Michael Poulter, a Professor/Principal Investigator with the Department of Physiology and Pharmacology and Robarts Research Institute – Department of Molecular Medicine, died on August 10, 2019 at the age of 60. Continue reading
A new study by Montreal scientists published today in Nature demonstrates that a gut infection can lead to a pathology resembling Parkinson’s disease (PD) in a mouse model lacking a gene linked to the human disease. Continue reading
The world’s largest brain research prize is Danish and is awarded by the Lundbeck Foundation. Each year, the Lundbeck Foundation awards 10 million DKK (approx. 1,3 million €) to one or more brain researchers who have had a ground-breaking impact on brain research. The prize and associated activities are at the very forefront of the Lundbeck Foundation’s ambitions to make Denmark the world’s leading brain research nation. The Brain Prize is an international prize and can be awarded to researchers from all over the world. Continue reading
Our nerves consist of small cables responsible for circulating information to every part of our body, allowing us, for instance, to move. These cables are actually cells called neurons with long extensions named axons. Continue reading
Cerebral cavernous malformations (CCM) is a rare disease that causes anomalies in tiny capillaries that transport blood throughout the brain. The disease manifests as irregularities that resemble raspberries, most often in the brain, that can lead to hemorrhage, stroke and seizures in afflicted individuals. The disease involves defects in one of three CCM genes (CCM1, CCM2, or CCM3) and affects nearly one in six thousand people. Currently, there is no clinically approved therapy to treat this disease; patients rely on invasive brain surgery for treatment, but some extreme forms cannot be treated surgically. Continue reading
Québec siblings with rare orphan disease lead to discovery of rare genetic diseases
Mutations in a gene involved in brain development have led to the discovery of two new neurodevelopmental diseases by an international team led by researchers at McGill University and CHU Sainte-Justine Research Center.
The first clues about the rare disorder arose after doctors were unable to diagnose why two siblings from Québec City were experiencing seizures and neurodevelopmental deficits. Desperate, the children’s family turned to Carl Ernst at the Douglas Mental Health University Institute in Montreal for answers. Continue reading
Congratulations to Geoffrey Hinton (University of Toronto), Joshua Bengio (Université de Montréal) and Yann LeCun (Boston University) who have won the 2019 Turing award for their work to understand neural networks using artificial intelligence and deep learning. The Turing Award is an annual prize given by the Association for Computing Machinery (ACM) to an individual selected for contributions “of lasting and major technical importance to the computer field”. The award is accompanied by a $1 million USD prize, to be shared by the three winners.
Read more on the Association for Computing Machinery website
Fathers of the Deep Learning Revolution Receive ACM A.M. Turing Award
Bengio, Hinton and LeCun Ushered in Major Breakthroughs in Artificial Intelligence
Geoffrey Hinton will be present at the CAN meeting on May 21, 2019, where he will present the CAN annual public lecture, which will be hosted by Blake Richards, from the University of Toronto. More here.
New therapeutic molecules developed at Toronto’s Centre for Addiction and Mental Health (CAMH) show promise in reversing the memory loss linked to depression and aging.
These molecules not only rapidly improve symptoms, but remarkably, also appear to renew the underlying brain impairments causing memory loss in preclinical models. These findings were presented at the American Association for the Advancement of Science (AAAS) Annual Meeting in Washington DC.
“Currently there are no medications to treat cognitive symptoms such as memory loss that occur in depression, other mental illnesses and aging,” says Dr. Etienne Sibille, Deputy Director of the Campbell Family Mental Health Research Institute at CAMH and lead scientist on the study. Continue reading
The Brain Prize 2019: French neuroscientists honoured for outstanding research into small vessel strokes in the brain
Aiming for treatment they have spent more than 30 years describing, understanding and diagnosing the most common hereditary form of stroke, CADASIL. For this, the four French neuroscientists are now receiving the world’s most valuable prize for brain research – the Lundbeck Foundation Brain Prize, worth 1 million euros. Continue reading