Satellite 4: Neural stem cells in development and adulthood

Date: May 13 2018, 8:30 am to 4:30 pm

Venue: Sheraton Wall Centre Vancouver

The objective of this satellite event is to bring together experts and trainees in the field of neural stem cells (NSC). The scientists working on embryonic and adult NSC will discuss recent advances in the field and bring new insights on fundamental mechanisms controlling physiology and function of these cells. The speakers will provide different perspectives on the role of NSC during brain development and in adulthood, and how these cells can be reactivated during aging or after different pathological conditions. The meeting will be a great platform to exchange ideas and develop novel collaborative projects.

Organizers:

  1. Armen Saghatelyan (Université Laval)
  2. David Kaplan (Hospital for Sick Children)
  3. Freda Miller (Hospital for Sick Children)

Event Agenda:

8h30: Arrival and Registration

9h00 Opening remarks Armen Saghatelyan (CERVO Brain Research Center)

Session 1: Embryonic neurogenesis | Chair: Michel Cayouette (Institut de recherches cliniques de Montréal)

  • 9h10 Derek van der Kooy (University of Toronto)
    Primitive and definitive neural stem cells generate different types of neural progenitor cells
  • 9h40 Carol Schuurmans (Sunnybrook Research Institute)
    Maintaining embryonic neural stem cell quiescence via a proneural gene based toggle switch
  • 10h10 Michel Cayouette (Institut de recherches cliniques de Montréal)
    Transcriptional regulation of cone photoreceptor production in the developing retina

10h40 coffee break

Session 2: Adult neurogenesis | Chair: Armen Saghatelyan (CERVO Brain Research Center)

  • 11h00 Karl Fernandes (Université de Montréal)
    Biological properties of dormant neural stem cells revealed by genetic targeting in the adult murine brain
  • 12h00 Armen Saghatelyan (CERVO Brain Research Center)
    The role of Ca2+ transients in the regulation of adult neural stem cells activity

12h30 lunch (included with registration : Burrard Room, Century Plaza Hotel, 1015 Burrard Street)

Session 3: Functional implication of adult NSCs and their activation for neural repair | Chair: Freda Miller (The Hospital for Sick Children)

  • 14h00 David Kaplan (The Hospital for Sick Children)
    Revitalizing the aging neural stem cell niche
  • 14h30 Paul Frankland (The Hospital for Sick Children)
    Hippocampal neurogenesis and forgetting

15h00 coffee break

  • 15h15 Jing Wang (Ottawa Hospital Research Institute)
    Epigenetic Regulation of Lipid Metabolism in determining adult neural stem cell fate
  • 15h35 Cindi Morshead (University of Toronto)
    Activating endogenous stem cells for neural repair
  • 16h05 Donald Mabbott (The Hospital for Sick Children)
    Metformin results in hippocampal remodeling and improved memory encoding in paediatric brain tumor survivors treated with cranial radiation: A pilot randomized controlled crossover study

16h25 Closing remarks David Kaplan, Freda Miller, Armen Saghatelyan

Registration:

Registration will be available through the CAN main meeting registration page.  Registration costs is 50$ if combined with registration to the main CAN meeting, and 75$ if you register for the NSC satellite only.

Register for the meeting and satellite here:
https://www.confmanager.com/main.cfm?cid=2601&tid=32

Register for the satellite only here:
https://www.confmanager.com/main.cfm?cid=2845&tid=32

Sponsors:

CERVO Brain Research Center

SickKids Neurosciences and Mental Health Program