Researchers from Université Laval affiliated CHUQ discover a new therapeutic target for Lou Gehrig’s disease

Jean-Pierre Julien

November 14, 2011. – A research team from Université Laval, led by Jean-Pierre Julien, has taken a new step in understanding the cellular mechanisms involved in Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis (ALS). This disease is characterized by degeneration of neurons that control muscle activity. Continue reading

Scientists Highlight Link Between Stress and Appetite

Pittman and Bains

Researchers in the Hotchkiss Brain Institute (HBI) at the University of Calgary’s Faculty of Medicine have uncovered a mechanism by which stress increases food drive in rats. This exciting discovery, published in the journal Neuron, could provide important insight into why stress is thought to be one of the underlying contributors to obesity.

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Potential harm, but no demonstrated benefit from depression screening in primary care

Brett Thombs

September 19, 2011 – The Canadian Task Force on Preventive Health Care recommends routine screening for depression during primary care visits when systems are available for coordination of assessment and treatment. An article by an international panel of experts, published in the October issue of the Canadian Medical Association Journal, argues that there is no evidence that screening benefits patients and that, moreover, implementation of the practice would further burden an already financially-strapped health care system. Continue reading

Study exposes major flaws in research on depression screening questionnaires – Research on detection of depression “forecasting yesterday’s weather,” say investigators

Par Hendrike 11:08, 3 May 2006 (UTC) (Travail personnel) [GFDL (www.gnu.org/copyleft/fdl.html) ou CC-BY-SA-3.0 (www.creativecommons.org/licenses/by-sa/3.0/)], via Wikimedia CommonsAugust 16, 2011 – A new analysis, published in the British Medical Journal (BMJ), reports that flawed research studies have exaggerated the degree to which depression screening questionnaires are able to accurately detect people with untreated depression. The number of untreated patients who would actually be detected using these questionnaires may be less than half the number predicted by existing studies. Continue reading

Children of depressed mothers have a different brain – MRI scans show their children have an enlarged amygdala

Amygdalae - there are two in your brain

August 15, 2011 – Researchers think that brains are sensitive to the quality of child care, according to a study that was directed by Dr. Sonia Lupien and her colleagues from the University of Montreal published today in the Proceedings of the National Academy of Sciences. Continue reading

No room for inaccuracy in the brain

The map of your brain is dynamic
July 20, 2011 – Dr. Ed Ruthazer is a mapmaker but, his landscape is the developing brain – specifically the neuronal circuitry, which is the network of connections between nerve cells. His research at The Montreal Neurological Institute and Hospital – The Neuro at McGill University, reveals the brain as a dynamic landscape where connections between nerves are plastic, changing and adapting to the demands of the environment. Continue reading

Montreal researchers awarded for pioneering research into music and brain plasticity

Music affects brain plasticity

July 20, 2011 – The 22nd annual Neuronal Plasticity Prize of the Fondation Ipsen has been awarded to Robert J. Zatorre (Montreal Neurological Institute, BRAMS Laboratory), Isabelle Peretz (University of Montreal, BRAMS Laboratory)  and Helen J. Neville (University of Oregon, Eugene, USA), for their pioneering research in the domain of “Music and Brain Plasticity”. Continue reading

RCM researchers uncover a new piece of the puzzle in the development of our nervous system

Ephrins help guide neuron growth in limbs

July 14, 2011 – Researchers at the Institut de recherches cliniques de Montréal (IRCM) are among the many scientists around the world trying to unearth our nervous system’s countless mysteries. A new piece of the puzzle was recently uncovered by Dr. Artur Kania, Director of the IRCM’s Neural Circuit Development research unit and Associate Professor at Université de Montréal’s Department of Medicine, and a postdoctoral fellow in his laboratory, Dr. Tzu-Jen Kao.

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New genetic clues for schizophrenia De novo mutations are more frequent

DNA sequence
Reading of a DNA sequence

July 11, 2011 – De novo mutations – genetic errors that are present in patients but not in their parents – are more frequent in schizophrenic patients than in normal individuals, according to an international group of scientists led by Dr. Guy A. Rouleau of the University of Montreal and CHU Sainte-Justine Hospital. Continue reading