Program 2018 Meeting

Saturday, May 12, 2018

8:00AM – 6:30 PM

CAN Satellite Symposium 5: Neural Signal and Image Processing: Quantitative Analysis of Neural Activity (at Center for Brain Health – University of British Columbia)

4:00 – 6:00PM

Canadian Association for Neuroscience 2018 Public Lectures at Telus Science World

Speakers :

Catharine Winstanley, PhD
Associate Professor, Department of Psychology, University of British Columbia

Against the odds: insights into the nature of addiction from studying decision making in rats

Dr Luke Clark
Director, Centre for Gambling Research at UBC
Department of Psychology

Deconstructing the modern slot machine: gambling, game features and addiction

More information and tickets here

6:00 – 7:00 PM

Satellite 2 Keynote open lecture at Sheraton Wall Centre
Giovanni Marsicano, U Bordeaux
Cannabinoid CB1 receptor signalling in the brain: the where matters

Sunday, May 13, 2018

All events at Sheraton Wall Centre, unless specified.

9:00 AM – 4:30 PM	CAN Satellite symposia Satellite 1: Canadian Action and Perception Network (CAPnet) Satellite 2: 6th Annual Canadian Neurometabolic Meeting Satellite 3: Canadian Neurophotonics Platform Satellite 4: Neural stem cells in development and adulthood
4:45 – 5:00 PM	Welcome and Opening Remarks by Lynn Raymond, President of the Canadian Association for Neuroscience
5:00 – 5:15 PM	Plenary address Sam Weiss, Scientific Director of CIHR’s Institute for Neuroscience and Mental Health
5:15 – 6:15	Presidential Lecture: Rick Huganir \| Johns Hopkins School of Medicine Receptors, Synapses and Memory
6:15 – 7:15	Special Lecture: Gordon M. Shepherd \| Yale School of Medicine From microcircuits to neuroenology: the revolutions in olfaction
7:15 – 8:15	Opening Reception

Monday, May 14, 2018

8:30 – 10:15 AM	Plenary symposium 1: The role of cortico-striatal networks in cognition and action Chair: Melvyn Goodale, Western University Speakers: Catharine Winstanley \| UBC Deciphering decision making: exploring the neural systems underlying the evaluation versus employment of cognitive effort in rats Julien Doyon \| Université de Montréal Cortico-Striatal Contributions to Motor Sequence Learning and Consolidation Jessica Grahn \| Western University Striatal role in auditory sequence perception
10:15 – 10:45	Coffee break Posters/exhibits
10:45 – 11:45	Featured Plenary speaker: Rui Costa \| Columbia’s Zuckerman Institute Starting new actions and learning from it
11:45 – 12:00 PM	Brain Star talk Lauran Cole \| Department of Clinical Neurosciences, University of Calgary Clinical characteristics, risk factors, and outcomes associated with neonatal hemorrhagic stroke: a population-based case-control study
12:00 – 1:30	Equity, Diversity and Inclusivity in Neuroscience Workshop (limited attendance, must be pre-registered) Lunch on own
1:30 – 3:00	Parallel symposium 1 \| Tackling Proteinopathies: New Strategies to Identify and Test Drug Targets. Chair: Maxime W. Rousseaux \| Baylor College of Medicine Speakers: Maxime W. Rousseaux \| Baylor College of Medicine Probing the druggable genome for new modulators of α-synuclein levels Jinsoo Seo \| Daegu Gyeongbuk Institute of Science and Technology Modeling Alzheimer’s disease using hiPSC-derived brain cell types and cerebral organoids Jeehye Park \| Sick Kids Hospital Unraveling the role of MATR3 in amyotrophic lateral sclerosis (ALS) Blair R. Leavitt \| University of British Columbia Huntington disease therapies: from bench to bedside Parallel symposium 2 \| Novel insights in the neurobiology of depression Chair: Naguib Mechawar \| Douglas Institute (McGill University) Speakers: Caroline Ménard \| CERVO Brain Research Centre (Université Laval) Social stress induces neurovascular pathology and immune response promoting depression Benoit Labonté \| CERVO Brain Research Centre (Université Laval) Sex-specific transcriptional signatures in human depression Mounira Banasr \| CAMH (University of Toronto) Linking GABAergic, astroglial and synaptic dysfunctions to stress-induced depressive-like endophenotype: importance of astroglial integrity Naguib Mechawar \| Douglas Institute (McGill University) The impact of child abuse on oligodendrocytes and myelination in the human brain Parallel symposium 3 \| Cannabinoid-metabolism interplay in the control of cognition and behaviour Chair: Stephanie Fulton \| Université de Montréal Speakers: Giovanni Marsicano \| University of Bordeaux Hippocampal CB1 receptors control incidental associations Matthew Hill \| University of Calgary Genetic Variance in Endocannabinoid Signaling Modulates Hormonal and Dietary Influences on Feeding and Metabolism Guillaume Ferreira \| University of Bordeaux Obesogenic diet impairs memory through hippocampal endocannabinoid system Stephanie Fulton \| Université de Montréal ABHD6 in the nucleus accumbens as a unique modulator of endocannabinoid tone, energy metabolism and reward Parallel symposium 4 \| Mild Traumatic Brain Injury: Understanding an invisible injury. Chair: Anne Wheeler \| SickKids Hospital Speakers Brian Christie \| University of Victoria Effects of Repeated Concussions in the Juvenile Brain. Richelle Mychasiuk \| University of Calgary The use of telomere length as a biomarker for mild traumatic brain injury (mTBI) in preclinical and clinical populations Cheryl Wellington \| University of British Columbia Advances in the CHIMERA (Closed Head Injury Model of Engineered Rotational Acceleration) platform of experimental traumatic brain injury Sandy Shultz \| Monash University Neurological abnormalities in collision sport athletes with a history of concussion
3:00 – 3:30	Coffee break
3:30 – 5:30PM	Poster session 1 & Exhibits
5:30 – 7:00	Parallel Sessions Careers inside and outside academia Organizer & Moderator: Stephanie Borgland Speakers: Euan Ramsey, PhD. Co-Founder & COO of Precision Nanosystems Orsha Magyar, M.Sc, CHN CEO & Founder, NeuroTrition Steven Wainwright, PhD. Medical Science Liaison for Shire Pharma Canada Science policy session Organizer: Katalin Toth Moderator: Jaideep Bains Invited speakers: Matt Jeneroux, MP, Conservative Shadow Minister of Science Joyce Murray, Liberal MP for Vancouver Quadra Elizabeth May, MP, leader of the Green Party Brian Masse, MP for Windsor West, Critic for Innovation, Science and Economic Development, NDP

7:30 – 9:30	CAN Student Social

Tuesday, May 15, 2018

8:30 – 10:15 AM	Plenary symposium 2 \| Shaping motivational drive: From synapses to circuits to mesoscale responses Chair: Stephanie Borgland \| Hotchkiss Brain Institute Speakers : Stephanie Borgland \| Hotchkiss Brain Institute Synaptic alterations in the lateral OFC with diet induced obesity Rosemary Bagot \| McGill University Neural endophenotypes of stress susceptibility Timothy Murphy \| University of British Columbia High-throughput electrophysiological, behavioral, or social event triggered imaging of mouse mesoscale brain activity
10:15 – 10:45	Coffee break Posters/exhibits
10:45 – 11:45	Featured Plenary speaker: Kay Tye \| MIT Picower Institute for learning and memory Neural Circuits Underlying Positive and Negative Valence
11:45 – 12:00 PM	Brain Star talk Andrew Kaplan \| Montreal Neurological Institute, McGill University Small-molecule modulation of 14-3-3 proteins for axon regeneration
12:00 – 12:30	CAN-ACN Annual General Meeting of members
12:30 – 1:30	Lunch on own
1:30 – 3:00	Parallel symposium 5 \| Synapse to nucleus: new insights into epigenomic, transcriptional, and translational programs underlying neural circuit plasticity Chair: Stefano Brigidi \| University of California San Diego Speakers Iva Zovkic \| University of Toronto Mississauga Histone variants regulate memory formation Wayne Sossin \| McGill University RNA granules consist of stalled polysomes: Exploring mechanisms for their formation Tae-Kyung Kim \| University of Texas Southwestern Activity-dependent gene expression program underlying brain plasticity Stefano Brigidi \| University of California San Diego Communication of pathway-specific circuit activity to the genome by the immediate early gene Npas4 Parallel symposium 6 \| Bridging the gap between mesoscopic and microscopic brain imaging Chair: Ravi Rungta \| French National Institute of Health and Medical Research (INSERM) Speakers Ravi Menon \| Robarts Research Institute, University of Western Ontario Using fMRI to study laminar and columnar activity Ravi Rungta \| French National Institute of Health and Medical Research (INSERM) Linking synaptic activation to hemodynamic signals for functional brain imaging Bojana Stefanovic \| Sunnybrook Health Sciences Centre Neurovascular imaging in health and in Alzheimer’s Disease Matthieu Vanni \| University of British Columbia Neural circuits mapping using mesoscopic calcium imaging in mice Parallel symposium 7 \| Novel molecular targets of Alzheimer’s disease pathology Chair: Hideto Takahashi \| Institut de recherches cliniques de Montréal Chair: Vania Ferreira Prado \| University of Western Ontario Speakers Hideto Takahashi \| Institut de recherches cliniques de Montréal Role of synaptic organizer Neurexin on amyloid β-induced synaptic pathology Vania Ferreira Prado \| University of Western Ontario Role of cholinergic-induced RNA Metabolism change in Alzheimer’s-Like Pathology Jack H. Jhamandas \| University of Alberta Amylin Receptor: A Potential Therapeutic Target for Alzheimer’s Disease Weihong Song \| University of British Columbia Prenatal Vitamin A deficiency facilitates Alzheimer’s pathogenesis Parallel symposium 8 \| Predicting Fear and Safety in the Brain Chair: Mihaela Iordanova \| Concordia University Speakers Gavan McNally \| The University of New South Wales Parsing the amygdala mechanisms for learning Susan Sangha \| Purdue University Effect of safety cues on fear and reward seeking behaviors and its neuronal correlates Michael McDannald \| Boston College Beyond reward: ventral striatal/ventral pallidal contributions to rapid and accurate fear discrimination Mihaela Iordanova \| Concordia University Mesolimbic circuits of aversive prediction error
3:00 – 3:30	Coffee break
3:30 – 5:30	Posters session 2 and Exhibits
5:30 – 6:00	Young investigator lecture Karun Singh \| McMaster University Investigating signaling mechanisms controlling neuronal growth and brain development disorders
6:00 – 7:00	Keynote Lecture: Freda Miller \| University of Toronto Stem cells and growth factors: building and repairing the mammalian nervous system

Wednesday, May 16, 2018

8:30 – 10:15 A.M.	Plenary symposium 3 \| Glia in brain health, disease and repair Chair: Brian MacVicar \| UBC Speakers: Brian MacVicar \| UBC Roles for astrocytes and pericytes in the regeneration of cerebral blood vessels after stroke Michael Salter \| University of Toronto Sex, Pain and Microglia Keith Murai \| McGill University Optimizing Brain Circuit Microenvironments Through Neuron-Astrocyte Communication
10:15 – 10:45	Posters/exhibits Coffee break
10:45 – 11:45	Featured Plenary speaker: Beth Stevens \| Harvard Medical School How the Immune System Sculpts Brain Circuitry
11:45 – 12:00 PM	Brain Star talk Nicole E. Burma \| Hotchkiss Brain Institute, University of Calgary A new use for an old drug: probenecid alleviates opioid withdrawal in rodents
12:00 – 12:15	NSERC funding information session – Mark Shore, PhD, Natural Sciences and Engineering Research Council of Canada Research Grant Program Officer
12:15 – 1:30	Lunch on own
1:30 – 3:30	Posters session 3 & Exhibits
3:30 – 5:00	Parallel symposium 9 \| Time and memory Chair: Sheena Josselyn \| The Hospital for Sick Children Speakers Mary Cheng \| University of Toronto Mississauga miR-132/212 mediates seasonal plasticity of the central circadian clock Qi Yuan \| Memorial University Pheromone communication of odor-specific fear in rats Satoshi Kida \| Tokyo University of Agriculture Time-dependent regulation of memory retrieval by hippocampal clock Mauro Costa-Mattioli \| Baylor College of Medicine New mechanisms underlying memory dysfunction Parallel symposium 10 \| Novel Approaches to Promoting Spinal Plasticity Chair: Ian Winship \| University of Alberta Speakers Wolfram Tetzlaff \| University of British Columbia Cortical Motor Map Plasticity and Functional Recovery via Spared Dorsolaterally Projecting Corticospinal Neurons after Spinal Cord Injury Alyson Fournier \| McGill University Small Molecule Stabilization of 14-3-3 Protein-Protein Interactions to Promote Axon Regeneration Karim Fouad \| University of Alberta Eliciting inflammation enables successful rehabilitative training in chronic spinal cord injury Ian Winship \| University of Alberta Enhancing Spinal Plasticity to Improve Recovery from Cortical Stroke Parallel symposium 11 \| Mechanisms underlying brain dysfunction in Alzheimer’s disease Chair: Doug Munoz \| Queen’s University Speakers Marco A.M. Prado \| Western University Crossing the translational gap in Alzheimers disease research Fernanda G. De Felice \| Queen’s University Molecular connections between Alzheimers disease and Type 2 diabetes Isabelle Aubert \| University of Toronto Alzheimers Disease: Vascular and Neuronal Plasticity Douglas P. Munoz \| Queen’s University Biomarkers of disease progression in a non-human primate model of Alzheimers Disease Parallel symposium 12 \| Development and function of motor circuits: from hardwired patterning to functional maturation and sensory integration. Chair: Artur Kania \| IRCM (Institut de recherches cliniques de Montreal) Speakers Douglas W. Allan \| University of British Columbia Target-dependent gene activation in neurons is mediated by widespread deployment of a BMP-responsive cis-regulatory element. Angelo Iulianella \| Dalhousie University Taming the gradient: the intrinsic regulation of Sonic Hedgehog signaling in the specification of ventral cell identities in the developing spinal cord Tuan Vu Bui \| University of Ottawa A switch in the mode of operation of spinal locomotor networks in the developing zebrafish Tomoko Ohyama \| McGill University Circuit mechanism underlying a Drosophila larval escape sequence
End of Meeting

Program 2018 Meeting

Against the odds: insights into the nature of addiction from studying decision making in rats

Deconstructing the modern slot machine: gambling, game features and addiction

Receptors, Synapses and Memory

From microcircuits to neuroenology: the revolutions in olfaction

Starting new actions and learning from it

Equity, Diversity and Inclusivity in Neuroscience Workshop

1:30 – 3:00

Parallel symposium 1 | Tackling Proteinopathies: New Strategies to Identify and Test Drug Targets.

Parallel symposium 2 | Novel insights in the neurobiology of depression

Parallel symposium 3 | Cannabinoid-metabolism interplay in the control of cognition and behaviour

Parallel symposium 4 | Mild Traumatic Brain Injury: Understanding an invisible injury.

Careers inside and outside academia

Science policy session

Plenary symposium 2 | Shaping motivational drive: From synapses to circuits to mesoscale responses

Neural Circuits Underlying Positive and Negative Valence

Parallel symposium 5 | Synapse to nucleus: new insights into epigenomic, transcriptional, and translational programs underlying neural circuit plasticity

Parallel symposium 6 | Bridging the gap between mesoscopic and microscopic brain imaging

Parallel symposium 7 | Novel molecular targets of Alzheimer’s disease pathology

Parallel symposium 8 | Predicting Fear and Safety in the Brain

Investigating signaling mechanisms controlling neuronal growth and brain development disorders

Stem cells and growth factors: building and repairing the mammalian nervous system

Plenary symposium 3 | Glia in brain health, disease and repair

How the Immune System Sculpts Brain Circuitry

3:30 – 5:00

Parallel symposium 9 | Time and memory

Parallel symposium 10 | Novel Approaches to Promoting Spinal Plasticity

Parallel symposium 11 | Mechanisms underlying brain dysfunction in Alzheimer’s disease

Parallel symposium 12 | Development and function of motor circuits: from hardwired patterning to functional maturation and sensory integration.