate’s teaching philosophy, teaching experience, and evidence of teaching effectiveness.
  • A statement (maximum one page) describing past or potential contributions to enhancing equity, diversity, and inclusion within research, service, and teaching. Regarding the latter component, candidates should discuss their experience with and/or understanding of inclusive teaching and mentoring, and how the candidate would meet the needs of equity deserving students.
  • The names, titles, and email addresses of 3 or 4 referees who are qualified to assess the candidate’s research capabilities, at least one of whom can assess teaching potential. Referees will be contacted by SFU for candidates advancing to the later stages of the selection process.
  • Please indicate your legal status to work in Canada.

Candidates should submit their applications by email to with the subject line neurorehab2023__. Full consideration will be given to applications received by September 15, 2023. Applications received after this deadline may be reviewed if the position is still open.

SFU recognizes that alternative career paths and/or career interruptions (e.g., parental leave, leave due to illness) can impact research achievements and commits to ensuring that leaves are taken into careful consideration. Candidates are encouraged to highlight in their application how alternative paths and/or interruptions have impacted them. SFU also recognizes the value of mentoring and research training, outreach, professional service, and non-traditional areas of research and/or research outputs.

Simon Fraser University is an institution whose strength is based on our shared commitments to diversity, equity, and inclusion. Diversity is an underlying principle of our Strategic Vision, which pledges SFU to “foster a culture of inclusion and mutual respect, celebrating the diversity reflected among its students, faculty, staff, and our community.” SFU is committed to ensuring that no individual is denied access to employment opportunities for reasons unrelated to ability or qualifications. Consistent with this principle, SFU will advance the interests of underrepresented members of the work force, including Indigenous peoples, persons with disabilities, racialized persons, and women; embrace gender and sexual diversity; ensure that equal opportunity is afforded to all who seek employment at the University; and treat all employees equitably. Candidates that belong to underrepresented groups are particularly encouraged to apply.

SFU offers several benefits and services aimed at creating a more inclusive and accessible campus community for faculty; please see the Faculty Relations, Benefits and Service page for more details. SFU is also committed to ensuring that the application and interview process is accessible to all applicants. If you require accommodations or have questions about SFU benefits, services, accommodations policies, or equity considerations, please contact the Specialist, Equity, Diversity and Inclusion in Faculty Relations.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority. Under the authority of the University Act, personal information that is required by the University for academic appointment competitions will be collected. For further details, refer to the Collection Notice.

The position is subject to availability of funding and approval by the SFU Board of Governors.

Inquiries regarding this posting may be directed to the BPK Chair’s Assistant,

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Assistant Professor, Molecular and Cellular Biology

Faculty Positions
Position Title / Rank: Assistant Professor in Molecular and Cellular Biology
College: College of Biological Science
Department: Molecular and Cellular Biology
Date Posted: July 13, 2023
Deadline: September 14, 2023
Please reference AD #23-41

The Department of Molecular and Cellular Biology at the University of Guelph invites applications from Black scholars for a tenure-track position at the rank of Assistant Professor. We are seeking outstanding candidates whose research interests will complement existing strengths in the Department. The successful applicant is expected to establish an innovative and sustainable research program that will integrate with and expand the Department’s research strengths and offer new avenues for collaboration. We are particularly interested in candidates with research expertise in the following areas, especially those that bridge more than one:

  • Biochemistry and biochemical approaches, including enzymology, structural biology, membrane and nucleic acid biochemistry, enzymology, biophysics or other methods.
  • Molecular and cellular biology, including signal transduction, membrane-less organelles, or RNA biology using research models that include invertebrates, vertebrates, immortalized cell lines, or patient-derived stem cells focusing on biomedical applications.
  • Microbiology, immunology and virology, including host-pathogen interactions, immune response mechanisms, microbiome analysis, antimicrobial resistance and vaccine development for viral, fungal and bacterial pathogens.
  • Plant biology, synthetic biology and biotechnology, including engineering of metabolic pathways, genomics and computational biology, genetic circuit design, and plant/microbial interactions to enhance plant productivity.
  • Genetics, including epigenetic mechanisms, genomics and bioinformatics, molecular genetics, g ene regulation, and genetic diseases in plants, animals, and microbial systems.
  • Neuroscience, including neurobiology, neurophysiology, neurodevelopment, synaptic plasticity, neuroimmunology, and the study of brain disorders using cellular and animal models.

Qualifications include a Ph.D., a preferred minimum of three years of relevant postdoctoral experience, a proven record of research excellence evident in high-quality publications and demonstrated potential to establish a competitive independent research program and secure external research funding. The successful candidate will join a dynamic, multidisciplinary, research-intensive department with 40 faculty members who study diverse biological systems at levels from molecules to cells that include Biochemistry, Microbiology, Molecular Biology & Genetics, and Neuroscience and contributes to programs in Biological Science, Biomedical Science, and Plant Science. Faculty within the College of Biological Science are members of the Advanced Analysis Centre, which houses state-of-the-art equipment that include facilities for solution- and solid-state NMR spectroscopy, mass spectrometry, electron and confocal microscopy, and genomics. Graduate student training activities are focused on M.Sc. and Ph.D. degrees in Molecular and Cellular Biology, and faculty members also participate in programs such as Biotechnology, Biophysics, Bioinformatics, Neuroscience, Plant Science, and Toxicology.

Applicants must also demonstrate a commitment to effective and innovative teaching at the undergraduate and graduate levels. The successful candidate will teach courses or parts of courses in the Department of Molecular and Cellular Biology to a diverse population of undergraduate and graduate students. At the University of Guelph, fostering a culture of inclusion (, critical thinking, solving complex problems, and creating a modern academic community. The willingness to work collaboratively with faculty and mentor students from various disciplines, cultures, and educational backgrounds is essential. The Department is a collegial, inclusive, and welcoming environment that values diversity and wellness among our members as key ingredients in our collective success. Therefore, the University invites and encourages applications from all qualified individuals, including groups traditionally underrepresented in employment, who may contribute to the further diver sification of our Institution.

This tenure-track faculty position is part of the University of Guelph’s Black and Indigenous Hiring Initiative. Launched in June 2022, the Black and Indigenous Hiring Initiative (BIHI) calls for hiring fifteen or more Black and Indigenous faculty and four or more Black and Indigenous professional staff across the University of Guelph during the next three years. The faculty and staff positions will be filled in areas that support the advancement of Black and Indigenous academic excellence and the University of Guelph’s commitments to inclusion, anti-racism, indigenization and decolonization.

The University of Guelph and the Department of Molecular and Cellular Biology seek qualified individuals who identify as persons of Black African or Caribbean descent. Applicants will be asked to self-identify through the Applicant Tracking Questionnaire (ATQ) facilitated by Diversity and Human Rights. We acknowledge the burden often placed on Black and Indigenous faculty regarding Indigenization, Equity, Diversity, and Inclusion in workplaces and the challenges inherent to engaging in work that runs counter to entrenched paradigms. We also acknowledge how holding non-traditional research programs, conducting community-engaged research, holding traditional knowledge, community relationships, etc., can adversely impact researchers with respect to conventional measures of academic excellence.

The University of Guelph is the third largest employer in Guelph, a city of approximately 130,000 people, located about an hour drive west of Toronto, Ontario. University of Guelph is a top-ranked comprehensive university in Canada with an enrolment of over 30,000 undergraduate and graduate students across over 40 academic units. The University is known for its commitment to student learning, innovative research, and collaboration with world-class partners. It is a unique place, with transformative research and teaching and a distinctive campus culture. People who learn and work here are shaped and inspired by a shared purpose: To Improve Life. Reflecting that shared purpose in every experience connected to our university positions us to create positive change, here and around the world. Our university community shares a profound sense of social responsibility, a drive for international development, and an obligation to address global issues.

Application Process

Assessment of applications will begin on September 14, 2023 and will continue until the position is filled. Interested candidates should submit the following materials as a single PDF file: (1) a cover letter indicating area(s) of research focus; (2) a curriculum vitae; (3) an overview of the proposed research program (max. 1500 words; see below for additional details); (4) a teaching statement (max. 500 words); (5) a separate statement describing the strategies you will use to promote inclusion and support a diverse community in your research lab and classrooms (max. 500 words); and (6) contact information of three references.

Applications should be sent by email to the attention of:

Dr. Cezar Khursigara

Professor and Department Chair

Molecular and Cellular Biology

College of Biological Science

University of Guelph

Guelph, ON N1G 2W1

The overview of the proposed research statement should be a maximum length of two pages. This statement should:

  • Detail the candidate’s specific area of expertise, describing their contributions to the field.
  • Please provide a detailed plan of their future independent research program and how this program might be leveraged to obtain extramural funding.
  • Indicate how the candidate’s research program will synergize with the Department’s research environment.

All qualified applicants are encouraged to apply; however, Canadians and permanent residents will be given priority.

The University recognizes that applicants may have had obligations outside of work that have negatively impacted their record of achievements (e.g., parental, elder care, and/or medical). You are not required to disclose these obligations in the hiring process. If you choose to do so, the University will ensure that these obligations do not negatively impact the assessment of your qualifications for the position.

The University of Guelph resides on the ancestral lands of the Attawandaron people and the treaty lands and territory of the Mississaugas of the Credit and we offer our respect to our Anishinaabe, Haudenosaunee and Métis neighbours as we strive to strengthen our relationships with them.

At the University of Guelph, fostering a culture of inclusion ( is an institutional imperative. The University invites and encourages applications from all qualified individuals, including from groups that are traditionally underrepresented in employment, who may contribute to further diversification of our Institution.

If you require a medical accommodation during the recruitment or selection process, please contact Occupational Health and Wellness at 519-824-4120 x52674.


ThinkSci Outreach Program wins a CAN Advocacy Award

The Canadian Association for Neuroscience is proud to announce its support of the ThinkSci Outreach Program with a 2023 CAN Advocacy and Outreach award.

The “ThinkSci Outreach Program” is a workshop-based initiative organized and led by undergraduate and graduate students, with the goal of immersing high school seniors and 1st year CÉGEP students into the world of neurophysiology. Its long term goal is to reach local, regional and national underrepresented student communities in Canada. Continue reading

Investing in science will benefit all Canadians.

CAN is sharing with you the brief we have submitted to the House of Commons Finance (FINA), which is currently holding its consultations in advance of federal budget 2024. – our three recommendations are

The Canadian Association for Neuroscience recommends the following:

Recommendation 1: That the government double the budgets of the three main federal funding agencies: Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC) and the Social Sciences and Humanities Research Council (SSHRC) for the benefit of all Canadians. This recommendation aims to bring Canadian investment in scientific research to a level commensurate to that of other G7 countries.

Recommendation 2: That the government of Canada double support for graduate students and postdoctoral fellows by increasing both the value and number of fellowships awarded in the next budget. In conjunction with Recommendation 1, this recommendation will ensure our next generation of scientists have the means to participate fully in Canada’s knowledge economy.

Recommendation 3: That the government of Canada make research on the Brain and Mental Health a national priority by investing in research to understand the brain through well-established and trusted organizations in the field.

Read our full submission for the FINA pre-budget submission here: Continue reading

Earl Russell Chair in Pain Management – Schulich School of Medicine & Dentistry, Western University

Position Profile:

The Schulich School of Medicine & Dentistry, at Western University, is inviting applications for the position of Earl Russell Chair in Pain Management. The successful candidate will take a leadership role as the Earl Russell Chair in Pain Management through their research program. Applicants should have: 1) familiarity with, and deep commitment to the treatment of pain 2) experience and expertise in working in an interdisciplinary setting 3) leadership skills and experience in creating an effective team to study pain, 4) well developed teaching and interpersonal skills, and 5) an accomplished research track-record in pain. The successful candidate will be appointed in the department that most appropriately fits their expertise with a potential cross appointment in a relevant basic science department.

Academic and Clinical Expectations:

The candidate will have protected research time within the appointed department. Clinicians who have a devoted research commitment to studying pain, and fellowship training or clinical experience with treating pain patients, are encouraged to apply. Clinical duties and expectations to be determined by the clinical academic department.


The ideal candidate will have an MD or equivalent degree and will hold or be appointed at the rank of Associate or Full Professor with continuing (Clinical Academic) appointment, depending on qualifications and experience. The successful candidate will have completed a residency from the Royal College of Physicians and Surgeons of Canada or equivalent and fellowship training in a field related to pain medicine. The candidate should have or be eligible for registration by the College of Physicians and Surgeons of Ontario and should have or be eligible to attain active hospital privileges at London Health Sciences Centre and/or St. Joseph’s Health Care London.

Compensation Details:

The Chair appointment is for a five-year period, with the possibility of renewal for one additional term pending review recommendation. Compensation will be based on qualifications and experience and will be composed primarily of the following sources: fee for service, alternative funding plan and academic support.

The City:

London, Ontario is Canada’s 10th largest city with a population of 400,000, a catchment area of 2.4 million, and is situated in southwestern Ontario between Toronto and Detroit. The region has a strong economy and excellent primary and secondary school systems for residents with children. It is a safe and culturally diverse city. With parks, tree-lined streets and bicycle trails, London is known as the “Forest City”. London boasts an international airport, galleries, theatre, music, and sporting events. See to learn more.

The University:

Western University is a research-intensive university with full-time enrolment of 34,000 students and a full range of academic and professional programs. The Schulich School of Medicine & Dentistry provides an outstanding educational experience within a research-intensive environment where tomorrow’s physicians, dentists and health researchers learn to be socially responsible leaders in the advancement of human health. Western has extensive strengths in neuroscience and a thriving graduate program in neuroscience that provided a foundation for the establishment of the Western Institute of Neuroscience in 2022. The successful candidate will have access to research facilities and state-of-the-art instrument cores at Western that have been supported through major recent investments. These facilities and cores include but not limited to, a Biomedical Research Facility for animal housing (opens in 2023), a Neurobehavioral Core, a Western Advanced Microscopy Core, a Centre for Functional and Metabolic Mapping that includes 3T up to ultra-high field MRI imaging, and a new containment level 3 facility for imaging pathogens for knowledge translation.

St. Joseph’s Health Care hosts a multidisciplinary pain clinic seeing over 1000 new patients each year while a robust functional neurological program is situated at the University hospital. Dedicated clinical services for pain management include a multidisciplinary pain clinic and a functional neurosurgery program which both offer opportunities for patient recruitment to clinical studies.

With roots going back a century and a half, London Health Sciences Centre (LHSC) is one of Canada’s largest research-intensive acute tertiary and quaternary care teaching hospitals. Attracting top clinicians and researchers from around the globe, we excel in specialized care programs and services. As leaders in innovation and health system transformation, we advance health care for patients in Ontario, our nation, and the world.

Contact information

To apply:

Applications will be accepted until the position is filled. Review of applications will begin after August 1, 2023, with an anticipated start date of January 1, 2024, or as negotiated.

Interested candidates should send a letter of intent that includes

a) an overview of past research and description of proposed research plan,

b) plan to build collaborations, networks, and knowledge translation locally and beyond,

c) history and commitment to mentorship,

d) statement on commitment to diversity, equity and inclusion, along with a curriculum vitae, and the names and contact information of three referees and also complete, sign and include the form at the following link:



Dale W. Laird, PhD, Assistant Dean, Research Chairs and Awards

Schulich School of Medicine & Dentistry, Clinical Skills Building, Western University

London, Ontario CANADA N6A 5C1



Business Addresses:

Western University, 1151 Richmond Street, N., London, Ontario N6A 5B8,;

London Health Sciences Centre, 800 Commissioners Road E., London Ontario, N6A 5W9,;

St. Joseph’s Health Care London, 268 Grosvenor Street, London Ontario, N6A 4V2,


Positions are subject to budget approval. Applicants should have fluent written and oral communication skills in English. The University invites applications from all qualified individuals. Western is committed to employment equity and diversity in the workplace and welcomes applications from women, members of racialized groups, Indigenous peoples, persons with disabilities, persons of any sexual orientation, and persons of any gender identity or gender expression.

In accordance with Canadian Immigration requirements, priority will be given to Canadian citizens and permanent residents.

Accommodations are available for applicants with disabilities throughout the recruitment process. If you require accommodation for interviews or other meetings, please contact the Selection Committee at 519-661-2111 ext. 88141.

Posting end date: 2023/07/31

With autism, the brain adapts to blood vessel problems by changing how it uses energy

Baptiste Lacoste OHRIDr. Baptiste Lacoste wants to find out what’s going wrong with the blood vessels in the autistic brain. His team was the first to discover that these blood vessels don’t work properly in mouse models of autism, and there’s some cellular evidence that this happens in humans as well. Now, in a new study published in Cell Reports, the team has found that blood vessel problems in this mouse model cause the brain to absorb glucose at a much higher rate than a neurotypical brain, consistent with less efficient metabolism. Continue reading

Assistant Professor (Neurobiology) – University of British Columbia, Okanagan Campus

The Irving K. Barber Faculty of Science at the University of British Columbia, Okanagan Campus, invites applications for the position of Assistant Professor (Neurobiology).

The Department of Biology, in the Irving K. Barber Faculty of Science at the University of British Columbia (UBC) Okanagan campus invites applications for an appointment at the rank of Assistant Professor, with specialization in cellular/molecular neurobiology.  This is a tenure-track position and is expected to start on July 1, 2024, or soon thereafter.

We encourage applications from candidates performing fundamental studies of development, neurogenesis, neural circuit biology, plasticity, glia-neuron interactions, and/or molecular and cellular mechanisms of neurodegeneration, neuroimmunology, mood disorders, pain, or the gut-brain axis.  The department will consider a wide range of subfields and study models in molecular and/or cellular neurobiology. Relevant areas of current departmental research include neurotrophin action, neuroimmune mechanisms, neurodegeneration, and neuronal stress using murine and Drosophila models.

The candidate must hold a PhD in biology or a related field, with relevant postdoctoral research expertise in neurobiology and demonstrated potential for excellence in research. Candidates are expected to demonstrate an exceptional commitment to the teaching and mentoring of students. Evidence of strong commitment to equity, diversity, and inclusion is also required. Knowledge of best practices in open science is an asset.

As one of the campuses of the University of British Columbia, UBC Okanagan offers a globally recognized degree at a more intimate campus with 9,600 undergraduates and 1,065 graduate students. Biology is one of four administrative units within the Irving K. Barber Faculty of Science. The Biology Department’s 28 faculty are actively engaged in mentoring >900 undergraduate students in five majors (Biology; Biochemistry and Molecular Biology; Microbiology; Ecology, Evolutionary and Conservation Biology; Zoology), as well as >80 MSc and PhD students. In the past five years, the department has received a total of $15 million in research funding to support >400 different projects.

UBC Okanagan is located in the city of Kelowna, on the traditional and unceded territory of the Syilx people of the Okanagan nation.  Kelowna is connected by direct flights to major Canadian and USA cities and the region is considered one of the most desirable regions to live in Canada. For more information about the Okanagan Campus, see For more information about the Faculty of Science, see  Information about the surrounding community can be found at:


How to Apply

Applications are to be submitted online and must include:

  • a cover letter that includes a statement as to whether the candidate is legally entitled to work in Canada
  • a curriculum vitae
  • a two-page statement of research plans, which must: articulate a long-term vision that demonstrates impact in the field and/or on society; outline short-term objectives; and define the methodologies to be employed
  • a one-page statement of teaching experience and teaching philosophy
  • a one-page diversity statement (i.e., experience working within a diverse environment and your contributions to creating/advancing a culture of equity and inclusion on campus)
  • the names of three referees who have agreed to submit letters of reference, if requested


The deadline for application is September 15, 2023.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority

The Irving K. Barber Faculty of Science at UBC Okanagan is deeply committed to increasing the diversity of our community. We ask that all applicants complete a voluntary survey at

( that that will help us to assess the effectiveness of our efforts to reach a broad group of potential applicants.

UBC is committed to creating and maintaining an inclusive, non-discriminatory and accessible work environment for all members of its workforce. UBC is also committed to ensuring that the application and interview process is accessible to all applicants.  If you require accommodations or have questions about UBC benefits, services or accommodations policies, please contact Jacky Ivans, Relocation and Benefits Associate at .

Please direct inquiries to: Ms. Cheryl Craig, Department of Biology e-mail:

Posting End Date

September 16, 2023

Tenure-Track Assistant/Associate Professor of Comparative Medicine

The Department of Biomedical Sciences at the Atlantic Veterinary College and the UPEI Faculty of Medicine invite applications for a full-time tenure-track position in Comparative Medicine. Appointment will be at the Assistant or Associate Professor Level.

The successful candidate will hold a cross-appointment between the Faculties of Medicine and Veterinary Medicine. Primary undergraduate teaching responsibilities will be in the Faculty of Medicine in one of several pre-clinical disciplines based on the candidate’s area of expertise. The candidate will be expected to develop a strong externally funded independent research program, teach graduate courses, and mentor graduate and undergraduate research students in Biomedical Sciences. Members of the Department of Biomedical Sciences conduct basic and applied research particularly in the areas of physiology, microanatomy, pharmacology and toxicology, cell and molecular biology and neuroscience. Biomedical Sciences offers accredited MSc and PhD degree programs and hosts world class laboratory and animal facilities with access to clinical veterinary specialty services.

The new UPEI Faculty of Medicine will house a joint MD degree in partnership with Memorial University of Newfoundland with an expected start date of September 2025.

The successful applicant will have a PhD with relevant post-doctoral experience and a significant record of publications in a discipline relevant to departmental strengths. Salary is commensurate with credentials and experience and is subject to budgetary approval.

For additional details and application instructions see the attached PDF and/or the UPEI website (

Contact information
Dr. Sue Dawson, Professor and Chair
Department of Biomedical Sciences
University of Prince Edward Island
550 University Avenue
Charlottetown, PE C1A4P3
Phone: 902-566-0808

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Assistant Professor, Teaching Stream-Contractually Limited Term Appointment-Behavioural Neuroscience – University of Toronto

Date Posted: 06/22/2023

Closing Date: 07/27/2023, 11:59PM ET

Req ID: 31460

Job Category: Faculty – Teaching Stream, Contractually Limited Term Appointment

Faculty/Division: Faculty of Arts & Science

Department: Dept of Psychology

Campus: St. George (Downtown Toronto)


The Department of Psychology in the Faculty of Arts and Science at the University of Toronto invites applications for a two-year contractually limited-term appointment (CLTA) in the area of Behavioural Neuroscience. The appointment is at the rank of Assistant Professor, Teaching Stream, with an expected start date of September 1, 2023 and ending on August 31, 2025.

Applicants must have earned a Ph.D. degree in Psychology, Neuroscience, Cognitive Science or a related area by the time of appointment or shortly thereafter. Applicants must also possess a record of excellence in teaching and teaching-related scholarly activities. We seek candidates whose teaching interests complement and strengthen our existing departmental strengths. Candidates must have teaching expertise in a degree granting program at the undergraduate level including lecture preparation and delivery. Additionally, candidates must possess a commitment to excellent pedagogical practices and interest in teaching-related scholarly activities.

Evidence of excellence in teaching and pedagogical inquiry can be demonstrated through teaching experience and accomplishments, awards and accolades, presentations at significant conferences, the teaching dossier submitted as part of the application (with required materials outlined below) as well as strong letters of reference from referees of high standing.

Candidates are also expected to show evidence of a commitment to equity, diversity, inclusion (EDI), and the promotion of a respectful and collegial learning and working environment demonstrated through the application materials.

The position involves teaching undergraduate courses primarily in behavioural neuroscience, with the ability to teach Cognitive Neuroscience, Learning and Plasticity, and Physiology and Psychology of Emotion as particular assets. The position may also include opportunities to teach in other relevant areas including statistics, research methods, learning, memory, psychopharmacology, sensation and perception, circadian rhythms and biological timing, emotion, and neurological disorders ( Additional responsibilities may include supervision of undergraduate research projects and departmental service.

Salary will be commensurate with qualifications and experience.

All qualified applicants are invited to apply by clicking on the link below. Applicants must submit a cover letter; a current curriculum vitae; and a complete teaching dossier to include a teaching statement, sample syllabi and course materials, and teaching evaluations. We seek candidates who value diversity and whose research, teaching and service bear out our commitment to equity and inclusion. Candidates are therefore also asked to submit a 1-2 page statement of contributions to EDI, which might cover topics such as (but not limited to): research or teaching that incorporates a focus on underrepresented communities, the development of inclusive pedagogies, or the mentoring of students from underrepresented groups.

Applicants must provide the name and contact information of three references. At least one reference must primarily address the candidate’s teaching. The University of Toronto’s recruiting tool will automatically solicit and collect letters of reference from each once an application is submitted (this happens overnight). Applicants, however, remain responsible for ensuring that references submit letters (on letterhead, dated, and signed) by the closing date. More details on the automatic reference letter collection, including timelines, are available in the FAQs.

Submission guidelines can be found at Your CV and cover letter should be uploaded into the dedicated fields. Please combine additional application materials into one or two files in PDF/MS Word format. If you have any questions about this position, please contact Professor Geoff MacDonald, Acting Chair of the Department of Psychology For more information about the Department of Psychology, please visit our website

All application materials, including reference letters, must be received by July 27, 2023.

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.


Diversity Statement

The University of Toronto embraces Diversity and is building a culture of belonging that increases our capacity to effectively address and serve the interests of our global community. We strongly encourage applications from Indigenous Peoples, Black and racialized persons, women, persons with disabilities, and people of diverse sexual and gender identities. We value applicants who have demonstrated a commitment to equity, diversity and inclusion and recognize that diverse perspectives, experiences, and expertise are essential to strengthening our academic mission.

As part of your application, you will be asked to complete a brief Diversity Survey. This survey is voluntary. Any information directly related to you is confidential and cannot be accessed by search committees or human resources staff. Results will be aggregated for institutional planning purposes. For more information, please see

Accessibility Statement

The University strives to be an equitable and inclusive community, and proactively seeks to increase diversity among its community members. Our values regarding equity and diversity are linked with our unwavering commitment to excellence in the pursuit of our academic mission.

The University is committed to the principles of the Accessibility for Ontarians with Disabilities Act (AODA). As such, we strive to make our recruitment, assessment and selection processes as accessible as possible and provide accommodations as required for applicants with disabilities.

If you require any accommodations at any point during the application and hiring process, please contact

Click here for electronic copy of the posting and link to apply:

Contact information:       Professor Geoff MacDonald, Acting Chair of the Department of Psychology

Posting end date:             2023/07/27