Category: Trainee opportunities

CIHR funded project- hiring post-doc immediately to study effects of glial senescence on neurons. Successful candidate will have experience and expertise in glio-neuronal co-culture techniques, molecular techniques including RNA/DNA extraction, proteomics, and background/interest in neuroscience/ neurodegenerative disease. Project will include experimental mouse model of mTBI, in vitro studies and access to a Human brain bank with history of brain trauma.

Please contact directly Principal investigator: Lili-Naz.hazrati@sickkids.ca

NIH Funded post-doctoral position to study neuropathological changes of brain trauma in athletes. Candidate should have good knowledge of neuropathological work-up of neurodegenerative diseases in human brains. Project plans to explore and report on all neuropathological changes in a brain bank.
Contact information lili-naz.hazrati@sickkids.ca

Description of the position:

Our research focuses on delineating molecular mechanisms that regulate neural stem cell reprogramming and differentiation, with the ultimate goal of the development of stem cell- based therapy to promote neural repair in the context of various neurological disorders. The individual filling this position is particularly involved in the ongoing project in the lab that is to develop integration-free methodology to reprogram non-neuronal cells into neural cells and to optimize stem cell-based therapies for post-stroke neurovascular regeneration and functional recovery. A variety of molecular, cellular, and behavioral techniques are used in the laboratory, including transgenic mouse models, neurosphere culture, rodent and human reprogramming cell culture and stereotaxic surgery, various neurological degeneration disease models, etc.

Eligibility Requirements:

• Experience in rat stroke models, stereotaxic surgery, Cell Biology (cell line or primary cell culture, immunohistochemistry and immunocytochemistry) and in vivo animal study.
• Excellence in research with strong publication records
• Excellent written and oral communication skills
• Self-motivated and strong desire to learn
• Experience with Human primary cell culture is an asset

Deadline: Until the position is filled.

Individuals who are interested in the position should submit curriculum vitae, a copy of official transcripts, statement of research interest and names of three references to:

jiwang@ohri.ca
Dr. Jing Wang, Ph.D.
Senior Scientist, Sprott Centre for Stem Cell Research
Ottawa Hospital Research Institute
Assistant Professor Department of Cellular & Molecular Medicine

University of Ottawa
Ottawa Hospital, 501 Smyth Rd, Box 511
Ottawa, ON K1H 8L6 CANADA

The Lefebvre lab at uOttawa is recruiting two postdoctoral fellows for the Winter 2020. Candidates interested in computational neuroscience, brain imaging and applied mathematics are encouraged to apply.

Selected candidates will be involved in the following projects:

1. In collaboration with the Griffiths Lab at the CAMH Krembil Center for Neuroinformatics (KCNI) and University of Toronto, the goal of the project is to develop, analyse and explore computational models of non-invasive brain stimulation (e.g. TMS, TES) and their impact on multi-scale neural activity. Specifically, we seek to better understand network-based mechanisms of neural control, oscillatory entrainment and/or stimulation-induced brain plasticity. This project involves a combination of computational and mathematical modelling, has strong potential for knowledge translation, and aims to help inspire new non-invasive treatments for Major Depressive Disorder (MDD).
2. In collaboration with the Hospital for Sick Children (SickKids) in Toronto, the goal of this project is to better understand mechanisms of white matter plasticity, neuron-glia interactions, myelination and its impact on brain function. Using a combination of modelling and simulations, interfacing rodent and human data, the role of the fellow will be to examine the influence of white matter plasticity on neural synchrony and memory. This project involves a combination of computational and mathematical modelling, and strong interactions with experimentalists.

The research will take place in the Department of Biology, the Brain and Mind Institute and the Center for Neural Dynamics of the University of Ottawa, a vivid interdisciplinary research cluster set in the bilingual capital of Canada. Both projects are deployed in the Ottawa-Toronto axis, through close collaborations between uOttawa, uToronto, CAMH KCNI, The University Health Network and The Krembil Research Institute. Based on the research needs and resources, candidates will be required to travel between both cities often. Throughout, candidates will interact closely with clinicians, experimentalists and scholars in neuroimaging.

Requisites:

Candidates should have completed their PhD in physics, mathematics, neuroscience or related disciplines, and have an excellent publication track record. Expertise in programming is a necessity, as well as independence in research. Experience in brain imaging, signal processing and dynamical systems are considered strong assets. Contracts are for one year, with possibility of extension subject to sufficient progress. of one additional year. While the positions are fully funded, candidates are nonetheless expected to apply for external/competitive funding throughout their training.

To apply, please send 1) a letter of interest, 2) a full CV and 3) two(2) letters of reference to jeremie.lefebvre at hotmail dot com. Selected candidates will be contacted for an interview! Job open until filled!

Neurophysiological and structural imaging in PTSD and mild traumatic brain injury

Two postdoctoral research fellow positions at the Hospital for Sick Children (SickKids) are available with immediate start. The positions are initially available for a 1-year period with the possibility of extension.

This project examines functional (MEG, fMRI) and structural (MRI, DTI) brain circuits in posttraumatic stress disorder and mild traumatic brain injury (concussion) in adults. Currently, there are no known imaging markers for psychiatric disease or ‘mild’ brain injuries. This project aims to define signatures for use in a machine learning framework to classify individual cases and identify future targets for neurostimulation in treatment-resistant cases of PTSD and those with lingering symptoms of a concussion.

This is part of an ongoing project that is funded by the Canadian Department of National Defence and Innovation for Defence, Excellence and Security (IDEaS) Program.

A substantial amount of data already exists for this project and the motivated researcher will be able to jump straight into analysis.

 

Your profile

We are seeking two enthusiastic postdoc researchers to work in close collaboration with engineers and research associates in analysing pre-existing and new MEG, MRI & DTI data. Ideally, one researcher will focus on MRI and DTI data, and the other one MEG data, the latter collected during resting state and a task of memory function. Given the initial short-time frame of this position, imaging experience is necessary.

As a postdoc in this position you will be expected to:

• hold a PhD in a relevant area (cognitive neuroscience, neuroimaging, engineering, computer sciences);
• have experience with EEG/MEG and/or MRI/DTI analyses;
• have a knowledge of neuropsychiatric disease that would be advantageous;
• hold a track record in research commensurate with your level of experience post-PhD;
• have experience with computer programming (Matlab, Python, or R) and/or signal processing/time series analyses;
• have excellent communication skills (oral and written);
• be able to work independently and meet deadlines.

 

Your work environment

The principal investigator on this project is Dr. Ben Dunkley.

The candidate will be based in the Neurosciences & Mental Health Program, the Hospital for Sick Children Research Institute. You will work closely with affiliated staff and students who form a group that use neuroimaging to study a variety of brain disorders.

We offer

Salary Scale: $CAD 55,000 to 65,000 gross annual (depending on qualifications and experience).

In addition, we offer an attractive benefits package, that includes partial coverage for dental, drug and medical.

The temporary employment will be for a period of 1 year initially, with a possibility of extension.

Toronto is a world-class rated in the top ten cities worldwide for livability that has a large and rich neuroscience community.

The institute offers many opportunities for career development and additional training as part of the Research Training Centre.

 

Additional information

The post is available from 1st January 2020.

Contact Dr. Ben Dunkley via ben.dunkley@sickkids.ca for more information.

If you wish to apply directly, please send a CV, a cover letter with research statement/interests, and the names of two references.

A funded postdoctoral fellow position is available (start date is negotiable) at Dr. Junchul Kim lab in Psychology/Cell and Systems Biology Department in the University of Toronto, Canada. The lab uses optogenetics, chemogenetics, intersectional viral tools, and calcium imaging to understand neural circuits underlying memory in mice. The selected candidate will also participate in collaborative projects for investigating working memory, anxiety, and escape behaviours. A strong understanding of behavioral neuroscience is desired.

Specific skills and qualifications for the position include:

• PhD in Neuroscience, Physiology, Psychology, or a related field.
• Experience with stereotaxic surgery.
• Experience with mouse behavioral tests.
• Experience with in vivo calcium imaging is desirable.
• Experience with molecular biology is encouraged but not a requirement.

Salaries will be in line with University of Toronto postdoctoral stipend levels. To apply, please send curriculum vitae, a brief statement of research experience and interests, and letters of reference to Dr. Junchul Kim (kim@psych.utoronto.ca). Please also visit our website to learn more about the lab: www.junchulkimlab.com

Contact information

Junchul Kim
100 St.George st, Room 4028.
Department of Psychology, University of Toronto,
Canada,
M5S3G3

Phone 1-416-578-8319

Email: kim@psych.utoronto.ca

Website

http://www.junchulkimlab.com