Why some pain drugs become less effective over time

April 5, 2012 – Researchers at the University of Montreal’s Sainte-Justine Hospital have identified how neural cells are able to build up resistance to opioid pain drugs within hours. “A better understanding of these mechanisms will enable us to design drugs that avoid body resistance to these drugs and produce longer therapeutic responses, including longer-acting opioid analgesics”, lead author Dr. Graciela Pineyro said.

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McGill researchers crack degeneration process that leads to Alzheimer’s

Claudio Cuello
Dr. Claudio Cuello

March 8, 2012 – New study points to possible new therapeutic approaches in treatment of AD. A research group led by Dr. A. Claudio Cuello of McGill University’s Faculty of Medicine, Dept. of Pharmacology and Therapeutics, has uncovered a critical process in understanding the degeneration of brain cells sensitive to Alzheimer’s disease (AD). The study, published in the February issue of the Journal of Neuroscience, suggests that this discovery could help develop alternative AD therapies.

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Open your eyes and smell the roses

Christopher Pack

February 29 2012 – Activating the visual cortex improves our sense of smell. A new study reveals for the first time that activating the brain’s visual cortex with a small amount of electrical stimulation actually improves our sense of smell. The finding published in the Journal of Neuroscience by researchers at the Montreal Neurological Institute and Hospital – The Neuro, McGill University and the Monell Chemical Senses Center, Philadelphia, revises our understanding of the complex biology of the senses in the brain.

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Doctors find new way to predict recurrent stroke

Dr. Coutts (right) and patient

Feb 24, 2012 – New research from the University of Calgary’s Hotchkiss Brain Institute (HBI) shows that using a CT (computerised tomography) scan, doctors can predict if patients who have had a transient ischemic attack (TIA) or minor stroke, with neurological symptoms such as weakness or speech issues, are at risk for another more severe stroke. Continue reading