Master’s Position Available to Study the Role of the Unfolded Protein Response (UPR) during Traumatic Brain Injury – Lindsey/Logue Labs, University of Manitoba

This project uniquely investigates the role of the unfolded protein response (UPR) in regulating the regenerative ability of neural stem cells following traumatic brain injury (TBI) using the zebrafish model. The objective of the proposed study is to identify the temporal dynamics of UPR signaling during the repair process, characterize the cell types in which the UPR is activated, and ask if modulating UPR signaling can impact upon repair after TBI. The successful candidate will be jointly supervised by Dr. Benjamin Lindsey (expert in neural stem cells and repair in the zebrafish model) and Dr. Susan Logue (Canada Research Chair in Cell Stress and Inflammation) and learn cutting edge cell biology, microscopy and molecular biology techniques. The successful candidate will be admitted to the Human Anatomy and Cell Science graduate program where they will be expected to complete coursework in addition to their lab based research.

Eligibility Requirements:

• Excellent academic standing
• Strong work ethic and passion for discovery
• Interest in neuroscience, cell signaling, and microscopy
• Experience or interest in using animal models
• Excellent written and oral communication skills

Deadline: June 1, 2021; Start Date: September 1, 2021
Contact information:

benjamin.lindsey@umanitoba.ca

Download a PDF version of this advertisement: Graduate-Student-Posting-UPR-TBI-Lindsey-Logue-Team.pdf

Posting end date 2021/08/31

Postdoctoral or Graduate Student Position: Corticothalamic synaptic physiology in a Rett Syndrome mouse model

Corticothalamic synaptic physiology in a Rett Syndrome mouse model

2 year funded Postdoctoral position, University of Victoria, BC Canada – available immediately

Rett syndrome is a neurodevelopmental disorder which manifests postnatally due to loss of function of an X-linked transcription factor MECP2, which controls various aspects of neuronal and synapse maturation. Studies will be performed primarily on female mice heterozygous for Mecp2 in which approximately half of neurons express the wild type and half the mutant allele. By utilizing a GFP-based nuclear marker we identify neurons expressing the wild-type or non-functional (mutated) Mecp2 allele for targeted physiological recordings. Optogenetic stimulation of virally-expressed channel rhodopsin will be used to investigate the relative strength of input from thalamus to cortex and feedback from cortex to thalamus for mutant versus wildtype neurons. Preference will be given to a researcher with experience in whole cell patch clamp recording (current and or voltage clamp) in acute brain slices or in vivo. Funded by the International Rett Syndrome Foundation. Contact Dr. Kerry Delaney, kdelaney@uvic.ca

More information about UVic Neuroscience can be found at https://www.uvic.ca/medsci/neuroscience/

The Delaney lab: https://web.uvic.ca/~neurolab

Publications:
https://pubmed.ncbi.nlm.nih.gov/?term=delaney+rett

Victoria as a place to live:
https://www.tourismvictoria.com

 

Contact information

kdelaney@uvic.ca
250 472 5657

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IBRO – MBL and CSHL Fellowships

The IBRO (International Brain Research Organization) US-Canada Regional Committee (USCRC) is pleased to announce our 2021 fellowships program that will cover the cost for PhD students and postdoctoral fellows training in neuroscience in Canada to attend advanced neuroscience courses or meetings at the Marine Biological Laboratories (MBL) at Woods Hole, MA., and Cold Spring Harbor Laboratory (CSHL), NY.

For MBL, all trainees are welcomed to apply but preference will be given to trainees belonging to minority groups (Indigenous communities in Canada, visible minorities, persons with disabilities, women, and other minorities) as
well as those in non-U15 Universities (http://u15.ca/). The MBL awards will cover the cost of tuition, room, and board. Fellowships are worth up to $11,000 per trainee depending on the course taken.

For CSHL, reduced registration fees for virtual meetings are available for trainees from non-U15 Universities (http://u15.ca/). If in-person courses resume in the second half of 2021, partial tuition support of up to $8,000 per trainee will be available.

The aim of this program is to increase diversity in neuroscience in Canada, by providing such trainees with access to cutting-edge research training in contemporary neuroscience.

Interested trainees should submit applications directly to the course of interest (see link below). Evaluation of applications and offers of admission to courses are made by the course leaders. Accepted candidates with the backgrounds mentioned above will be automatically considered for IBRO fellowship.

Eligible MBL courses: Neural Systems and Behavior, Neurobiology: Mechanisms & Advanced Approaches, Methods in Computational Neuroscience, Biology of the Inner Ear: Experimental and Analytical Approaches, Brains, Minds and Mechanisms, Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches, and Frontiers in Stem Cells and Regeneration.

Eligible CSHL courses: see link below.

MBL: http://www.mbl.edu/education/courses/
CSHL: https://meetings.cshl.edu/meetingshome.aspx

Please inform us when applying or if you have questions about eligibility.

Contact: sam.david@mcgill.ca

Graduate student position studying sensory learning and adult neurogenesis – Lindsey laboratory – University of Manitoba

We are seeking an outstanding graduate student with an interest in adult neurogenesis, and learning and memory to lead an exciting new project focusing on the role of adult neural stem cells for learning in response to changes in the sensory environment. To address this question our lab takes advantage of the zebrafish model that houses adult neurogenic zones in brain structures that process both sensory and cognitive input. We have established numerous transgenic lines to address this question and have recently setup a new Noldus DanioVision Behavioral System for experimental design and behavioral analysis. This position will provide trainees the opportunity to learn zebrafish animal husbandry, innovate new behavioral and sensory learning paradigms, perform advanced imaging including confocal microscopy, correlative electron microscopy, and 3-D brain imaging methods, as well as transgenic design. Please visit our laboratory website for more information (www.lindseylab.ca). This project is funded by NSERC.

Eligibility:

  • Excellent academic standing
  • Strong written and oral communication skills
  • Good problem solving skills and the ability to think independently
  • Ability to innovate new research methods
  • Related lab experience is preferred (but not mandatory)

The successful candidate will be admitted to the graduate program through the Department of Human Anatomy and Cell Science at the University of Manitoba, where they are expected to fulfill course work in addition to thesis based research. The candidate will be paid an annual stipend to cover tuition and living expenses.

 

Interested candidates are asked to submit a letter outlining their research interests, a CV including research experience and publications, a copy of recent transcripts and contact details for at least two references by email. Position start date is September 2021.

Contact information:

Dr. Benjamin Lindsey
Assistant Professor
Department of Human Anatomy and Cell Science
University of Manitoba
130 Basic Medical Science Building
745 Bannatyne Avenue
Winnipeg, Manitoba

Canada

 

Benjamin.lindsey@umanitoba.ca

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Posting end date: 2021/06/30

BrainsCAN Graduate Studentship Program at Western University

We are pleased to announce the “Call for Applications” for the BrainsCAN Graduate Studentship Program. This program is part of Western’s $66M BrainsCAN initiative, supported by the Canada First Research Excellence Fund (CFREF). The CFREF investment is intended to enable researchers at the University, along with their national and international academic and commercial partners, to seek answers to fundamental questions regarding how we learn, think, move and communicate.

Recruiting the next generation of neuroscience researchers is a key aim of BrainsCAN. The BrainsCAN Graduate Studentship Program has been developed to attract the world’s most promising prospective master’s and doctoral students in cognitive neuroscience to Western University.

Up to five BrainsCAN Graduate Studentships will be awarded in this competition to highly qualified individuals pursuing a collaborative research project in cognitive neuroscience. This Studentship is open to any prospective graduate student not currently, or recently, enrolled in a graduate program at Western, and will provide a minimum salary of $25,000 for 2 years for master’s students, and $35,000 for 3 years for doctoral students.

Already ranked amongst the best in the world in cognitive neuroscience and neuroimaging, Western researchers employ cognitive, computational, clinical, and translational approaches to understand and intervene in brain function. Our graduate students will have access to BrainsCAN-supported core facilities for neuroimaging; for studying human cognition, behaviour and sensorimotor control; for development and use of computational methods; and for establishing and exploring rodent and nonhuman primate models of cognition and behaviour. Skilled staff within these cores support state-of-the-art technical equipment including research-only MRI systems (3T, 7T, and 9.4T), laboratories for cognitive, behavioural, and electrophysiological testing in humans and animal models, advanced molecular techniques, a sleep laboratory, and access to a variety of neurological patient populations in affiliated teaching hospitals.

Applicants must identify and contact potential advisors at Western before applying. An interdisciplinary, collaborative approach, involving more than one lab is a requirement for application. Lastly, it is strongly recommended that all potential applicants review Western’s Graduate School Admission procedures and academic calendar prior to preparing their application.

The application deadline is January 4th, 2021.

Contact information For more information, please see: https://brainscan.uwo.ca/programs/graduate_studentship_program/index.html

Contact: brainscan@uwo.ca
Posting end date 2021/01/03

PhD scholarship in Biomedical Sciences – Université du Québec à Trois-Rivières

Description

Candidates are invited to submit their application for a PhD scholarship in Biomedical Sciences in the field of human olfactory plasticity at the University of Quebec in Trois-Rivières under the supervision of Prof Johannes Frasnelli. At the lab for Chemosensory Neuroanatomy, state-of-the-art techniques such as olfactory event-related potentials, MR imaging and behavioral methods are used to understand how chemosensory function and brain anatomy/function are linked. Our projects are supported by the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC) of Canada and the Fonds de Recherche du Québec – Santé (FRQS). The amount of the scholarship corresponds to CIHR guidelines and is available for three to five years. The position is available immediately. Start date is flexible.

Qualifications

The successful candidate will have an MSc degree in Biomedical Sciences, Psychology, Biomedical Engineering, or a related field. Ideal applicants will have some experience in biomedical imaging, human electrophysiology, chemosensory testing, and knowledge of statistics.

Contact information

Interested applicants should send their CV, a brief cover letter describing their research experience and interests, transcripts, and contact information for 2-3 references by email to Dr. Johannes Frasnelli (johannes.a.frasnelli@uqtr.ca)

Dendritic Algorithms for Perceptual Learning – Muller lab at University of Montreal / CHU Ste-Justine Research Center / Quebec Artificial Intelligence Institute

I’m happy to announce the Architectures of Biological Learning Lab is Hiring!

I’m looking for exceptional candidates at the MSc, PhD or post-doc level to work on “Dendritic Algorithms for Perceptual Learning”. The project will employ simulations of pyramidal neurons and plasticity, and deep convolutional networks to study representation learning in the neocortex. Prior experience with Python, NEURON, and/or PyTorch would be an asset.

This project will be undertaken in collaboration with Profs. Yoshua Bengio (UdeM, Mila), Roberto Araya (UdeM, CRCHUSJ), and Blake Richards (McGill, Mila).

Start date: As soon as possible. Applications will be accepted until the position is filled. Selection of applications will begin on October 15th, 2020.

Montreal, Canada is a thriving international hub for Artificial Intelligence and Neuroscience research, with a booming AI industry. It’s where Donald O. Hebb originally formulated Hebbian Learning. It’s also a vibrant, funky, cosmopolitan yet affordable city of over 4 million, referred to as “Canada’s Cultural Capital” by Monocle magazine. In 2017, Montreal was ranked the 12th-most liveable city in the world by the Economist Intelligence Unit in its annual Global Liveability Ranking, and the best city in the world to be a university student in the QS World University Rankings.

For more details and instructions how to apply, please visit: https://bit.ly/3l1PGFH

Contact information

Eilif B. Muller, Ph.D.
IVADO Assistant Research Professor
Department of Neurosciences, Faculty of Medicine, University of Montreal
Associate Faculty Member – Quebec Artificial Intelligence Institute (Mila)
Centre de recherche du CHU Sainte-Justine
3175 Côte Sainte-Catherine,
Montréal QC
H3T 1C5, Canada

Graduate Study Opportunity in Insect Neuroethology – University of Manitoba

The Invertebrate Neuroethology Laboratory in the Department of Biological Sciences at the University of Manitoba is seeking one or two talented MSc or PhD students starting in the Fall term of 2021. Our laboratory is interested in how brains select appropriate behavioural responses to varying conditions, how different brains produce different behaviours, and how brains change with age and experience. Using primarily honey bees and cockroaches, we employ immunohistochemistry, microscopy, electrophysiology, and a wide variety of behavioural assays.

Application deadline for Canadian and US applicants: June 1, 2021.
Application deadline for international applicants: March 1, 2021.

For more information, please contact Dr. Byron N. Van Nest at least two months prior to these deadlines.

Contact information

Dr. Byron N. Van Nest
Assistant Professor
Invertebrate Neuroethology Laboratory
Department of Biological Sciences
University of Manitoba
212B Biological Sci Bldg
Winnipeg, MB, R3T 2N2
Canada

byron.vannest@umanitoba.ca

Posting end date

2021/05/01

Graduate positions (PhD/MSc) in Pain Neuroimmunology and Chronobiology | Ghasemlou lab at Queen’s University

The Pain Chronobiology & Neuroimmunology lab (www.ghasemloulab.ca) is seeking applications from outstanding candidates interested in pursuing PhD studies in neuroimmunology and pain physiology. We use animal models of postsurgical pain, chronic neuropathy, spinal cord injury, multiple sclerosis, and Lyme disease, and also studies changes in people living with chronic pain. Current projects include:

  • Neuro-immune control of dendritic cell activation in post-operative pain
  • Peripheral and central neuroinflammation in chronic Lyme disease pain
  • Identifying biomarkers of chronic low back pain using RNA-Seq

Projects in our lab seek to dissect mechanisms underlying interactions between the nervous and immune systems, with a focus on pain. All PhD projects will span clinical (human) and preclinical (mouse) studies, and will use a wide spectrum of approaches, including animal behavior, micro-surgery, molecular biology (flow cytometry, RNA/protein work, immunofluorescence, cell culture), and genetically-modified mouse models. Self-motivated individuals with background (BSc, MSc) in a relevant field (neurosciences, immunology, circadian biology, epidemiology) are encouraged to apply.

Candidates must be creative, capable of working independently and in groups, and will be expected to analyze data and write manuscripts. Interested candidates should send a brief cover letter, CV, transcripts, and

names/contact details of at least one reference to Dr. Nader Ghasemlou at nader.ghasemlou@queensu.ca. Preference is given to Canadian residents/citizens.

Please visit ghasemloulab.ca for an overview of the lab.

Contact information

Please send all relevant materials to Dr. Nader Ghasemlou at nader.ghasemlou@queensu.ca

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Graduate student position: Influence of dopaminergic signals on motor plasticity and recovery – EthierLab – Université Laval

The laboratory of Dr. Christian Ethier is currently recruiting graduate students at the masters or PhD levels for a research project in the field of motor neuroscience to begin during the fall 2020 or winter 2021 semesters.

The goal of this project is to investigate the potential of dopaminergic signals to drive neuronal plasticity and promote motor recovery in rat models of stroke. The project will involve behavioural training, surgical injections and implants, optogenetics and immunohistochemistry, and will take place in the dynamic CERVO Brain Research Center.

Applicants from diverse scientific background will be considered, including engineering, biology and neurosciences. Priority will be given to students with knowledge or skills in:

  • Systems neuroscience
  • Motor system (cortex, basal ganglia, spinal cord function and anatomy)
  • Programming (Matlab, Python, C/C++)
  • Neural plasticity
  • Rodent behavioral tests
  • Dopaminergic systems and function
  • Chronic implants, rodent surgical skills
  • Electrical, optogenetic stimulation
  • Immunohistochemistry, RNAscope, Fluorescence imaging

Contact information

To apply or obtain further information, please send your CV, a motivation letter, and the name of 3 references to Christian Ethier directly: christian.ethier@fmed.ulaval.ca.

Posting end date

2020/09/25