The cellular secret of how memories are made, and lost

Dr. Sheena Josselyn - Photo credit: SickKid news

Dr. Sheena Josselyn

From: SickKids news

Scientists use a peptide to strengthen connections between brain cells and restore memory in a pre-clinical model.

Research led at The Hospital for Sick Children (SickKids) is illuminating the mechanism underlying memory, which could result in future therapeutic targets for conditions such as Alzheimer’s disease and dementia. 

Alzheimer’s disease is a condition that causes memory loss, characterized by the accumulation of a protein, called A-beta, in the brain that damages neurons and their connections.

Published in Nature Neuroscience, Drs. Paul Frankland and Sheena Josselyn, Senior Scientists in the Neurosciences & Mental Health program, used a peptide to block adverse effects of the accumulation of A-beta in pre-clinical models – a technique that showed promise in restoring memory.

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Read our submission to pre-budget consultations

The House of Commons Standing Committee on Finance invited Canadians to participate in its annual pre-budget consultations process. The committee will table a report on these consultations in the House of Commons with recommendations to be considered by the Deputy Prime Minister and Minister of Finance in the development of the 2025 federal budget.

Read CAN’s submission to these consultations here:

Read CAN Connection – June 2024

The Brain Prize call for nominations: now open

Brain Prize Call for nominations

The Brain Prize is currently the world’s largest prize for neuroscience and is awarded each year by the Lundbeck Foundation. The Brain Prize is awarded to one or more individuals who have distinguished themselves by making outstanding contributions in any area of neuroscience- from basic to clinical, and since it was first awarded in 2011 The Brain Prize has recognised 47 scientists from 10 different countries. You can find out more about The Brain Prize here.

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Congratulations to the winners of the 2023 CAN- CIHR-INMHA Brain Star Awards!

The Canadian Association for Neuroscience (CAN) and the Canadian Institutes of Health’s Institute of Neurosciences, Mental Health and Addiction (CIHR-INMHA) are proud to announce the winners of the 2023 Brain Star Awards.

The CIHR-INMHA Brain Star awards, administered by the Canadian Association for Neuroscience, are awarded to students and trainees who have published high impact discoveries in all fields and disciplines covered by CIHR’s Institute of Neurosciences, Mental Health and Addiction in the 2023 calendar year.

The top 3 Brain Star Award winners of the year have been invited to make a presentation at the CAN meeting in May.