Post-doctoral researcher(s) in cellular and molecular neuroscience – University of Victoria

Swayne lab

The Swayne Lab in the Division of Medical Sciences at the University of Victoria is recruiting post-doctoral researchers, or research associates, in cellular and molecular neuroscience.

The research projects investigate cross-cellular mechanisms regulating dendritic spine stability. Experiments will involve transgenic models both in situ and in vitro, a variety of imaging techniques (confocal, super-resolution, two-photon microscopy), cell biological and biochemical tools as well as electrophysiology, and behavioural studies. Successful applicants will have the opportunity to apply and expand their expertise in neuron and astrocyte biology across these approaches in a dynamic and collaborative research environment that values integrity, teamwork, equity, diversity, and inclusion.

We encourage researchers who have obtained or will soon obtain their PhD with a demonstrated track record in cellular signaling and imaging research to apply. Previous experience with fluorescence imaging, transgenic models, and primary cell culture is especially valued.

Interested applicants are invited to send their CV, list of references, and brief statement of research interests to Dr. Leigh Anne Swayne: lswayne@uvic.ca.

Posting end date: 2023/10/15

Neuroscience Postdoctoral Scholar positions – University of Calgary

Duration: Minimum 2 years

Start date: Jan 2024 (negotiable)

Salary: TBD, plus medical benefits

 

The projects:

The Kurrasch Lab currently has three open postdoctoral positions (fully funded):

Project 1: Maternal microbiome and mechanistic impacts on the developing brain. This goal of this project is to define the mechanistic events that link adverse changes in the maternal gut to neurodevelopmental disorders in the offspring, using mice as a model system.

Project 2: Embryonic neural sex differentiation. The goal of this project is to determine the programs driving sex dimorphic development of the hypothalamus in mice.

Project 3: Comparative study of adult hypothalamic plasticity. The goal of this project is to determine the role of immature neurons in the adult hypothalamic parenchyma across small and large-brained species.

All projects employ a variety of cutting-edge techniques: single cell ‘omics, advanced microscopy (including iDISCO), in utero electroporation, live cell imaging, behavioral monitoring, human brain organoids (where relevant). Responsibilities include generating, analyzing, graphing, and presenting results, as well as writing and submitting manuscripts. The postdoctoral fellow will be expected to generate new ideas in collaboration with the Principal Investigator. Daily the scholar will interact with other laboratory personnel, including helping to train graduate and undergraduates.

The postdoctoral fellow will join Dr Deborah Kurrasch’s laboratory in the Hotchkiss Brain Institute and Alberta Children’s Hospital Research Institute in the Cumming School of Medicine at the University of Calgary. Each position is fully funded.

Interested applicants please provide:

  • a cover letter with statement of research experience and interests,
  • curriculum vitae,
  • the names and contact information for three persons who have agreed to provide references.

Deadline for application is October 31, 2023.

Submit applications via email directly to Deborah Kurrasch, kurrasch@ucalgary.ca.

Please indicate PDF application in the subject line.

Download this advertisement (PDF file)

 

Post-Doctoral Researcher Positions (Clinical research) – Neuropsychiatry Team Research Program at the University of Western Ontario

Post-Doctoral Researcher Positions are available to work on a newly funded Neuropsychiatry Team Research Program at the University of Western Ontario. Our program will be investigating the effects of adolescent exposure to nicotine on increased risk for developing mood and anxiety disorders in later life (see Addiction Biology, 26(2):e12891; Cerebral Cortex, 29:3140-3153; Neuropsychopharmacology, 39:2799-815, Drug Alcohol Depend, 215:108215). Experiments will comprise an integrative combination of functional brain imaging with fMRI, connectomics using diffusion tensor imaging, magnetic resonance spectroscopy measuring neurotransmitter levels in various neural targets of interest, including the prefrontal cortex and ventral striatum. Studies will also use genomic approaches to examine and identify genetic biomarkers for nicotine-related and mood/anxiety disorder risks. Research will be conducted in patient populations with histories of adolescent nicotine exposure and mood/anxiety disorders selected from local clinics.

Selected applicants will have the opportunity to learn multiple neuroscience and neuropsychiatry-based research techniques while working in a team of leading experts in the fields of neuroimaging, neurodevelopment, behavioural neuroscience, genomics and mood/anxiety disorders.

We encourage applications from candidates with expertise in clinical neuropsychiatry, preferably with backgrounds in neuroimaging and/or genomic analyses.

Interested applicants should send expressions of interest and a current C.V. to: AddictionResearchGroup@protonmail.com

 

Post-Doctoral Researcher Positions (pre-clinical research) – Neuropsychiatry Team Research Program at the University of Western Ontario

Post-Doctoral Researcher Positions are available to work on a newly funded Neuropsychiatry Team Research Program at the University of Western Ontario. Our program will be investigating the effects of adolescent exposure to nicotine on increased risk for developing mood and anxiety disorders in later life (see Addiction Biology, 26(2):e12891; Cerebral Cortex, 29:3140-3153; Neuropsychopharmacology, 39:2799-815, Drug Alcohol Depend, 215:108215). Experiments will comprise an integrative combination of studies using pre-clinical rodent models (nicotine vaping exposure), neuroimaging, behavioural pharmacology, molecular analyses and in vivo neuronal electrophysiology. Pre-clinical studies will be translated into human imaging studies (magnetic resonance spectroscopy, diffusion tensor imaging, fMRI and genomic analyses) in patient populations with histories of adolescent nicotine exposure and mood/anxiety disorders.

Selected applicants will have the opportunity to learn multiple neuroscience and neuropsychiatry-based research techniques while working in a team of leading experts in the fields of neuroimaging, neurodevelopment, behavioural neuroscience, genomics and mood/anxiety disorders. We encourage applications from candidates with expertise in pre-clinical fields of neuroscience, preferably with backgrounds in translational neuropsychiatry research, behavioural pharmacology and neuronal electrophysiology.

Interested applicants should send expressions of interest and a current C.V. to: AddictionResearchGroup@protonmail.com

Postdoctoral Position in Systems Neuroscience at the University of Toronto Scarborough

The Developmental Systems Neuroscience lab (https://devsneurolab.com/) is looking for a highly motivated postdoc to lead a fully funded project intersecting neuronal activity-tagging (engrams), synaptic transmission and behaviour. Our group uses a combination of slice electrophysiology, chemo/optogenetics, fiber photometry and behavior to investigate the neural basis of emotional learning and affective behaviour. Come to our diverse and beautiful campus, and join a supportive, collaborative and mentorship-focused lab!

Contact information Please send a CV, list of references and statement of interests to:
Maithe Arruda-Carvalho
m.arrudacarvalho@utoronto.ca
https://devsneurolab.com

Postdoc positions in visual neuroscience at Université de Montréal

The Neurophotonics lab of the School of Optometry of the University of Montreal is looking for postdocs. Our projects focus on the plasticity of cortical maps and functional connectivity in different models of blindness and stroke affecting visual functions. We are also interested in the spatial coding of information in the context of Brain/Machine interfaces and the development of neuroprosthesis to restore vision.
We use a platform for measuring and manipulating brain functions in mice performing visual cognitive tasks in combination with neurophotonic approaches such as calcium imaging (macroscopic or multi-photon) or optogenetics.
We are also interested in the development of technologies applied to neuroscience, in collaboration with companies.
The support of the lab (CIHR, NSERC) will guarantee a scholarship for trainees who do not yet have the support of funding organizations.

To apply:

  • You must have experience in the field of neurophotonics (such as: calcium imaging, in vivo multiphoton microscopy, optogenetics, etc.)
  • You will also need to have experience in data analysis (with Matlab or Python ideally)
  • Qualifications in the field of rodent behavioral measurements, computational neuroscience or biomedical engineering (3D design/printing, electronics, etc.) could be an important asset

Lab website: https://www.opto.umontreal.ca/cortex/
Contact information Send your CV and cover letter (and any other documents you think could be relevant: transcript, achievement, etc.) to Matthieu Vanni: matthieu.vanni@umontreal.ca

Postdoctoral Researcher – Hazrati lab, McGill University

We are seeking a postdoctoral researcher to advance projects within our lab studying the molecular mechanisms driving brain dysfunction after mild traumatic brain injury (mTBI). In particular, we are interested in discovering novel molecular mechanisms associated with trauma which may reflect clinicopathology and/or serve as potential biomarkers.

This position will involve studies using human brain tissue, mouse models, Stereotaxic animal surgery,  mammalian cell culture, and thus our lab emphasizes the importance of translational science. The successful candidate will develop a novel research project using these materials to further our understanding of mild traumatic brain injury, and will contextualize findings to other projects within the lab and across collaborations.

The postdoctoral researcher in this lab will receive strong mentorship and career support, along with a competitive postdoctoral salary and benefits package. There is opportunity for travel to national and international conferences with a successfully funded project.

Qualifications:

  • PhD in relevant biological sciences field of study (neuroscience preferred)
  • Research expertise and hands-on experience with the following: experimental design, nucleic acid and protein assays, microscopy/imaging techniques, animal studies, mammalian cell culture, single cell sequencing .
  • Expertise and knowledge about cellular senescence, fat metabolism, mitochondrial dysfunction and/or role of BRCA1 in brain will be also an asset
  • Preferred (not required, but an asset) skills: bioinformatic data analysis, R programming language
  • Ability to work both independently with minimal supervision and in a team setting (collaborative in nature)
  • Excellent written and verbal communication skills (must be able to present project ideas and data effectively to experts and non-experts)
  • Track record of publications in peer-reviewed journals
  • Experience with grant writing (including budgets) is an asset

Responsibilities:

  • Initiate new projects in the lab and collect/interpret data for grants (CIHR) and publications
  • Get involved with ongoing lab projects as much as possible, providing scientific expertise and technical assistance where needed
  • Collect data for CIHR and other grants, assist in grant writing including budgets
  • Assist graduate students in the lab with projects
  • Assist with regulatory paperwork such as REBs, AUPs, SOPs, and lab notebooks.

If you are interested, please send your CV and cover letter to lili-naz.hazrati@mcgill.ca with the contact information for two references.

Postdoc in Barcoded Connectomics and Circuit Neuroscience – Johns Hopkins School of Medicine in Baltimore, MD, USA

We are looking for several postdoctoral fellows to join the Kebschull Lab at the Department of Biomedical Engineering at the Johns Hopkins School of Medicine in Baltimore, MD, USA. These NIH-funded positions are for postdocs to develop new tools to integrate barcoded connectivity tracing, gene expression, and function in the zebra finch brain or bring barcoded connectomics to NHPs and tackle questions in circuit evolution.

In the lab, we develop and apply cutting-edge molecular and neuroanatomical tools to study how brain circuits change over the course of an animal’s lifetime in disease and over the course of evolution. We specialize in barcode sequencing-based high-throughput connectomics (e.g. BRICseq, MAPseq) and in situ sequencing. Recent relevant papers include Kebschull et al. 2020 Science, Huang et al. 2020 Cell, Han et al. 2018 Nature, and Kebschull et al. 2016 Neuron.

Candidates must hold a Ph.D. degree (or equivalent) in neuroscience, molecular biology, biomedical engineering or a related field. The ideal candidate should have molecular biology and some bioinformatics skills and be passionate about tool development and the songbird or NHP research. Previous experience in either system is not required. We particularly encourage applications from any underrepresented or minority group.

Our lab is located on the School of Medicine Campus of Johns Hopkins University, surrounded by world-class neuroscience and biomedical engineering labs. We are committed to establishing a first-class, stimulating, diverse, and equitable environment in our new lab to allow you to flourish, achieve your goals, and further your career.

 

Contact information

Qualified applicants should send a letter describing their current and future research interests, their CV, and names and contact details for three references to kebschull@jhu.edu. More information is available on https://www.kebschull-lab.org/.

Postdoctoral Researcher in Translational Rodent to Human Pain Models

About the position:

Position: Postdoctoral researcher for a two year term, with the possibility of extension

Field of Specialization: Spinal cord nociceptive processing; translational pain models

Academic Group: Hildebrand Pain Lab, Department of Neuroscience, Carleton University

Sources of Funds: 2023-2028 CIHR Project Grant, potential future industrial R&D fellowship

Start Date: May 1, 2023 (or earlier/later depending on applicant’s availability)

Closing Date: March 30, 2023

The Hildebrand Pain Lab (HildebrandPainLab.com) at Carleton University (and affiliated with the Ottawa Hospital Research Institute) invites applications for a postdoctoral research position investigating spinal mechanisms of nociceptive processing in rodent and human tissue models. This translational project involves combining cutting-edge high density multi-electrode array (MEA) recordings with the Hildebrand lab’s unique ability to collect highly viable tissue from human organ donors. Using this powerful combination, the applicant will investigate how molecular and cellular mechanisms of spinal excitability and pain processing are conserved and/or diverge across sex and species. Beyond these physiological questions, the applicant will test how targeting specific molecular players with current and potential future therapeutic compounds impacts excitability in spinal nociceptive circuits of both rodents and humans.

The skills, networks, and mentorship gained through this translational pain project will equip the candidate for potential careers in academic, industrial, and/or healthcare-related fields. Along with direct supervision and mentorship by Dr. Hildebrand, the applicant will be working alongside a neurosurgeon/clinical research scientist collaborator at the Ottawa Hospital, Dr. Eve Tsai (https://www.ohri.ca/profile/etsai), with the opportunity to participate in the surgical collection of spinal cord tissue from neurologic determination of death organ donors. Because of the high translational value of these rodent-to-human spinal cord physiology and pharmacology experiments, the applicant will also have the opportunity to work with and be mentored by pharmaceutical researchers that have ongoing collaborative research partnerships with the Hildebrand Pain Lab.

Qualifications:

Candidates must have a Ph.D. in a relevant field, with neuroscience-related research experience including performing electrophysiological, pharmacological, and/or biochemical experiments on ex vivo nervous system tissue. Expertise in analysis of large datasets and coding is also an asset. The position is full time, and salary will be commensurate with experience. The postdoc will be considered unionized, as a member of PSAC Local 77000. Information on this bargaining unit can be found here: https://psac77000.ca/. Optional extended health and dental benefit plans are available with this position.

The Hildebrand Pain Lab and Carleton University are strongly committed to fostering diversity within their communities as a source of excellence, cultural enrichment, and social strength. We welcome those who would contribute to the further diversification of our team, including, but not limited to: women; visible minorities; First Nations, Inuit and Métis peoples; persons with disabilities; and persons of any sexual orientation or gender identity and expressions. We understand that career paths vary. Legitimate career interruptions will in no way prejudice the assessment process and their impact will be taken into careful consideration.

Application instructions:

Completed applications should be sent as one single PDF document to Dr. Hildebrand (mike.hildebrand@carleton.ca) and should include a cover letter highlighting relevant research experiences and how this position fits with your career goals, as well as a curriculum vitae that includes the names and contact information of three referees familiar with your past work and experiences. Please indicate in your application if you are a Canadian citizen or permanent resident of Canada.

About Carleton University:

The Neuroscience department (https://carleton.ca/neuroscience/) is a dynamic and growing academic/research unit at Carleton University that includes a diverse range of research interests, outreach activities, and networking/mentorship opportunities. To learn more about our University and the City of Ottawa, please visit https://carleton.ca/provost/reports/.

Contact information

Michael Hildebrand, mike.hildebrand@carleton.ca
Associate Professor and Graduate Chair, Carleton University
Affiliate Investigator, Ottawa Hospital Research Institute
1125 Colonel By Drive
6310 Health Sciences Building
Ottawa, ON K1S 5B6 CANADA

 

Posting end date

2023/06/01

Download – PDF

 

Post Doctoral Scholar – experimental detection of ultra-weak photon emission from biological systems

Nature of the Work: 

The Faculty of Science has been catalyzing change and inspiring discovery, creativity, and innovation for over 50 years. Our strategic direction integrates current and emerging strengths with areas targeted for future growth and investment. Our strategic priorities, goals, and values guide our mission to advance research, scholarship, and innovation, create authentic learning experiences, and inspire careers of the future. We fuel transformational change, and build a strong community through teaching, learning, research, scholarship, and collaborative partnerships. We do this work to generate curiosity-drive discovery and contribute solutions to society’s grand challenges. For more information, visit science.ucalgary.ca.

We thrive in the dynamic context of the University of Calgary, one of Canada’s most youthful and innovative universities. We are a bold and ambitious research university, grounded in innovative learning and teaching, fully engaged in Calgary’s entrepreneurial spirit.

This is a full-time fixed term appointment, part of the AUPE Bargaining Unit.

Primary Purpose of the Position: 

The postdoctoral researcher is responsible for performing experimental research on detecting ultra-weak photon emission from        biological samples. The candidate will plan, perform and analyze experiments on biological samples using single-photon detection systems. The candidate’s tasks will be based at the National Research Council of Canada in Ottawa with occasional research visits to U. Calgary.  These two sites are home to teams with expertise in biophoton detection/theory and neuroscience applications, who will jointly mentor and supervise the candidate. The candidate is expected to support the development of funding and attracting graduate   students to ensure continued growth in the area of quantum biology. The incumbent will be expected to also present research accomplishments and findings in internal and external meetings, conferences, reports and publications.

Qualifications/Expertise Required: 

  • A PhD in neuroscience, biology or related fields is required
  • Experience in operating optical imaging equipment and image analysis tools and software
  • Experience in preparing and maintaining in vitro biological cell preparations (ideally dissociated cultures and brain slices)
  • An asset would be experience in assessing effect of pharmacological agents on cells and tissues, preferably neuronal in origin
  • An asset would be experience in theoretical and experimental aspects of light emission from biological systems
  • An asset would be knowledge of quantum mechanics.
  • Ability to communicate effectively with internal and external stakeholders
  • Capable of assisting expansion and development of research projects in biophoton research
  • A high level of effective time and project management, personal initiative, communications skills and teamwork
  • Majority of job tasks will be performed on-site at National Research Council (NRC) in Ottawa
  • Position requires flexibility to occasionally visit U. Calgary for research collaboration
  • Ability to travel nationally and internationally
  • Knowledge of university policies and procedures is an asset.

Accountabilities/Tasks and Duties:  

Technical:

The candidate will primarily be responsible for operation of an experimental setup designed to detect single   photons (biophotons) from biological samples. Biological samples to be investigated will include living tadpoles and various neuron culture assemblies. Biophoton emission will be investigated using pharmacological and possibly electrophysiological approaches. The incumbent will also be responsible for the analysis and interpretation of the data, working with the teams at U. Calgary and the NRC. The incumbent will design, implement, and consult with the Principal Investigator on projects and programs. The candidate will be expected to identify and pursue new research opportunities aligned with the overall vision of the lab.

Mentorship/Coaching:

The candidate will provide training of undergraduate and graduate students in experimental and theoretical   research techniques, as well as presentation skills(written and oral).

Publishing/Presenting Research: 

  • Publish/present research accomplishments at both the national and international level, including in high impact/selective academic journals.
  • Prepare manuscripts describing findings for submission for publication, and lead process of responding to referees/editors during the peer review process.

Occupational Health& Safety: 

  • Understands and complies with the requirements of the University’s Occupational Health and Safety Policy
  • Has knowledge of and understands the expectations of the University’s Occupational Health and Safety Management System (OHSMS) and applicable Faculty/Departmental/Unit specific health and safety policies and procedures
  • Ensures that all work conducted is in accordance with the Alberta Occupational Health and Safety Act, Regulation and Code and other health and safety legislation as applicable

Position posting at UCalgary

https://science.careers.ucalgary.ca/jobs/10577986-post-doctoral-scholar-physics-and-astronomy-and-cell-biology-and-anatomy