PhD position: Brainstem control of locomotion in mice

PROJECT: The locomotor role of dopaminergic cells is classically attributed to their ascending projections to the basal ganglia that project to brainstem locomotor circuits that controls locomotion. However, descending dopaminergic projections to brainstem locomotor circuits were uncovered (Ryczko et al. PNAS 2013, PNAS 2016, J Neurosci 2017, J Neurosci 2020). In lamprey, these descending projections increase locomotor activity. In mammals, their role remains to be determined.

The student will address this issue in mice using in vivo optogenetics and chemogenetics, movement analysis, patch-clamp electrophysiology or calcium imaging in brain slices, viral injections or neuroanatomy. The new knowledge will provide a better understanding of the relation between dopaminergic and locomotor neurons and help identify new clinical strategies to improve locomotor function in Parkinson’s disease.

REQUIREMENTS: The candidate should have completed a MSc in neuroscience or a close field. The ideal candidate would have experience in patch-clamp electrophysiology, optogenetics or calcium imaging in slices, in vivo optogenetics or chemogenetics, virus injections, matlab scripting, and a keen interest in motor control.

HOST LABORATORY: Pr. Ryczko has expertise in the neural control of locomotion and published his research in excellent journals (PNAS, Science, Science Robotics, Journal of Neuroscience…). The lab receives grant support by the CIHR, NSERC, FRQS, CFI and ERC. We are equipped for optogenetics, viral injections, patch-clamp recordings, confocal and two photon calcium imaging, high-resolution movement analysis based on deep learning, and microscopy (confocal, light-sheet, two-photon, STED).

START: The student could start either in May 2024 or September 2024.

APPLY: Candidates should send a letter of interest, a CV, a complete record of their academic results and three references at: dimitri.ryczko@gmail.com. Please specify where you found the job post.

Contact information : dimitri.ryczko@gmail.com

Urgent appeal to recapitalize the Canada Brain Research Fund

We invite you to read a letter calling for urgent recapitalization of the Canada Brain Research Fund we recently sent to

The Honourable Ya’ara Saks, Minister of Mental Health and Addictions of Canada
The Honourable Mark Holland, Minister of Health of Canada
The Honourable Chrystia Freeland, Minister of Finances of Canada
The Right Honourable Justin Trudeau, Prime Minister of Canada

Read the letter here: CAN-Brain-Canada-support-letter-2024

M.Sc. & Ph.D. Positions at McGill University in Computational Analysis of Behavior and Brain dynamics with Computer Vision/Machine Learning

Positions Overview:

The Mohajerani lab (https://douglas.research.mcgill.ca/majid-mohajerani/) at McGill University is seeking prospective M.Sc. or Ph.D. to join our lab for Winter 2025 semester. The focus of student’s project will be on analysis of animal behaviour and brain activity using deep learning tools. To be qualified for this position, ideal candidates must have a solid background in computer vision and be familiar with neuroscience. As part of this role, students also must complete coursework for neuroscience program at McGill (www.mcgill.ca/ipn/), a university known for its world-class research and academic excellence, providing them an intellectually stimulating and inspiring environment for their career growth. We are searching for dedicated researchers to join our lab, so if you like tackling challenges, you are welcome to apply! Lastly, the successful candidate must have a collaborative spirit, as this role involves cooperation with multiple institutions and investigators.

Deadline: March 31st, 2024

Key qualifications:

  • Academic Background: M.Sc. or B.Sc. in computer science, computer engineering, neuroscience, or related fields. Solid foundation in machine learning , and knowledge of experimental neuroscience (e.g., optical imaging/ontogenetic, electrophysiology, behavioural assessment) will be a bonus.
  • Technical Knowledge: Familiarity with deep learning libraries (TensorFlow, PyTorch), and image processing in Python.
  • Soft Skills: Individuals who are driven by curiosity, practical problem-solvers, and team players.
  • Passionate About Neuroscience: A genuine interest in computational, and/or behavioural neuroscience and a commitment to contributing to the field.

What we offer:

  • A Focus on Behavioural Neuroscience: Dive deep into research that aims to unravel the complexities of behaviour and brain dynamics through AI. Our projects span various aspects of the field, offering a rich environment for academic and personal growth.
  • Collaborative Environment: Work alongside leading scientists in a supportive, interdisciplinary team where your ideas and contributions are valued.
  • Resources: Access to cutting-edge technology and resources to facilitate your research, experimentation, and learning.
  • Real-World Impact: Engage in projects that aim to translate scientific discoveries into practical applications, making a tangible difference in the field and beyond.
  • Academic Excellence: As part of McGill University, you’ll be immersed in an environment known for its high standards of research and education.

How to Apply:

If you’re passionate about machine learning and want to work in a dynamic and exciting environment, please apply with your resume and a cover letter describing your relevant experience and why you’re the right fit for this role. We strive to ensure that our team is diverse, equitable, and inclusive. All qualified applicants, including women and members of visible minority groups, are welcome to apply. If you meet all the requirements, please fill out the following form:

https://docs.google.com/forms/d/1TK_TfBSzkqNcR_DYt82HGb0MImX_1mthtegbxbkJtbI/edit

Post-doctoral position in comparative study of reward learning, stress and psychedelics- McGill University

Do you want to know what mice think about on mushrooms? Are you interested in making inferences in mice and humans?

The Behavioural Neurogenomics Lab (https://www.bagotlab.org) at McGill University is looking for a highly motivated computational neuroscience postdoc to lead a newly funded collaboration examining the neural bases of effects of stress and psychedelics on reward processing in mice and humans. This is a fully funded position intersecting computational modeling, neural circuit interrogation and robust behavioural paradigms. Based in Montreal, the candidate will work closely with the Noise Lab at Université de Montreal (https://ebitzlab.com/) and the Mayo Lab (https://profiles.ucalgary.ca/leah-mayo) at University of Calgary to develop new approaches for the comparative study of the neural processing of reward.

The candidate must have a PhD in computational neuroscience, psychology, cognitive science or a quantitative discipline as well as fluency in Matlab or Python and experience in statistical data analysis and an interest in translational or comparative research. Ideally, the candidate would have some background in cognitive and/or reinforcement learning models, generalized linear models, hidden Markov models or probabilistic graphical models.

Anticipated start date April 1, 2024 for an initial term of 1 year with the possibility of renewal.

Come join an exciting, diverse team in a unique city with a supportive, and highly collaborative environment.

To apply, please send a PDF of your CV to rosemary.bagot@mcgill.ca with a list of three potential references to contact. In your email, please describe 1) why you are interested in the position and 2) how your prior experience relates to this research opportunity.

Posting end date: 2024-03-30

Assistant Professor, Department of Anatomy, Physiology, and Pharmacology – University of Saskatchewan

Applications are invited from qualified individuals for up to two (2) full time, tenure-track Assistant Professor positions in the Department of Anatomy, Physiology, and Pharmacology (APP) at the University of Saskatchewan, to begin July 1, 2024.

The successful candidate(s) will have a PhD degree in any area of anatomy, physiology, pharmacology, or cell or developmental biology and should have post-doctoral experience in a related research field. Key selection criteria will include research excellence, originality, and potential for research impact. The successful candidate(s) will be expected to develop a strong externally-funded research program and be able to complement the research strengths of other APP faculty members. Particular areas of research strength include skeletal biology, cardiovascular physiology and pharmacology, respiratory pathophysiology, synchrotron imaging, and neuroscience. Expertise in one of these areas will be considered an asset, but candidates from other research areas will be considered. The selected candidate(s) will also contribute to teaching of undergraduate and medical students, and to the teaching and mentoring of graduate students.

The University of Saskatchewan’s main campus is situated on Treaty 6 Territory and the Homeland of the Métis. The University of Saskatchewan is located in Saskatoon, SK, a city with a diverse and thriving economic base, a vibrant arts community and a full range of leisure opportunities. The University has a reputation for excellence in teaching, research, and scholarly activities and offers a full range of undergraduate, graduate, and professional programs to a student population of over 26,000.

The salary band for an Assistant Professor position is from $99,945 to $120,099. This position includes a comprehensive benefits package which includes a dental, health and extended vision care plan; pension plan, life insurance (compulsory and voluntary), academic long term disability, sick leave, travel insurance, death benefits, an employee assistance program, a professional expense allowance, and a flexible health and wellness spending program.

Interested candidates must submit, via email (refer to req11804 in subject line): a cover letter, detailed curriculum vitae, a brief statement of research interests and plans (3 pages or less), a teaching statement (1 page), a statement on equity, diversity and inclusion (EDI) that includes a reflection on the candidate’s experiences with EDI and how those experiences will enrich this aspect of the department (1/2-1 page), and contact information for three references. Incomplete applications will not be considered.

Dr. TE Fisher
Professor and Head, Department of Anatomy, Physiology and Pharmacology
107 Wiggins Road, Rm GA20
Saskatoon, SK Canada S7N 5E5
Telephone: (306) 966-6530

Email: appadmin@usask.ca

Due to federal immigration requirements, we also ask candidates to indicate whether they are Canadian citizens, permanent residents, or are otherwise already authorized to work at this position for the duration of the appointment, with an explanation if this last category is indicated.

Review of applications will begin January 3, 2024 but applications will be accepted and evaluated until the positions are filled. The anticipated start date is July 1, 2024.

The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. The university must, however, comply with federal immigration requirements. All qualified candidates are encouraged to apply, but Canadian citizens and permanent residents will be given priority.

Contact information

appadmin@usask.ca

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Postdoctoral Position Available in the Breton-Provencher lab at U. Laval: Noradrenaline, acetylcholine and learning

Join our dynamic and innovative research team at the CERVO Brain Research Centre of Université Laval in Québec City, Canada. Established in 2021, our team is dedicated to unraveling the intricate mechanisms underlying learning and memory. We are excited to announce a funded postdoctoral position focused on exploring the role of neuromodulation in learning consolidation.

Project Overview:
The successful candidate will engage in a stimulating project investigating the impact of neuromodulators, such as acetylcholine and noradrenaline, on learning consolidation. Utilizing advanced methods like in vivo electrophysiology, two-photon imaging, and animal behavior analysis, the project aims to elucidate the neural mechanisms governing the consolidation of motor learning. This project aligns with our general research focus, which centers on understanding the influence of neuromodulatory systems on learning. For further insights into our work, please refer to Breton-Provencher and Sur’s publication in Nature Neuroscience (2019) and Breton-Provencher et al.’s recent article in Nature (2022).

Requirements:

  • Ph.D. in Neuroscience or a related field.
  • Proficiency in one or more of the following: in vivo electrophysiology, two-photon imaging, animal surgery, programming languages (Python/MATLAB), and data analysis.
  • Expertise and productivity in neuroscience research.
  • Independence in research, creative problem-solving skills, and a collaborative mindset.
  • Strong communication skills and the ability to work effectively within a team.

Lab Environment:
Our lab fosters a collaborative, supportive, and intellectually stimulating environment where creativity, scientific rigor, and innovative thinking are valued. As a young lab, we provide ample opportunities for professional growth and encourage independence in research pursuits. We offer support for various career paths, whether in academia or industry. The lab is located in Québec City, known for its safety, affordability, and family-friendly environment.

Funding:
The project is funded by a 3-year grant from the US Department of Defense. Additionally, candidates can apply for several other funding opportunities for international post-docs available through the Québec (e.g., FRQS) and Canadian (e.g., CIHR, NSERC) funding systems. The lab is supported by NSERC, Brain Canada, CFI, FNFR, and the CERVO Research Centre.

Interested candidates of ALL BACKGROUNDS should submit a cover letter describing research interests and relevant experience, along with a curriculum vitae.

Join us in unraveling the mysteries of neuromodulator systems in the brain!

Visit the vbplab.com for more info!

2023 CAN Parliament Hill Day

CAN held its second in-person Parliament Hill Day in Otttawa on November 7, 2023. This presented an exceptional opportunity for a team of CAN advocates to meet face-to-face or virtually with members of Parliament, Senators, Parliamentary staff members and important senior civil servants to advocate for a increased support for the major federal funding agencies in Canada (Canadian Institutes of Health Research (CIHR), Natural Sciences and Engineering Research Council of Canada (NSERC), Social Sciences and Humanities Research Council (SSHRC) and graduate student and postdoctoral fellowships and for making research on Brain and Mental Health a national priority. Continue reading

Watt Lab at McGill University seeking postdoctoral research fellow

We are currently seeking an outstanding candidate to study cerebellar circuits in health and in disease, in particular in models of motor coordination diseases like ataxia. The applicant should be experienced in either in vivo recording techniques and/or in vivo imaging techniques. Candidates should have doctoral experience in neuroscience, biology, or a related field. Preference will be given to candidates with expertise in in-vivo electrophysiology and/or 2-photon imaging, and the ideal candidate will have authored high-profile publications using these techniques. Duties will include performing experiments, analyzing and presenting data at local, national and international conferences, writing manuscripts as well as occasionally providing training to other lab members. Collaborative work with other members of the neuroscience community is also welcome.
The Watt lab is located at McGill University in beautiful Montreal, Canada. Montreal is a vibrant, multicultural city that provides an excellent quality of life. McGill and its neighbouring universities provide an exceptionally rich neuroscience community.

The initial appointment would be for 2 years, with the possibility of extension. This position is fully funded with a competitive salary. In addition, applicants would be encouraged to apply for independent funding, which is available for both Canadian and international applicants.

Full applications, including a cover letter, a full CV, a brief outline of current research, and the names and contact details of three academic referees should be sent to Dr. Alanna Watt at alanna.watt@mcgill.ca. In the subject line, please enter Postdoc Research Fellow and your name.

Closing date: 15 January 2024 Start date is flexible.

Both the Watt lab and McGill University are committed to diversity and equity in employment. We welcome applications from: women, Indigenous persons, persons with disabilities, ethnic minorities, persons of minority sexual orientation or gender identity, visible minorities, and others who may contribute to diversification. All qualified applicants are encouraged to apply; however, in accordance with Canadian immigration requirements, Canadian citizens and permanent residents will be given priority.

Contact information

alanna.watt@mcgill.ca

Posting end date

2024/01/15

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Neuroscience and Mental health – Assistant Professor – CERVO Brain Research Centre, Université Laval

The CERVO Brain Research Centre (cervo.ulaval.ca), affiliated with Université Laval, is seeking applications for an Assistant Professor position that could begin as early as July 2024. This recruitment is made possible by the remarkable growth of the Research Centre in recent years and several major initiatives funded by the Canadian and Quebec governments. The selected candidate will be presented to join Université Laval through its internal competitions.

CERVO hosts more than 80 principal investigators and a total of 550 graduate students, post-docs, and staff scientists. The Centre is devoted exclusively to the study of neurosciences, mental health, and addiction. Its mission is to advance knowledge about the causes and treatments of neurological and psychiatric illnesses by developing new technologies and methodologies to unravel the mysteries of the brain and by continuously linking basic and clinical research. This is pursued by multidisciplinary approaches and the centre’s strong expertise in Cellular and Molecular Neurosciences, Systems Neurosciences, Clinical and Cognitive Neurosciences, Psychiatry, Neurophotonics, Optics/Photonics, Mathematics, and Artificial Intelligence. Emphasis is put on collaborative research across these disciplines.

Applicants must have a PhD or MD/PhD and a post-doctoral training, with an excellent record of research productivity. The successful candidates will have demonstrated ability or outstanding potential to develop an internationally recognized research program in the Neurosciences and Mental Health, together with the capacity of securing competitive research grants. Teaching interests will be an asset. The recruited candidates will be expected to supervise graduate students.

Université Laval, located in Québec City, is one of Canada’s leading universities and the oldest French-speaking institution in North America; applicants will be expected to develop language skills in French, mainly for teaching purposes. By choosing the CERVO Brain Research Centre and Université Laval, you could benefit from several measures to facilitate the relocation and integration of you and your family, such as orientation for new professors and peer mentoring, free French lessons, support for settling in Quebec City (including networking and advice on housing and school/daycare needs), and job search assistance for your spouse/partner. Non-Canadian candidates also receive full support and legal advice for immigration procedures.

The CERVO Brain Research Centre supports the principle that excellence and equity are compatible and complementary. We have an active Equity-Diversity-Inclusion committee. We welcome and encourage applications from racialized and visible minority individuals, women, First Peoples in Canada (Indigenous) persons, persons with disabilities, ethnic minorities, 2SLGBTQI+ individuals, as well as all qualified individuals with the skills and knowledge to engage productively with diverse research topics and communities.

Applications in a single pdf file should include: A cover letter outlining specific interests in the position, a scientific CV, a 3-page research program outlining the short and long-term goals. Applications must be sent electronically to recruitment@CERVO.ulaval.ca. Three letters of reference should also be sent directly by mentors of the candidate at the same email address. Screening of applications will begin by December 4, 2023. Selected applicants will be contacted for a pre-interview online, starting in January 2024.