McGill researchers discover the cause of an inherited form of epilepsy

Dr. Gary Brouhard

Findings could open avenues for improved therapies for a range of conditions

Researchers at McGill University have discovered the cause of an inherited form of epilepsy. The disease, known as double-cortex syndrome, primarily affects females and arises from mutations on a gene located on the X chromosome. Continue reading

Multiple sclerosis patients have lower risk of cancer: UBC-VCH research

Dr. Ellen Kingwell

Multiple sclerosis (MS) patients appear to have a lower cancer risk, according to a new study led by researchers at the University of British Columbia and Vancouver Coastal Health.

The study, published online in the journal Brain, is the first to investigate overall cancer risk in MS patients in North America. Continue reading

The Mammalian Methylome: Investigating how cells regulate gene expression in the brain

Dr. Cathy Barr

In developing humans and other mammals, not all genes are created equal – or equally used. The expression of certain genes, known as imprinted genes, is determined by just one copy of the parents’ genetic contribution. In humans, there are at least 80 known imprinted genes. If a copy of an imprinted gene fails to function correctly – or if both copies are expressed – the result can be a variety of heritable conditions, such as Prader-Willi and Angelman syndromes, or increased risk for cancer. Continue reading

Scientists start explaining Fat Bastard’s vicious cycle

Stephanie Fulton
Stephanie Fulton

May 24, 2012 -Fat Bastard’s revelation “I eat because I’m depressed and I’m depressed because I eat” in the Austin Powers film series may be explained by sophisticated neuroscience research being undertaken by scientists affiliated with the University of Montreal Hospital Research Centre (CRCHUM) and the university’s Faculty of Medicine. Continue reading

Discovery of a gene that causes Joubert Syndrome in the population of the Lower St. Lawrence region of Quebec

Jacques Michaud
May 10, 2012 – C5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. This is what a study in the April issue of The American Journal of Human Genetics reveals. The study was conducted by researchers from the Sainte-Justine University Hospital Research Center and the Centre of Excellence in Neuromics of Université de Montréal’s (CENUM). Continue reading

Neuro researchers sharpen our understanding of memories

Jean-Claude Lacaille
May 2, 2012 – Scientists now have a better understanding of how precise memories are formed thanks to research led by Prof. Jean-Claude Lacaille of the University of Montreal’s Department of Physiology. “In terms of human applications, these findings could help us to better understand memory impairments in neurodegenerative disorders like Alzheimer’s disease,” Lacaille said. The study looks at the cells in our brains, or neurons, and how they work together as a group to form memories. Continue reading

Analytic thinking can decrease religious belief: UBC study

Ara Norenzayan
April 26, 2012 – A new University of British Columbia study finds that analytic thinking can decrease religious belief, even in devout believers.

The study, which will appear in tomorrow’s issue of Science, finds that thinking analytically increases disbelief among believers and skeptics alike, shedding important new light on the psychology of religious belief. Continue reading

Taking it all in: revealing how we sense things

Maurice Chacron

April 24, 2012 – McGill physiology research team sheds light on how the brain processes what we sense

We rely on our senses in all aspects of our lives. Unfortunately, many people suffer from some kind of impaired sensory function. In Canada alone, 600,000 people are visually impaired while almost three million suffer from partial or total hearing loss. Continue reading

Preventing dementia: new research by VCH and UBC shows the trajectory of cognitive decline can be altered in seniors at risk for dementia

Theresa Liu-Ambrose

April 23, 2012 – Cognitive decline is a pressing global health care issue. Worldwide, one case of dementia is detected every seven seconds. Mild cognitive impairment is a well recognized risk factor for dementia, and represents a critical window of opportunity for intervening and altering the trajectory of cognitive decline in seniors. Continue reading