Dr. Sangyoon Ko is the winner of the Marlene Reimer Brain Star of the year prize, a the first place winner of 2025.
New research reveals that memories continue to evolve in the brain
Memory consolidation is the process through which initially fragile memories are transformed into long-term, more stable forms of memory. For decades, neuroscience textbooks have described this process as a gradual transfer of memories from the hippocampus—where memories are first encoded—to the neocortex for permanent storage. Findings by Dr. Sangyoon Ko and colleagues in the Josselyn-Frankland laboratory at The Hospital for Sick Children (SickKids) in Toronto now reveal a far more dynamic process.
View the original research publication:
Sangyoon Y. Ko, Yiming Rong, Adam I. Ramsaran, Xiaoyu Chen, Asim J. Rashid, Andrew Mocle, Jagroop Dhaliwal, Ankit Awasthi, Axel Guskjolen, Sheena A. Josselyn, Paul W. Frankland (2025). Systems consolidation reorganizes hippocampal engram circuitry. Nature, 643(8072), 735-743.
