PhD student Matthew Durk and Professor K. Sandy Pang at the University of Toronto’s Leslie Dan Faculty of Pharmacy were lead and senior authors on a study recently published as a featured article in the Journal of Neuroscience (Vol 34:7091-7101, 2014).
This study explores the role the Vitamin D receptor may play in the prevention and treatment of Alzheimer’s disease. Continue reading
A recent study published in the journal Annals of Neurology reports that healthy tissue grafted to the brain of people with Huntington’s disease, in the hope of countering this neurological disorde, also develop signs of disease several years after transplantation. This discovery has not only profound implications for our understanding of the disease and how to treat it, but could also lead to the development of new therapies against various neurodegenerative disorders. Continue reading
Scientists have long hypothesized that our overall understanding of the world is based on collections of experiences, rather than distinct, individual memories. In a new study led by The Hospital for Sick Children (SickKids), neuroscientists demonstrate for the first time that long after a set of related memories is formed the brain amalgamates the memories based on their commonalities, forming a pattern or category. Continue reading
Over the past several decades, neurostimulation techniques such as transcranial direct current stimulation (tDCS) have gradually gained favour in the public eye. In a new report, published in the prestigious scientific journal Neuron, IRCM ethics experts directed by University of Montreal’s professor Éric Racine raise important questions about the rising tide of tDCS coverage in the media, while regulatory action is lacking and ethical issues need to be addressed. Continue reading
Researchers find a small molecule that predicts treatment response for depressed patients
Levels of a small molecule found only in humans and in other primates are lower in the brains of depressed individuals, according to researchers at McGill University and the Douglas Institute. This discovery may hold a key to improving treatment options for those who suffer from depression. Continue reading
Discovery may lead to relief for victims of a range of neurological disorders
University of Toronto biologists leading an investigation into the cells that regulate proper brain function, have identified and located the key players whose actions contribute to afflictions such as epilepsy and schizophrenia. Continue reading
A team of UBC neuroscientists has found that synapses that are too strong or ‘sticky’ can actually hinder our capacity to learn new things.
University of British Columbia researchers have discovered that so-called “sticky synapses” in the brain can impair new learning by excessively hard-wiring old memories and inhibiting our ability to adapt to our changing environment.
New formula for identifying disorder at younger age could mean earlier therapy, better tests
A Toronto research team has identified the formula for diagnosing autism spectrum disorder (ASD) at an earlier age. This will let patients receive therapies at an earlier age, while helping to create more advanced genetic diagnostic tests.
Published recently in Nature Genetics, the research unravels the autism code by creating a “genetic formula” that will help clinicians identify genetic mutations that have the highest and lowest likelihood of causing ASD. Continue reading
Brenda Milner, an active researcher at the age of 95 at the Montreal Neurological Institute and Hospital (The Neuro) is a recipient of the prestigious Kavli Prize in Neuroscience for 2014.
The Norwegian Academy of Science and Letters also announced Thursday winners in Astrophysics and Nanoscience. Milner shares the Neuroscience award with two other researchers. Continue reading
Scientists control rapid re-wiring of brain circuits using patterned visual stimulation
In a new study, published in this week’s issue of the journal Science, researchers show for the first time how the brain re-wires and fine-tunes its connections differently depending on the relative timing of sensory stimuli. In most neuroscience textbooks today, there is a widely held model that explains how nerve circuits might refine their connectivity based on patterned firing of brain cells, but it has not previously been directly observed in real time. Continue reading
