Graduate student position: Influence of dopaminergic signals on motor plasticity and recovery – EthierLab – Université Laval

The laboratory of Dr. Christian Ethier is currently recruiting graduate students at the masters or PhD levels for a research project in the field of motor neuroscience to begin during the fall 2020 or winter 2021 semesters.

The goal of this project is to investigate the potential of dopaminergic signals to drive neuronal plasticity and promote motor recovery in rat models of stroke. The project will involve behavioural training, surgical injections and implants, optogenetics and immunohistochemistry, and will take place in the dynamic CERVO Brain Research Center.

Applicants from diverse scientific background will be considered, including engineering, biology and neurosciences. Priority will be given to students with knowledge or skills in:

  • Systems neuroscience
  • Motor system (cortex, basal ganglia, spinal cord function and anatomy)
  • Programming (Matlab, Python, C/C++)
  • Neural plasticity
  • Rodent behavioral tests
  • Dopaminergic systems and function
  • Chronic implants, rodent surgical skills
  • Electrical, optogenetic stimulation
  • Immunohistochemistry, RNAscope, Fluorescence imaging

Contact information

To apply or obtain further information, please send your CV, a motivation letter, and the name of 3 references to Christian Ethier directly: christian.ethier@fmed.ulaval.ca.

Posting end date

2020/09/25

Doctoral and Postdoctoral Researcher Position – Brouillette lab, Montreal

The Brouillette Lab at the Hôpital du Sacré-Coeur de Montréal (CIUSSS-NIM) invites applicants for a doctoral and postdoctoral researcher position in the field of Alzheimer’s disease and age-related memory deficits. Specific research topics include the effect of Aβ oligomers on sleep during aging, the impact of Aβ oligomers on different cell types in the hippocampus, the role of the phosphatase STEP on social memory, and blood biomarkers for early AD. We are using state-of-the-art equipment to perform laser microdissection, optogenetic, molecular/cellular biology, and behavioural testing with various animal models. These full-time positions and projects are supported by the Canadian Institutes of Health Research (CIHR) and the Weston Brain Institute. Funding is available for three to five years. The start date is immediate but flexible. Applications will be considered until the positions are filled. The annual stipend is consistent with CIHR funding levels.

Requirements

Candidates should have a degree in neuroscience, biochemistry, molecular/cellular biology, pharmacology, genetic, or a related field. Ideal applicants will have experience in molecular/cellular biology, animal behavioural testing, and knowledge of statistics. Additional preferred qualifications include experience with laser microdissection and optogenetic.

Contact information

Interested applicants should send their CV, a brief cover letter describing research experience and interests, university transcript, and contact information for 2-3 references by e-mail to Jonathan Brouillette (e-mail: jonathan.brouillette@umontreal.ca)

Principal Investigator
Dr. Jonathan Brouillette, Ph.D.
Assistant Professor
Department of Pharmacology and Physiology
Université de Montréal

Lab website:
https://pharmacologie-physiologie.umontreal.ca/recherche/chercheurs/jonathan-brouillette/
https://rechercheciusssnim.ca/profil/jonathan-brouillette/
https://recherche.umontreal.ca/nos-chercheurs/repertoire-des-professeurs/chercheur/is/in17687/

CAN Trainee research feature: Nuria Daviu, Hotchkiss Brain Institute

CAN Trainee research features are a new opportunity for Canadian neuroscience trainees to showcase their research through short video features. We aim to make this a weekly feature and to share on our website and social media accounts, so please consider submitting a proposal to us!

This week’s feature is Nuria Daviu, a researcher in the laboratory of Dr. Jaideep Bains, at the Hotchkiss Brain Institute.

Read the paper here: https://www.nature.com/articles/s41593-020-0591-0

Videos are also available here, with submission instructions

https://can-acn.org/can-trainee-research-features/

Check it out!

CAN Trainee Research Feature: Tasnia Rahman, McGill University

We are excited to launch a new opportunity for Canadian neuroscience trainees to showcase their research through short video features.  We aim to make this a weekly feature and to share on our website and social media accounts, so please consider submitting a proposal to us.  We would love to feature your research!

This week’s feature is: Tasnia Rahman, McGill University – Stentian structural plasticity in the developing visual system


Tasnia Rahman is a researcher in the laboratory of Dr. Edward Ruthazer at McGill University.

Read the paper here: https://www.pnas.org/content/117/20/10636

Videos will be also available here, with submission instructions

https://can-acn.org/can-trainee-research-features/

Congratulations to the Royal Society of Canada Class of 2020

Royal Society of Canada class of 2020

Congratulations to the Canadian neuroscientists newly elected fellows of the Royal Society of Canada, and to the incoming class of the college of new scientists.

“The Royal Society of Canada is delighted to recognise this year’s exceptional cohort of inductees, as the contributions of these outstanding artists, scholars and scientists have significantly impacted their respective disciplines at both national and international levels.” says RSC President Jeremy McNeil.
Congratulations to the following Canadian neuroscientists elected to this prestigious Society!

Continue reading

Vascular development may be at risk in autism

Early deficits in the formation of brain blood vessels translate into later autistic traits in miceBaptiste LAcoste OHRI

A Canadian collaboration led by Dr. Baptiste Lacoste has undertaken the first ever in-depth study of vasculature in the autistic brain. The product of four years of work, a paper published in the September issue of Nature Neuroscience lays out several lines of novel evidence that strongly implicate defects in endothelial cells—the lining of blood vessels—in autism.

Dr. Lacoste, a scientist at The Ottawa Hospital and an assistant professor in the University of Ottawa’s Faculty of Medicine and Brain and Mind Research institute, heads a lab that specializes in neurovascular interactions in health and disease. In collaboration with researchers at McGill University, Laval University, and the National Research Council of Canada, Dr. Lacoste’s team used a mouse model with one of the most common genetic mutations found in autism spectrum disorder—16p11.2 deletion, or “16p” for short. Continue reading

Unlocking the mysteries of the brain

Roberto Araya
Roberto Araya

A research team at CHU Sainte-Justine highlights the mechanisms underlying memory and learning capacity – specifically, how our brains process, store and integrate information.

How does our brain store information?

Seeking an answer, researchers at CHU Sainte-Justine and Université de Montréal have made a major discovery in understanding the mechanisms underlying learning and memory formation.

The results of their study are presented in Nature Communications.

Led by Professor Roberto Araya, the team studied the function and morphological transformation of dendritic spines, tiny protrusions located on the branches of neurons, during synaptic plasticity, thought to be the underlying mechanism for learning and memory. Continue reading

Graduate student position studying astrocyte-neuron interactions – Stobart laboratory, University of Manitoba

We are seeking a motivated graduate student with an interest in glial biology to work on an exciting project related to astrocyte ionotropic signaling and synaptic modulation. We have developed cutting-edge in vivo calcium imaging techniques to simultaneously monitor astrocyte and neuron activity and we will combine this with novel mouse models to probe astrocyte signaling in the tripartite synapse. There will be opportunities to learn animal handling, stereotaxic injection of AAVs, in vivo two-photon calcium microscopy, intrinsic optical imaging, histological techniques, behaviour testing, image analysis (with MATLAB), and statistics (with R). Please see our lab website for more information (www.stobartlab.com).
This work is funded by NSERC.

Eligibility:

  • Excellent academic standing
  • Strong written and oral communication skills
  • Good problem solving skills and the ability to think independently
  • Related lab experience is preferred (but not mandatory)

Successful candidates will be admitted to the graduate program through the College of Pharmacy, where they are expected to complete some course work in addition to research experiments. All students will be paid a stipend to cover tuition and living expenses.

Please submit a letter with statement of research interests, CV including research experience, a copy of recent transcripts and contact details for 2 references by email.

Contact information

Dr. Jill Stobart
Assistant Professor
College of Pharmacy
University of Manitoba
Apotex Centre
750 McDermot Ave.
Winnipeg, Manitoba
Canada

jillian.stobart@umanitoba.ca

Postdoctoral position in Montreal on immune mechanisms in Parkinson’s disease – Trudeau laboratory

Dr. Louis-Eric Trudeau’s laboratory at the Université de Montréal (University of Montreal) (www.labotrudeau.org) is looking for a post-doctoral fellow to join a team of scientists working on the connectivity and vulnerability of dopamine neurons. The ideal candidate will have previous training in cellular and molecular neuroscience, including physiological approaches, in neuroimmunology and interest in the immune mechanisms implicated in Parkinson’s disease. Preference will be given to candidates that have a track record including publications as first author and that are already in Canada or who can easily travel to Canada.

Interested individuals should email the lab principal investigator at: louis-eric.trudeau@umontreal.ca
Posting end date:  2020/12/31

Post-doctoral fellow position on the behavioural neuroscience of reward- Samaha laboratory – Universite de Montreal

Dr Anne-Noel Samaha’s laboratory at the Université de Montréal is looking for a post-doctoral fellow. I will hire someone whose primary expertise is in the behavioural neuroscience of reward.

Training in complementary techniques such as in vivo optogenetics, DREADDs, and in molecular biology assays is also important. The research work involves characterizing the neurobehavioural effects of different intravenous cocaine self-administration procedures in the rat.

If you have this expertise and are interested, please email anna.samaha@umontreal.ca

See also
https://pubmed.ncbi.nlm.nih.gov/?term=samaha+AN+montreal&sort=date

Candidates in Canada or who can easily travel to Canada will be given preference.

Contact information:

anna.samaha@umontreal.ca