Defective cell ‘battery’ plays central role in neurodegenerative disease

Peter McPherson
Peter McPherson

Jan. 17, 2012 – A devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk has been traced to defects in mitochondria, the ‘batteries’ or energy-producing power plants of cells. This finding by a team of researchers, led by investigators from the Montreal Neurological Institute and Hospital – The Neuro- at McGill University, was published in this week’s issue of the Proceedings of the National Academy of Sciences of the USA (PNAS). Continue reading

How do we split our attention?

Dr. Julio Martinez-Trujillo

DEC. 21, 2011 – McGill’s Cognitive Neurophysiology Lab team finds that we are natural-born multi-taskers

Imagine you’re a hockey goalie, and two opposing players are breaking in alone on you, passing the puck back and forth. You’re aware of the linesman skating in on your left, but pay him no mind. Your focus is on the puck and the two approaching players. As the action unfolds, how is your brain processing this intense moment of “multi-tasking”? Continue reading

A breakthrough in pinpointing protective mechanisms in Multiple Sclerosis

Alexandre Prat

December 1st, 2011 – In an article published today in the prestigious journal Science, a team of researchers led by Dr Alexander Prat and postgraduate fellow Jorge Alvarez at the University of Montreal Hospital Research Centre (CRCHUM) sheds light on how the blood-brain-barrier (BBB) works to prevent the incursion of the immune system into the brain. Continue reading

Researchers from Université Laval affiliated CHUQ discover a new therapeutic target for Lou Gehrig’s disease

Jean-Pierre Julien

November 14, 2011. – A research team from Université Laval, led by Jean-Pierre Julien, has taken a new step in understanding the cellular mechanisms involved in Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis (ALS). This disease is characterized by degeneration of neurons that control muscle activity. Continue reading

Scientists Highlight Link Between Stress and Appetite

Pittman and Bains

Researchers in the Hotchkiss Brain Institute (HBI) at the University of Calgary’s Faculty of Medicine have uncovered a mechanism by which stress increases food drive in rats. This exciting discovery, published in the journal Neuron, could provide important insight into why stress is thought to be one of the underlying contributors to obesity.

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Potential harm, but no demonstrated benefit from depression screening in primary care

Brett Thombs

September 19, 2011 – The Canadian Task Force on Preventive Health Care recommends routine screening for depression during primary care visits when systems are available for coordination of assessment and treatment. An article by an international panel of experts, published in the October issue of the Canadian Medical Association Journal, argues that there is no evidence that screening benefits patients and that, moreover, implementation of the practice would further burden an already financially-strapped health care system. Continue reading

Study exposes major flaws in research on depression screening questionnaires – Research on detection of depression “forecasting yesterday’s weather,” say investigators

Par Hendrike 11:08, 3 May 2006 (UTC) (Travail personnel) [GFDL (www.gnu.org/copyleft/fdl.html) ou CC-BY-SA-3.0 (www.creativecommons.org/licenses/by-sa/3.0/)], via Wikimedia CommonsAugust 16, 2011 – A new analysis, published in the British Medical Journal (BMJ), reports that flawed research studies have exaggerated the degree to which depression screening questionnaires are able to accurately detect people with untreated depression. The number of untreated patients who would actually be detected using these questionnaires may be less than half the number predicted by existing studies. Continue reading

Children of depressed mothers have a different brain – MRI scans show their children have an enlarged amygdala

Amygdalae - there are two in your brain

August 15, 2011 – Researchers think that brains are sensitive to the quality of child care, according to a study that was directed by Dr. Sonia Lupien and her colleagues from the University of Montreal published today in the Proceedings of the National Academy of Sciences. Continue reading