Association between low vitamin D and MS

Brent Richards
Brent Richards

Having low levels of vitamin D doubles the risk of developing multiple sclerosis, an association that researchers conclude supports a causal relationship.
Low levels of vitamin D significantly increase the risk of developing multiple sclerosis (MS), according to a study led by Dr. Brent Richards of the Lady Davis Institute at the Jewish General Hospital, and published in PLOS Medicine. Continue reading

Why we’re smarter than chickens

Benjamin Blencowe
Benjamin Blencowe
Researchers at U of T’s Donnelly Centre uncover protein part that controls neuron development.U of T researchers have discovered that a single molecular event in our cells could hold the key to how we evolved to become the smartest creatures on the planet.

Professor Benjamin Blencowe and his team at the Donnelly Centre for Cellular and Biomolecular Research have determined that a small change in a protein called PTBP1 spurred the creation of neurons and fuelled the evolution of mammalian brains to become the largest and most complex among vertebrates. Continue reading

Scientists identify key gene associated with addiction

Salah El-Mestikawy
Salah El-Mestikawy
A new study published in the journal Molecular Psychiatry by a team led by Salah El Mestikawy, Ph.D., researcher at the Douglas Mental Health University Institute (CIUSSS de l’Ouest-de-l’île-de-Montréal), professor at McGill University and head of research at CNRS INSERM UPMC in Paris, opens the field to new understanding of the molecular mechanism underlying addiction in humans. Continue reading

Researchers discover mechanism involved in chronic pain

Zizhen Zhang
Zizhen Zhang

Chronic pain is one of the most common reasons people visit their doctor, and basic scientists have long been trying to understand it. In Canada, chronic pain costs more than heart disease, HIV and cancer combined. New animal research, published online in Cell Reports on July 23, out of the Cumming School of Medicine has made a discovery that provides more insight into the mechanisms of pain. Continue reading

Practice doesn’t always make perfect (depending on your brain)

Dr. Robert Zatorre
Dr. Robert Zatorre

Study fuels nature versus nurture debate
How do you get to Carnegie Hall? New research on the brain’s capacity to learn suggests there’s more to it than the adage that “practise makes perfect.” A music-training study by scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and colleagues in Germany found evidence to distinguish the parts of the brain that account for individual talent from the parts that are activated through training. Continue reading

This is your brain on fried eggs

Stephanie Fulton
Stephanie Fulton

High-fat feeding can cause impairments in the functioning of the mesolimbic dopamine system, says Stephanie Fulton of the University of Montreal and the CHUM Research Centre (CRCHUM.) This system is a critical brain pathway controlling motivation. Fulton’s findings, published in Neuropsychopharmacology, may have great health implications. Continue reading

His and hers pain circuitry in the spinal cord

Mike Salter
Mike Salter
Jeffrey Mogil
Jeffrey Mogil
New animal research reveals fundamental sex differences in how pain is processed.
New research released today in Nature Neuroscience reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain—which is by far the most prevalent human health condition—and the way we execute basic biomedical research using mice. Continue reading