McGill Researchers Have Found A Fungal Toxin May One Day Repair Damage To The Central Nervous System

Injuries are a part of life. In most cases, such as cuts, bruises, tears, and even broken bones, our bodies heal. But when damage occurs to the central nervous system – or as most people call it, CNS – the outlook can be heartbreaking. The cells in this area, known as neurons, simply are not good at regeneration. This is why damage to the spinal cord and retina is considered a dire ailment.

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Two CAN Young Investigator Awards in 2017: Przemyslaw (Mike) Sapieha, from Université de Montréal, and Tuan Trang, from University of Calgary.

The Canadian Association for Neuroscience is proud to announce it will be awarding two Young Investigator Awards in 2017.  The laureates are Przemyslaw (Mike) Sapieha, from Université de Montréal, and Tuan Trang, from University of Calgary.  The CAN nominations committee was equally impressed with both candidates, who have made important contributions to our understanding of the brain and the nervous system in the early stages of their careers.  Both winners have developed a strong program of basic, curiosity-driven research that have led to discoveries that can be used to improve the lives of Canadians. Continue reading

Molecule shown to repair damaged axons

Alyson Fournier

Discovery could be key to treating brain and spinal cord injury

A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.

Andrew Kaplan, a PhD candidate at the Montreal Neurological Institute and Hospital of McGill University, was looking for a pharmacological approach to axon regeneration, with a focus on 14-3-3, a family of proteins with neuroprotective functions that have been under investigation in the laboratory of Dr. Alyson Fournier, professor of neurology and neurosurgery and senior author on the study. Continue reading

Second study from UBC shows “liberation therapy” fails to treat multiple sclerosis

Anthony Traboulsee
Anthony Traboulsee

Opening up narrowed veins from the brain and spinal cord is not effective in treating multiple sclerosis (MS), according to a study led by the University of British Columbia and Vancouver Coastal Health.

The conclusions about so-called “liberation therapy,” which thousands of people with MS have undergone since 2009, represent the most definitive debunking of the claim that MS patients could achieve dramatic improvements from a one-time medical procedure. Continue reading

Largest international study of its kind finds new schizophrenia risk genes

Stephen Scherer
Stephen Scherer

Results of the International Psychiatric Genomics Consortium unveiled

TORONTO – Canadian and international scientists have uncovered six new schizophrenia risk genes in the largest study of its kind. The results of the international Psychiatric Genomics Consortium CNV working group are published in the Nov. 21 advance online edition of Nature Genetics, and further support the important role genes play in susceptibility to schizophrenia, and may be helpful in early diagnosis.

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University of British Columbia Researchers Have Found A Way To Block The High of Cocaine

“If you got that lose, you want to kick them blues, cocaine
When your day is done, and you want to ride on cocaine
She don’t lie, she don’t lie, she don’t lie
Cocaine.”

-Eric Clapton

Despite its illegal status, cocaine remains one of the staples of social drug use. The stimulating effect of the chemical has been glamorized in modern-day culture and continues to be lauded as a means to artificially keep the mind active. Yet, as anyone who has tried this high can tell, the side effects are far less delightful. They include memory loss, increase heart rate, insomnia, and almost instantaneous addiction. Continue reading

UBC scientists create a mouse that resists cocaine’s lure

Shernaz BamjiScientists at the University of British Columbia have genetically engineered a mouse that does not become addicted to cocaine, adding to the evidence that habitual drug use is more a matter of genetics and biochemistry than just poor judgment.

The mice they created had higher levels of a protein called cadherin, which helps bind cells together. In the brain, cadherin helps strengthen synapses between neurons – the gaps that electrical impulses must traverse to bring about any action or function controlled by the brain, whether it’s breathing, walking, learning a new task or recalling a memory.
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