SickKids study shows how the brain creates the “big picture” by amalgamating memories over time

Paul Frankland
Paul Frankland

Scientists have long hypothesized that our overall understanding of the world is based on collections of experiences, rather than distinct, individual memories. In a new study led by The Hospital for Sick Children (SickKids), neuroscientists demonstrate for the first time that long after a set of related memories is formed the brain amalgamates the memories based on their commonalities, forming a pattern or category. Continue reading

What is being said in the media and academic literature about neurostimulation?

Eric Racine
Eric Racine

Over the past several decades, neurostimulation techniques such as transcranial direct current stimulation (tDCS) have gradually gained favour in the public eye. In a new report, published in the prestigious scientific journal Neuron, IRCM ethics experts directed by University of Montreal’s professor Éric Racine raise important questions about the rising tide of tDCS coverage in the media, while regulatory action is lacking and ethical issues need to be addressed. Continue reading

A tiny molecule may help battle depression

Gustavo Turecki
Gustavo Turecki

Researchers find a small molecule that predicts treatment response for depressed patients

Levels of a small molecule found only in humans and in other primates are lower in the brains of depressed individuals, according to researchers at McGill University and the Douglas Institute. This discovery may hold a key to improving treatment options for those who suffer from depression. Continue reading

‘Sticky synapses’ can impair new memories by holding on to old ones

Bamji and Mills
Bamji and Mills

A team of UBC neuroscientists has found that synapses that are too strong or ‘sticky’ can actually hinder our capacity to learn new things.

University of British Columbia researchers have discovered that so-called “sticky synapses” in the brain can impair new learning by excessively hard-wiring old memories and inhibiting our ability to adapt to our changing environment.

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Unlocking autism’s code: Professor Stephen Scherer

Stephen Scherer
Stephen Scherer

New formula for identifying disorder at younger age could mean earlier therapy, better tests

A Toronto research team has identified the formula for diagnosing autism spectrum disorder (ASD) at an earlier age. This will let patients receive therapies at an earlier age, while helping to create more advanced genetic diagnostic tests.

Published recently in Nature Genetics, the research unravels the autism code by creating a “genetic formula” that will help clinicians identify genetic mutations that have the highest and lowest likelihood of causing ASD. Continue reading

Brenda Milner awarded prestigious Kavli Prize in Neuroscience

Brenda Milner
Brenda Milner

Brenda Milner, an active researcher at the age of 95 at the Montreal Neurological Institute and Hospital (The Neuro) is a recipient of the prestigious Kavli Prize in Neuroscience for 2014.

The Norwegian Academy of Science and Letters also announced Thursday winners in Astrophysics and Nanoscience. Milner shares the Neuroscience award with two other researchers. Continue reading

Timing is everything

Ed Ruthazer
Ed Ruthazer

Scientists control rapid re-wiring of brain circuits using patterned visual stimulation

In a new study, published in this week’s issue of the journal Science, researchers show for the first time how the brain re-wires and fine-tunes its connections differently depending on the relative timing of sensory stimuli. In most neuroscience textbooks today, there is a widely held model that explains how nerve circuits might refine their connectivity based on patterned firing of brain cells, but it has not previously been directly observed in real time. Continue reading

Scientists discover a new way to enhance nerve growth following injury

Doug Zochodne
Doug Zochodne

New research published out of the University of Calgary’s Hotchkiss Brain Institute (HBI) uncovers a mechanism to promote growth in damaged nerve cells as a means to restore connections after injury. Dr. Doug Zochodne and his team have discovered a key molecule that directly regulates nerve cell growth in the damaged nervous system. His study was published in the prestigious journal Nature Communications, with lead authors Drs. Kim Christie and Anand Krishnan. Continue reading

New research may explain loss of early childhood memories

Paul Frankland
Paul Frankland

Why do we tend to forget earlier memories, especially those from childhood, as we get older? New research from The Hospital for Sick Children (SickKids) brings fresh insight into the mystery of infantile amnesia and begins to explain why we have no memories from our earliest years. Researchers demonstrate that new neuron formation, or neurogenesis, in the area of the brain where memories are stored, called the hippocampus, is associated with memory loss. Continue reading