Category: News
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A study by Martin Lévesque and his team explains the role of dopaminergic neurons in hyperactivity and suggests a mechanism of action for Ritalin
Read a new article by Université Laval news on a discovery by Martin Lévesque’s team Cellular cogs of hyperactivity uncovered – Study clarifies the role of dopaminergic neurons in hyperactivity and suggests a mechanism of action for Ritalin The cellular mechanism uncovered by the researchers could explain the mode of action of Ritalin in humans. The…
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McGill researchers end decade-long search for mechanical pain sensor
Discovery brings hope for novel pain treatment Researchers at McGill University have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new analgesic drugs. The study, published in Cell, is the first to show that…
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Pain hypersensitivity: problem at the pump
Pain hypersensitivity and many other diseases could be associated with a protein that acts as an ion pump in neurons. The research team led by Yves De Koninck, at Université Laval’s Faculté de médecine and the CERVO Brain Research Centre had already targeted a protein called KCC2 as a key player in the mechanism leading to…
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Canadian Interns Contribute to the Success of the 13th CAN-IBRO Summer School
Dr. Claire Bomkamp (UBC) and Ms. Jennifer Boateng (McGill) participated as Teaching Interns for the 13th CAN-IBRO school held from May 13-31, 2019 in Montreal and Toronto. The two interns contributed to the teaching of 6 African and 6 Latin American graduate students and postdoctoral fellows and found it a great experience.
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New CAN newsletter
Read our latest news in CAN Connection – Winter 2020
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Researchers first to use ultrasound to deliver a compound that stimulates brain cell communication in mice with Alzheimer’s disease
Sunnybrook Research Institute senior scientist Dr. Isabelle Aubert and her PhD student, Kristiana Xhima, led the first study using focused ultrasound to deliver a molecule to the brain to revive the function of neurons vital to learning and memory in mice with Alzheimer’s disease. Breakthrough targets restoring the function of neurons vital to learning and…
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Slowing the progression of multiple sclerosis
By identifying a molecule that delays the progression of MS, CRCHUM researchers pave the way for new therapies for the nearly 77,000 Canadians living with the disease. Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure. In a study published in…
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Cellular origins of pediatric brain tumors identified
Source: MUHC and Lady Davis Institute A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre (RI-MUHC), and Dr. Michael Taylor, of The Hospital for Sick Children (SickKids), discovered that…
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Activation of opioid receptor uncovered
In conjunction with Chinese, Belgian, German and American academic colleagues, the team of researchers from the Université de Sherbrooke (UdeS), led by the Director of the Department of Pharmacology-Physiology, Professor Louis Gendron, participated in the discovery of the binding mechanism of an important opioid receptor. The results should facilitate the development of new active substances.…
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Patients with mood, anxiety disorders share abnormalities in brain’s control circuit
Dr. Sophia Frangou was recently appointed UBC President’s Excellence Chair in Brain Health. New research published recently in JAMA Psychiatry shows for the first time that patients with mood and anxiety disorders share the same abnormalities in regions of the brain involved in emotional and cognitive control. The findings hold promise for the development of new treatments targeting…