Katalin Toth - Alyson Fournier new CAN executives Tuan Trang and Mike Sapieha - CAN Young Investigator winners for 2017 Canadian Neuroscience Research luncheon in Parliament Montreal 2017 impact of neurological disorders in Canada

 

CAN-ACN news

McGill Researchers Have Found A Possible Path For Treatment of Fragile X Syndrome

There is no denying autism spectrum disorders, commonly known as ASD, have become some of the world’s greatest health concerns. But what most people do not know is the incredible complexity of these conditions. As researchers have found, the problems are not singular in nature. Rather, they are a consequence of several changes in the way the cells of the brain function. This reality has forced ASD researchers to head deep into the molecular level of the brain in the hope of understanding what is happening in those affected.

Researchers at Dalhousie University Reveal A Startling Phenomenon in Evolution

Have you ever been startled by a sudden noise, sight or touch? It can be quite a shock to the system. You tense up, your mind blanks out all previous thoughts, and you find yourself preparing for the worst. Then there are the lingering effects that can last for minutes after it is all over. While you may hate the feeling of being startled, neuroscience researchers have found the entire process is a natural part of life inherited in evolution from our ancient ancestors.

Neuroscience news

Brain area involved in addiction activated earlier than previously thought in recreational cocaine users

Marco Leyton

Marco Leyton

Non-dependent users also experience dopamine release in response to drug cues

Even among non-dependent cocaine users, cues associated with consumption of the drug lead to dopamine release in an area of the brain thought to promote compulsive use, according to researchers at McGill University.

The findings, published in Scientific Reports, suggest that people who consider themselves recreational users could be further along the road to addiction than they might have realized.

Common acne medication offers new treatment for multiple sclerosis – Study results offer safe and affordable treatment option

Luanne Metz and  V. Wee Yong

Luanne Metz and V. Wee Yong

A Canadian clinical trial led by researchers at the University of Calgary’s Hotchkiss Brain Institute (HBI), at the Cumming School of Medicine (CSM), shows that minocycline, a common acne medication, can slow the progress of relapsing-remitting multiple sclerosis (MS) in people who have recently experienced their first symptoms.

In addition to being an unexpected discovery — an acne drug benefitting a neurological disorder — the discovery is significant as it offers a safe and affordable treatment option for those with early onset MS. This discovery could impact thousands of newly diagnosed MS patients around the world.

Researchers identify specific neurons that distinguish between reality and imagination

Julio Martinez-Trujillo

Julio Martinez-Trujillo

New Western University research shows that neurons in the part of the brain found to be abnormal in psychosis are also important in helping people distinguish between reality and imagination.

The researchers, Dr. Julio Martinez-Trujillo, principal investigator and professor at Western University’s Schulich School of Medicine & Dentistry and Dr. Diego Mendoza-Halliday, postdoctoral researcher at M.I.T., investigated how the brain codes visual information in reality versus abstract information in our working memory and how those differences are distributed across neurons in the lateral prefrontal cortex region of the brain. The results were published today in Nature Communications (https://www.nature.com/articles/ncomms15471)

Researchers identify a new factor essential for the healthy development of a child’s brain

Freda Miller

Freda Miller

Proper brain development is a crucial step in a child’s health. An important part of brain development is the creation of white matter, which enables different regions of the brain to rapidly and effectively “talk” to one another.

In a new study published in Neuron, a team of researchers led by Dr. Freda Miller and Dr. David Kaplan has revealed how oligodendrocytes, which are crucial for proper brain function and that are damaged or altered in conditions such as Multiple Sclerosis, autism and concussions, are formed during development.

Molecule shown to repair damaged axons

Alyson Fournier

Discovery could be key to treating brain and spinal cord injury

A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.

Andrew Kaplan, a PhD candidate at the Montreal Neurological Institute and Hospital of McGill University, was looking for a pharmacological approach to axon regeneration, with a focus on 14-3-3, a family of proteins with neuroprotective functions that have been under investigation in the laboratory of Dr. Alyson Fournier, professor of neurology and neurosurgery and senior author on the study.

Second study from UBC shows “liberation therapy” fails to treat multiple sclerosis

Anthony Traboulsee

Anthony Traboulsee

Opening up narrowed veins from the brain and spinal cord is not effective in treating multiple sclerosis (MS), according to a study led by the University of British Columbia and Vancouver Coastal Health.

The conclusions about so-called “liberation therapy,” which thousands of people with MS have undergone since 2009, represent the most definitive debunking of the claim that MS patients could achieve dramatic improvements from a one-time medical procedure.