Frédéric Charron, CAN 2012 Young Investigator, publishes in Developmental Cell.
Researchers at the IRCM show that a protein called Sonic Hedgehog causes DNA damage – They discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. Continue reading
According to a study conducted by pediatricians and researchers at Sainte-Justine University Hospital Research Center (Sainte-Justine) and Université de Montréal published online in the prestigious medical journal Nature Medicine on September 14, 2014, Continue reading
Researchers at Western University have extended their game-changing brain scanning techniques by showing that a short Alfred Hitchcock movie can be used to detect consciousness in vegetative state patients. Continue reading
When you reach into your pocket, you can easily tell a button from a coin. Solving this seemingly simple problem is actually amazingly complicated. The long-held scientific explanation is that neurons in the cerebral cortex, which is the part of the brain reserved for the most complicated functions, make the differentiation but recent findings Continue reading
Dopamine plays a key role in decisions involving risk and reward, says UBC’s Stan Floresco.
A gambler’s decision to stay or fold in a game of cards could be influenced by a chemical in the brain, suggests new research from the University of British Columbia. Continue reading
It’s in the brain where we perceive the unpleasant sensations of pain, and researchers have long been examining how calcium channels in the brain and peripheral nervous system contribute to the development of chronic pain conditions. Continue reading
In a new study published 2 September 2014 in the scientific journal Neuron, Sam David and his team at the Research Institute of the McGill University Heath Centre shed light on why inflammation after nervous system injury, such as spinal cord trauma, worsens damage and functional loss. Sam David says that “a cytokine called tumor necrosis factor (TNF) and iron from red blood cells that are phagocytosed by macrophages favours a prolonged shift to harmful pro-inflammatory type of macrophage that is detrimental to recovery.” Continue reading
Research by Dr. Sylvain Williams shows that the flow of activity in the hippocampus, a brain region essential for memory, is actually bidirectional, rather than just unidirectional
A study just published in the prestigious Nature Neuroscience journal by Sylvain Williams, PhD, and his team, of the Research Centre of the Douglas Mental Health University Institute and McGill University, opens the door towards better understanding of the neural circuitry and dynamic mechanisms controlling memory as well of the role of an essential element of the hippocampus – a sub-region named the subiculum. Continue reading
New research led by University of Toronto neurologist Andrew Lim sheds light on sleep disruption in aging adults.
“In many older people with insomnia and other patterns of sleep disruption, the underlying cause is unknown,” said Lim, assistant professor of neurology and neuroscientist at Sunnybrook Health Sciences.
“We provide evidence that loss of neurons in a particular region of the brain that controls sleep may be an important contributor to insomnia in many older individuals.” Continue reading
Study suggests ways to treat these deficits before the psychiatric symptoms develop
Researchers at the University of Montreal and CHU Sainte-Justine Research Centre have traced the origins of ADHD, substance abuse and conduct disorder, and found that they develop from the same neurocognitive deficits, which in turn explains why they often occur together. “Psychopathology exists on multiple continua of brain function. Some of these dimensions contribute to a multitude of problems, others contribute to specific problems. Together, they explain patterns of comorbidity such as why ADHD and conduct problems co-occur with substance misuse at such a high rate,” explained the study’s lead author, Professor Patricia Conrod. Continue reading
