Delayed brain development may lead to brain injury in newborns with heart birth defects

Dr. Steven Miller
Dr. Steven Miller

Newborns with congenital heart disease are found to be highly vulnerable to brain injuries. While the link between heart defects and slower brain development has long been demonstrated, a new study published on July 16 in Neurology has further uncovered a direct connection between altered brain development and brain injuries in newborns with congenital heart disease. Continue reading

Identifying genes that maintain stem cells and healthy cognition

Dr. David Kaplan
Dr. David Kaplan

The cellular mechanisms that promote long-term cell survival and maintenance of the adult nervous system are only poorly-understood, in spite of their clinical relevance. A study from the Hospital for Sick Children in Toronto and the University of Toronto has identified one such mechanism in brain stem cells that may be important for healthy cognitive aging. Continue reading

McMaster study debunks controversial MS theory

Dr. Ian Rodger
Dr. Ian Rodger

There is no evidence that impaired blood flow or blockage in the veins of the neck or head is involved in multiple sclerosis, says a McMaster University study.

The research, published online by PLOS ONE Wednesday, found no evidence of abnormalities in the internal jugular or vertebral veins or in the deep cerebral veins of any of 100 patients with multiple sclerosis (MS) compared with 100 people who had no history of any neurological condition. Continue reading

A new role for sodium in the brain

Dr. Derek Bowie
Dr. Derek Bowie

Findings identify a novel pharmaco-logical target for drug development

Researchers at McGill University have found that sodium – the main chemical component in table salt – is a unique “on/off” switch for a major neurotransmitter receptor in the brain. This receptor, known as the kainate receptor, is fundamental for normal brain function and is implicated in numerous diseases, such as epilepsy and neuropathic pain. Continue reading