NIH Funded post-doctoral position to study neuropathological changes of brain trauma in athletes. Candidate should have good knowledge of neuropathological work-up of neurodegenerative diseases in human brains. Project plans to explore and report on all neuropathological changes in a brain bank.
Contact information lili-naz.hazrati@sickkids.ca
Category: Trainee opportunities
A post-doc position in the field of neural stem cell reprogramming and differentiation, Wang lab, Ottawa Hospital Research Institute
Description of the position:
Our research focuses on delineating molecular mechanisms that regulate neural stem cell reprogramming and differentiation, with the ultimate goal of the development of stem cell- based therapy to promote neural repair in the context of various neurological disorders. The individual filling this position is particularly involved in the ongoing project in the lab that is to develop integration-free methodology to reprogram non-neuronal cells into neural cells and to optimize stem cell-based therapies for post-stroke neurovascular regeneration and functional recovery. A variety of molecular, cellular, and behavioral techniques are used in the laboratory, including transgenic mouse models, neurosphere culture, rodent and human reprogramming cell culture and stereotaxic surgery, various neurological degeneration disease models, etc.
Eligibility Requirements:
- Experience in rat stroke models, stereotaxic surgery, Cell Biology (cell line or primary cell culture, immunohistochemistry and immunocytochemistry) and in vivo animal study.
- Excellence in research with strong publication records
- Excellent written and oral communication skills
- Self-motivated and strong desire to learn
- Experience with Human primary cell culture is an asset
Deadline: Until the position is filled.
Individuals who are interested in the position should submit curriculum vitae, a copy of official transcripts, statement of research interest and names of three references to:
jiwang@ohri.ca
Dr. Jing Wang, Ph.D.
Senior Scientist, Sprott Centre for Stem Cell Research
Ottawa Hospital Research Institute
Assistant Professor Department of Cellular & Molecular Medicine
University of Ottawa
Ottawa Hospital, 501 Smyth Rd, Box 511
Ottawa, ON K1H 8L6 CANADA
Postdoctoral Researcher in Computational Neuroscience – Lefebvre lab at UOttawa
The Lefebvre lab at uOttawa is recruiting two postdoctoral fellows for the Winter 2020. Candidates interested in computational neuroscience, brain imaging and applied mathematics are encouraged to apply.
Selected candidates will be involved in the following projects:
- In collaboration with the Griffiths Lab at the CAMH Krembil Center for Neuroinformatics (KCNI) and University of Toronto, the goal of the project is to develop, analyse and explore computational models of non-invasive brain stimulation (e.g. TMS, TES) and their impact on multi-scale neural activity. Specifically, we seek to better understand network-based mechanisms of neural control, oscillatory entrainment and/or stimulation-induced brain plasticity. This project involves a combination of computational and mathematical modelling, has strong potential for knowledge translation, and aims to help inspire new non-invasive treatments for Major Depressive Disorder (MDD).
- In collaboration with the Hospital for Sick Children (SickKids) in Toronto, the goal of this project is to better understand mechanisms of white matter plasticity, neuron-glia interactions, myelination and its impact on brain function. Using a combination of modelling and simulations, interfacing rodent and human data, the role of the fellow will be to examine the influence of white matter plasticity on neural synchrony and memory. This project involves a combination of computational and mathematical modelling, and strong interactions with experimentalists.
The research will take place in the Department of Biology, the Brain and Mind Institute and the Center for Neural Dynamics of the University of Ottawa, a vivid interdisciplinary research cluster set in the bilingual capital of Canada. Both projects are deployed in the Ottawa-Toronto axis, through close collaborations between uOttawa, uToronto, CAMH KCNI, The University Health Network and The Krembil Research Institute. Based on the research needs and resources, candidates will be required to travel between both cities often. Throughout, candidates will interact closely with clinicians, experimentalists and scholars in neuroimaging.
Requisites:
Candidates should have completed their PhD in physics, mathematics, neuroscience or related disciplines, and have an excellent publication track record. Expertise in programming is a necessity, as well as independence in research. Experience in brain imaging, signal processing and dynamical systems are considered strong assets. Contracts are for one year, with possibility of extension subject to sufficient progress. of one additional year. While the positions are fully funded, candidates are nonetheless expected to apply for external/competitive funding throughout their training.
To apply, please send 1) a letter of interest, 2) a full CV and 3) two(2) letters of reference to jeremie.lefebvre at hotmail dot com. Selected candidates will be contacted for an interview! Job open until filled!
2 Post-doc positions in clinical and cognitive neuroimaging MRI/DTI and EEG/MEG – SickKids Hospital
Neurophysiological and structural imaging in PTSD and mild traumatic brain injury
Two postdoctoral research fellow positions at the Hospital for Sick Children (SickKids) are available with immediate start. The positions are initially available for a 1-year period with the possibility of extension.
This project examines functional (MEG, fMRI) and structural (MRI, DTI) brain circuits in posttraumatic stress disorder and mild traumatic brain injury (concussion) in adults. Currently, there are no known imaging markers for psychiatric disease or ‘mild’ brain injuries. This project aims to define signatures for use in a machine learning framework to classify individual cases and identify future targets for neurostimulation in treatment-resistant cases of PTSD and those with lingering symptoms of a concussion.
This is part of an ongoing project that is funded by the Canadian Department of National Defence and Innovation for Defence, Excellence and Security (IDEaS) Program.
A substantial amount of data already exists for this project and the motivated researcher will be able to jump straight into analysis.
Your profile
We are seeking two enthusiastic postdoc researchers to work in close collaboration with engineers and research associates in analysing pre-existing and new MEG, MRI & DTI data. Ideally, one researcher will focus on MRI and DTI data, and the other one MEG data, the latter collected during resting state and a task of memory function. Given the initial short-time frame of this position, imaging experience is necessary.
As a postdoc in this position you will be expected to:
- hold a PhD in a relevant area (cognitive neuroscience, neuroimaging, engineering, computer sciences);
- have experience with EEG/MEG and/or MRI/DTI analyses;
- have a knowledge of neuropsychiatric disease that would be advantageous;
- hold a track record in research commensurate with your level of experience post-PhD;
- have experience with computer programming (Matlab, Python, or R) and/or signal processing/time series analyses;
- have excellent communication skills (oral and written);
- be able to work independently and meet deadlines.
Your work environment
The principal investigator on this project is Dr. Ben Dunkley.
The candidate will be based in the Neurosciences & Mental Health Program, the Hospital for Sick Children Research Institute. You will work closely with affiliated staff and students who form a group that use neuroimaging to study a variety of brain disorders.
We offer
Salary Scale: $CAD 55,000 to 65,000 gross annual (depending on qualifications and experience).
In addition, we offer an attractive benefits package, that includes partial coverage for dental, drug and medical.
The temporary employment will be for a period of 1 year initially, with a possibility of extension.
Toronto is a world-class rated in the top ten cities worldwide for livability that has a large and rich neuroscience community.
The institute offers many opportunities for career development and additional training as part of the Research Training Centre.
Additional information
The post is available from 1st January 2020.
Contact Dr. Ben Dunkley via ben.dunkley@sickkids.ca for more information.
If you wish to apply directly, please send a CV, a cover letter with research statement/interests, and the names of two references.
Post-doctoral position – Dr. Junchul Kim lab in Psychology/Cell and Systems Biology Department in the University of Toronto
A funded postdoctoral fellow position is available (start date is negotiable) at Dr. Junchul Kim lab in Psychology/Cell and Systems Biology Department in the University of Toronto, Canada. The lab uses optogenetics, chemogenetics, intersectional viral tools, and calcium imaging to understand neural circuits underlying memory in mice. The selected candidate will also participate in collaborative projects for investigating working memory, anxiety, and escape behaviours. A strong understanding of behavioral neuroscience is desired.
Specific skills and qualifications for the position include:
- PhD in Neuroscience, Physiology, Psychology, or a related field.
- Experience with stereotaxic surgery.
- Experience with mouse behavioral tests.
- Experience with in vivo calcium imaging is desirable.
- Experience with molecular biology is encouraged but not a requirement.
Salaries will be in line with University of Toronto postdoctoral stipend levels. To apply, please send curriculum vitae, a brief statement of research experience and interests, and letters of reference to Dr. Junchul Kim (kim@psych.utoronto.ca). Please also visit our website to learn more about the lab: www.junchulkimlab.com
Contact information
Junchul Kim
100 St.George st, Room 4028.
Department of Psychology, University of Toronto,
Canada,
M5S3G3
Phone 1-416-578-8319
Email: kim@psych.utoronto.ca
Website
Postdoctoral Position in Systems Neuroscience – University of Toronto Scarborough
The Arruda-Carvalho lab is looking for a highly motivated applicant to lead a collaborative, HFSP-funded project focusing on the neural mechanisms of fear generalization in mice. The project will include experiments spanning behaviour, slice electrophysiology, stereotaxic surgery, fiber photometry and optogenetics. The project is part of a collaborative grant with the Grewe lab in the University of Zurich and the Kheirbeck lab at UCSF.
We are looking for applicants with a PhD in neuroscience, biology, psychology or closely related field. Experience with rodent research is necessary. Experience with slice electrophysiology (whole cell patch clamping) and stereotaxic surgery is wanted but not a requirement.
Please visit our lab website to learn more about our group: https://devsneurolab.com/
Contact information All individuals interested in this position must submit a CV, statement of interest and a list of references to m.arrudacarvalho@utoronto.ca
Download a pdf version of this advertisement:
Postdoctoral Scholar to join a neurovascular imaging laboratory at University of Nevada
The University of Nevada, Reno School of Medicine Department of Physiology & Cell Biology is currently seeking a postdoctoral fellow to join a neurovascular imaging laboratory. The applicant will have a deep understanding of the neurovascular coupling and cerebral blood flow regulation.
The successful applicant will be responsible for conducting independent experiments that involve delicate surgeries, complex pharmacological manipulations and highly technical imaging. The ideal candidate has extensive knowledge of vascular biology and/or neuroscience. The incumbent will be required to write manuscripts with guidance from the principal investigator, and present data at national and international conferences. The position requires great technical skills, ability to adapt, troubleshoot experimental protocols, and some scientific creativity. Some computer skills, including Matlab, are highly recommended.
Our lab utilizes two-photon laser scanning microscopy (TPLSM) to understand how neural cells communicate with vascular cells in order to regulate blood flow to match with metabolic demands. The unique strengths of our approach include state-of-the art TPLSM, awake in vivo mouse model, and advanced techniques including optogenetics, chemogenetics. In addition, we use complementary in vitro models to probe different physiological parameters to understand the interaction among members of the neurovascular unit. We are also interested in uncovering how local signals are integrated to globally regulate blood flow distribution to match moment-to- moment brain activity.
Required Qualifications
The successful candidate will have a recent PhD in vascular biology or neuroscience. The candidate has the ability to troubleshoot complex technical experiments and change procedures as required. Ability to work independently and in a collaborative environment is needed. The candidate also needs to be able to think critically about the projects. Experience in working with animal models is necessary. Good written and verbal communication skills are a must.
Preferred Qualifications
Ability to perform in vitro and/or in vivo experiments is highly desired. Experience in imaging and/or electrophysiology is recommended. Solid publication record is a plus.
Department Information
Our Department ranks highest in extramural research funding among the Departments of the School of Medicine at the University of Nevada, Reno, as well as in the number of scientific articles published. The Department contributes to several NIH-funded Program grants such as Centers of Biomedical Research Excellence (“COBREs”) Smooth Muscle and Cell Biology, IDeA Network of Biomedical Research Excellence (INBRE) and Program Project Grant (PPG) in its 23rd year.
Contact information Department Contact
Cam Ha Tran, PhD
Assistant Professor, University of Nevada, Reno, School of Medicine, Dept. of Physiology & Cell Biology
camt@med.unr.edu Office: 775-682-9830
Website: https://med.unr.edu/cobre-mcstcs
Postdoctoral Position: Examining differences in neural profiles in males & females with EEG+fMRI – University of Ottawa
The Lab
Clinical EEG & Cognitive Research Laboratory, Institute of Mental Health Research, affiliated with the University of Ottawa (Ottawa, ON, Canada).
https://eeglab-imhr.weebly.com/
https://uniweb.uottawa.ca/members/3376
Our laboratory uses clinical electroencephalography (EEG) and neuroimaging techniques (e.g. functional magnetic resonance imaging), coupled with various clinical and cognitive assessment tools, to better understand mental illness. We also assess the effects of various interventions (e.g. exercise, stimulation therapies, drugs) on neural, clinical and cognitive features. Importantly, we attempt to characterize neural profiles that may be predictive of treatment response. Much of our laboratory’s work has focused on depression. However, we also examine brain features in individuals with schizophrenia, ADHD, dysfunctional anger as well as non-psychiatric populations.
The Position
The postdoctoral fellow will be tasked to conduct an NSERC-funded research study examining gender differences in neural profiles between males/females using simultaneous EEG+fMRI. Neural features will be examined in relation to biological measures (estrogen, testosterone and cortisol).
The selected postdoctoral fellow will also have an opportunity to assist in the acquisition/data analyses on one of two projects in clinical samples (depressed, schizophrenia). Within this role, he/she will be expected to assist Dr. Jaworska in the mentoring of undergraduate and graduate students in the laboratory, in manuscript preparation and in grant writing.
Academic qualifications and requirements
- PhD in neuroscience, psychology, biomedical science or related disciplines.
- Demonstrated experience in human research and/or cognitive or computational neuroscience.
Required: Neuroimaging analyses (preferred: SPM, CONN) or EEG analyses. Some computational neuroscience experience preferred.
Optimal: Experience in simultaneous EEG+fMRI acquisition & analyses.
Timeline and application process
Application deadline: open until the position is filled
Fellowship start date: Late fall 2019
Submission process: Documents should be emailed to Dr. Natalia Jaworska (natalia.jaworska@theroyal.ca)
Application checklist:
- A one (1) page research statement demonstrating fit with the program described above.
- Current academic CV demonstrating research excellence and a capacity for leadership in the domain.
- Contact information for two references from academic supervisors /current employers.
Value
The Postdoctoral Fellowship is a stipend valued at a starting salary of $40,000 per year, commensurate on experience and availability of funds. Duration: 1 year (extension will be contingent upon both funds availability and performance).
Contact information Documents and/or questions should be emailed to Dr. Natalia Jaworska (natalia.jaworska@theroyal.ca)
Multiple Postdoc Positions – Computational and Systems Neuroscience of Recurrence and Dendritic Integration – Centre for Neural Dynamics of the University of Ottawa
Multiple theoretical, computational and experimental neuroscience postdoctoral positions are available immediately at the Centre for Neural Dynamics of the University of Ottawa.
Position 1: Theoretical neuroscience and nonlinear/statistical physics focusing on the dynamics of a population of core recurrent neurons within the hippocampus and their role in temporal and spatial memory. The candidate will be involved in collaborations between Profs. Len Maler, André Longtin and Jean-Claude Béïque.
Position 2: Experimental and computational neuroscience focusing on dendritic integration. Expertise in cellular electrophysiology and/or computational neuroscience is an asset. The candidate will be involved in collaborations between Profs. Richard Naud and Jean-Claude Béïque.
Position 3: Computational and experimental neuroscience focusing on dendritic integration and recurrent circuitry. Expertise in cellular electrophysiology and/or computational neuroscience is an asset. The candidate will be involved in collaborations between Profs. André Longtin, Richard Naud, Jean-Claude Béïque and Len Maler.
The researcher will join uOttawa’s Brain and Mind Research Institute’s Center for Neural Dynamics. uOttawa’s Neuroscience community is fast expanding, highly dynamic and offers a rich array of collaborative opportunities. Ottawa, the capital of Canada, is a green, multi-cultural city that offers the highest standard of living in the country and is second worldwide for quality of life (Numbeo index, 2015). The city has many parks including the UNESCO World Heritage Rideau Canal, and is surrounded by an extensive greenbelt and the vast Gatineau Park twenty minutes away. This bilingual, safe and culturally-rich city lies along the border between the provinces of Ontario and Québec, is a few hours of driving away from Montréal and Toronto and served by an international airport.
Each position is for one year with automatic renewal for a second year following satisfactory progress, and a possible extension to a third year. Interested candidates should submit their CV and a brief statement of research interests to alongtin@uottawa.ca . The successful candidate would be a salaried employee of the University with a competitive remuneration and benefits package.
Contact information: alongtin@uottawa.ca
Posting end date: 2019/12/31
Post-Doctoral Fellow (Mouse Models) – Western University, London ON – Saksida Bussey labs
Two Post-Doctoral Positions Available:
Two postdoctoral position are available immediately under the supervision of Dr. Lisa Saksida and Dr. Tim Bussey at the Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario. The positions will focus on questions related to molecular and cellular mechanisms of information storage mainly in the hippocampus. The project will involve recording neuronal activity using miniscopes and fibre photometry, manipulating circuits with DREADDs and optogenetics, and integration of these techniques with sophisticated analysis of high-level cognition.
Cognitive neuroscience in health and disease is a major research focus at Western, which is currently supported by BrainsCAN, a $66M Canada First Research Excellence Fund grant awarded to Western in 2016. The Robarts Research Institute and the Brain and Mind Institute together create a vibrant neuroscience research community with many opportunities for collaborations. The University of Western Ontario (www.uwo.ca) is a major educational and research center in Ontario with over 25,000 undergraduate and 5,000 graduate students. London, also known as the Forest City, is an affordable and lively community close to the Great Lakes and two hours from Toronto. The city offers many options for outdoor and cultural activities.
Qualified applicants should have a PhD degree in Neuroscience or related disciplines with significant expertise in studying mouse models. Prior experience in mouse surgery, fibre photometry, optogenetics, DREADDs, in vivo electrophysiology, data analysis using MATLAB, Python and/or R, documented in peer-reviewed publications will be an asset. We are looking for two highly-motivated individuals within 2 years of receiving a PhD. Salary will be paid commensurate with experience.
Western is committed to employment equity and diversity in the workplace and welcomes applications from women, members of racialized groups/visible minorities, Aboriginal persons, persons with disabilities, persons of any sexual orientation, and persons of any gender identity or gender expression.
Contact information Please send a statement of interest, Curriculum Vitae, and the names of at least two references to:
Dr. Lisa Saksida & Dr. Tim Bussey,
Robarts Research Institute, University of Western Ontario
Email: tcnlab@uwo.ca
TCNLab: http://www.tcnlab.uwo.ca @TCNLab
BrainsCAN: https://brainscan.uwo.ca/ @Brains_CAN
Touchscreens: https://touchscreencognition.org/ @TouchScreenCog