Alzheimer’s disease : It takes two (proteins) to tango

Pedro Rosa-Neto
Pedro Rosa-Neto

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

In the journal Molecular Psychiatry, the team led by Dr. Pedro Rosa-Neto, a clinician scientist at the Douglas and assistant professor of Neurology, Neurosurgery and Psychiatry at McGill University, reports for the first time evidence that the interaction between amyloid and tau proteins drives brain damage in cognitively intact individuals. Continue reading

Canadian Researchers Help To Understand How The Brain Copes With Stress

It’s one of the guarantees of life: stress. At its core, it’s a perception of a physical or psychological threat and is designed to help us survive. But the triggers are varied and as such, there is no single way to deal with the impending sensation of harm.
For years, researchers have studied the stress spectrum and identified numerous behavioural changes. Most are relatively simple to understand such as heightened awareness, risk avoidance, and the fight or flight response. Continue reading

Researchers Are Learning How The Brain Tells Us To Stop Moving

In the playground, a popular game for kids of all ages is “Freeze.” The concept is rather simple. A leader tells the participants they are free to move around until everyone is told to freeze in place. Those who don’t suddenly stop are notified they are out and the game continues. It’s a great way to learn how to deal with environmental stimuli and also how to better control locomotor abilities. But most of all, it’s a great deal of fun. Continue reading

University of Ottawa Researchers Have Found A New “Fate” For Aging Stem Cells

Death is a normal part of the life cycle for cells. They form, grow, perform their expected duties and then, after a while, face a predictable fate. When the time comes, the cell undergoes a programmed process, known as apoptosis http://www.ncbi.nlm.nih.gov/books/NBK26873/  to break down many of the internal components and pave the way for the final end. Continue reading

McGill Researchers May Have Discovered the Neurological Basis For An Eye-Catching Mystery

People usually find it easier to see things when they are big and bright, but there are occasionally exceptions. One example concerns moving objects: when they are small, we can identify their direction of motion easily. But this becomes much more difficult for larger objects. This phenomenon is known as spatial suppression http://www.nature.com/nature/journal/v424/n6946/full/nature01800.html. Continue reading

Brain cells that aid appetite control identified

Maia Kokoeva
Maia Kokoeva

Discovery opens door to development of new drugs to control weight gain and obesity
It’s rare for scientists to get what they describe as “clean” results without spending a lot of time repeating the same experiment over and over again. But when researchers saw the mice they were working with doubling their weight within a month or two, they knew they were on to something. Continue reading