“Big Data” study discovers earliest sign of Alzheimer’s

Alan Evans
Alan Evans
Research underlines importance of computational power in future neurological breakthrough.
Scientists at the Montreal Neurological Institute and Hospital have used a powerful tool to better understand the progression of late-onset Alzheimer’s disease (LOAD), identifying its first physiological signs.
Led by Dr. Alan Evans, a professor of neurology, neurosurgery and biomedical engineering at the Neuro, the researchers analyzed more than 7,700 brain images from 1,171 people in various stages of Alzheimer’s progression using a variety of techniques including magnetic resonance imaging (MRI) and positron emission tomography (PET). Blood and cerebrospinal fluid were also analyzed, as well as the subjects’ level of cognition. Continue reading

Hummingbird vision wired to avoid high-speed collisions

Douglas Altshuler
Douglas Altshuler
Hummingbirds are among nature’s most agile fliers. They can travel faster than 50 kilometres per hour and stop on a dime to navigate through dense vegetation.

Now researchers have discovered that the tiny birds process visual information differently from other animals, perhaps to handle the demands of their extreme aerial acrobatics.

“Birds fly faster than insects and it’s more dangerous if they collide with things,” said Roslyn Dakin, a postdoctoral fellow in the UBC’s department of zoology who led the study. “We wanted to know how they avoid collisions and we found that hummingbirds use their environment differently than insects to steer a precise course.” Continue reading

Sick Kids Researchers May Have Finally Figured Out Why We Can Remember Multiple Memories at Once

Have you ever noticed when you remember something from your past, you may also recall other moments from that time. It seems to be even more pronounced when remembering a moving event, such as the assassination of President John F. Kennedy, the demise of the space shuttle Challenger, and more recently, the tragic events of 9/11.
While many of us experience these multiple memories, the mechanism behind their formation has been a biological enigma. For over a century researchers have tried to figure out how these combinations – or co-allocations – of memories occur. Yet successes have been few and far between. Continue reading

Understanding how chemical changes in the brain affect Alzheimer’s disease

Marco Prado
Marco Prado

A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life. The findings show that long-term suppression of the neurotransmitter acetylcholine – a target for anticholinergic drugs – results in dementia-like changes in the brain.

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Parkinson’s disease may be a key to solving the glioblastoma puzzle: SickKids-led study

Peter Dirks
Peter Dirks

As the most common and aggressive cancerous brain tumour in adults, a glioblastoma diagnosis remains a death sentence due to its  resistance to all currently-available treatments. Research in this area has been slow and steady to date. Now, with promising new findings, a Canadian team of scientists is ushering brain cancer research into a new realm: the field of neurodegenerative medicine and neurochemical signalling. Continue reading

Want To Retain Memories? McGill Researchers Suggest More REM Sleep May Do The Trick

Improving memory is a quest that never seems to end. For centuries, humans have attempted to find the right combination of social actions to better retain what we’ve learned. Over the years, some options have shown promise such as fasting  and strenuous exercise. While effective, they are not particularly popular. Then there’s the odd concept of intranasal injection of insulin. It goes to show that an idea with promise might not be the best idea. Continue reading

McGill Researchers Have Found A Critical Component To Learning A Language

Acquiring a language is a difficult process. One of the best ways to learn involves the use of a tutor. This one-on-one interaction allows for direct learning as well as interaction without distraction. Usually, the teacher is an expert in that specific language. But when it comes to learning a first language, the most useful tutor happens to be an infant’s parent. Continue reading

SickKids scientists show how memories are linked in the brain

Dr. Sheena Josselyn
Dr. Sheena Josselyn

Some memories just seem to go together. Think about an important experience in your life. You may also closely remember another experience that happened around that time too, like exchanging vows at your wedding, and then your friend’s epic dance moves later that same night. Somehow these two memories seem to be linked in your mind.

A new study led by The Hospital for Sick Children (SickKids), looks at this connection between memories and illustrates how certain memories become linked in the brain. The study is published in the July 22 online edition of Science. Continue reading

University of Victoria Researchers Find A “Starburst” In The Space-Time Continuum of Motion Sensing

Most people take motion sensing for granted. Our eyes pick up on something moving and our brains are sent a signal to let us know something has occurred in our space-time continuum. Despite the simplicity of the task, the mechanisms allowing us this ability are incredibly complex. They have been studied for over fifty years and the neural circuitry underlying motion detection is probably the best described circuitry in the brain. Yet, researchers have not discovered all the answers. Continue reading