Caffeine may ease Parkinson’s symptoms

Dr. Ronald Postuma
Caffeine, which is widely consumed around the world in coffee, tea and soft drinks, may help control movement in people suffering from Parkinson’s. This is the finding of a study conducted at the Research Institute of the McGill University Health Centre (RI MUHC) that was recently published in Neurology®, the official journal of the American Academy of Neurology. The study opens the door to new treatment options for Parkinson’s disease that affects approximately 100 000 Canadians. Continue reading

Finding may suggest new treatments for sleep disorders

John Peever Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 18 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

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Widely prescribed MS treatment may not slow progression of disease: Vancouver Coastal Health and UBC Research

Dr Helen Tremlett
Dr. Helen Tremlett

Researchers with the UBC Hospital MS Clinic and Brain Research Centre at Vancouver Coastal Health and the University of British Columbia have published important data in the Journal of the American Medical Association (JAMA) about the impact of a common drug therapy on the progression of multiple sclerosis for people with the relapsing-remitting form of the disease.

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Brain scans detect early signs of autism

Dr. Alan Evans

A new study shows significant differences in brain development in high-risk infants who develop autism starting as early as age 6 months. The findings published in the American Journal of Psychiatry reveal that this abnormal brain development may be detected before the appearance of autism symptoms in an infant’s first year of life. Autism is typically diagnosed around the age of 2 or 3. Continue reading

McGill researchers discover the cause of an inherited form of epilepsy

Dr. Gary Brouhard

Findings could open avenues for improved therapies for a range of conditions

Researchers at McGill University have discovered the cause of an inherited form of epilepsy. The disease, known as double-cortex syndrome, primarily affects females and arises from mutations on a gene located on the X chromosome. Continue reading

Multiple sclerosis patients have lower risk of cancer: UBC-VCH research

Dr. Ellen Kingwell

Multiple sclerosis (MS) patients appear to have a lower cancer risk, according to a new study led by researchers at the University of British Columbia and Vancouver Coastal Health.

The study, published online in the journal Brain, is the first to investigate overall cancer risk in MS patients in North America. Continue reading

The Mammalian Methylome: Investigating how cells regulate gene expression in the brain

Dr. Cathy Barr

In developing humans and other mammals, not all genes are created equal – or equally used. The expression of certain genes, known as imprinted genes, is determined by just one copy of the parents’ genetic contribution. In humans, there are at least 80 known imprinted genes. If a copy of an imprinted gene fails to function correctly – or if both copies are expressed – the result can be a variety of heritable conditions, such as Prader-Willi and Angelman syndromes, or increased risk for cancer. Continue reading

Scientists start explaining Fat Bastard’s vicious cycle

Stephanie Fulton
Stephanie Fulton

May 24, 2012 -Fat Bastard’s revelation “I eat because I’m depressed and I’m depressed because I eat” in the Austin Powers film series may be explained by sophisticated neuroscience research being undertaken by scientists affiliated with the University of Montreal Hospital Research Centre (CRCHUM) and the university’s Faculty of Medicine. Continue reading

Discovery of a gene that causes Joubert Syndrome in the population of the Lower St. Lawrence region of Quebec

Jacques Michaud
May 10, 2012 – C5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. This is what a study in the April issue of The American Journal of Human Genetics reveals. The study was conducted by researchers from the Sainte-Justine University Hospital Research Center and the Centre of Excellence in Neuromics of Université de Montréal’s (CENUM). Continue reading