Programme 2023

Programme préliminaire, sujet à modification
Congrès CAN2023 – Hotel Bonaventure Montréal

Samedi 27 mai 2023

Conférences publiques de l’ACN

Satellite meeting: Canadian Cerebellar Research Network

Jour 1: Dimanche 28 mai, 2023

9:00 -16:00	Symposiums satellites 8th Annual Canadian Neurometabolic Meeting Future Leaders in Canadian Brain Research Knowledge Exchange Neural Stem Cells function and dysfunction
17:00 – 17:15	Message de bienvenue du président Keith Murai
17:15 – 18:15	Conférence présidentielle Flora Vaccarino, Yale School of Medicine
18:15 – 20:00	Cocktail d’ouverture

Jour 2: Lundi, 29 mai 2023

8:30 – 10:15 AM	Plenary symposium 1 Gut feelings: Peripheral and central regulation of motivational and affective states by gut signals Chair: Alfonso Abizaid \| Carleton University Speakers: Keith Sharkey \| University of Calgary How the gut changes behaviour in intestinal inflammation Jane Foster \| McMaster University Microbes and Mental Health: Translating preclinical findings to the clinic Alfonso Abizaid \| Carleton University Ghrelin-endocannabinoid system interactions in the VTA in the regulation of food reward
10:15 – 10:30	CIHR-INMHA Update Sam Weiss
10:30 – 10:45	Coffee break Posters/exhibits
10:45 – 11:45	Featured Plenary speaker Dana Small \| Yale University The wisdom of the body
11:45 – 12:00	Brain Star Award presentation 1
12:00 – 1:30	Advocacy lunch, organized by the CAN Advocacy committee Stronger together – building capacity for a Brain Moonshot in Canada
1:30 – 3:00	Parallel Symposium 1: White Matter matters: the role of myelin in cognition Chair: Meira Machado \| Western University Speakers Jérémie Lefebvre \| University of Ottawa Learning to be on time: How white matter plasticity shapes brain dynamics and function Kendra Furber \| University of Northern British Columbia Myelination in the aging mouse brain Olamide Adebiyi \| Robarts Research Institute Remyelinating potentials of stigmasterol in vanadium-induced neurotoxicity and cognitive impairments Elizabeth Dao \| University of British Columbia Myelin in aging and cognitive impairment Parallel Symposium 2: Neural mechanisms of skilled motor control across species, circuits, and behaviors Chair: J. Andrew Pruszynski \| Western University Speakers: Ariel Levine \| National Institutes of Health Cell Types and Networks for Spinal Motor Control Andrew Pruszynski \| Western University Somatosensory predictions are directly embedded in neural activity that controls movement Chethan Pandarinath \| Emory University and Georgia Tech Dynamical mechanisms of flexible pattern generation in spinal neural populations Alice Mosberger \| Columbia University Learning and refining skilled actions in the basal ganglia forelimb circuitry Parallel Symposium 3: New approaches for human stem cell models of neurological disorders reveal mechanisms and therapeutic strategies Chair: Gary Bassell \| Emory University Karun Singh \| University of Toronto Investigating neural circuitry abnormalities at cellular resolution in human 3D organoid models of brain development disorders Nisha Raj \| Emory University Altered proteostasis in fragile X syndrome and other neuropsychiatric disorders Ryan Purcell \| Emory University Identifying the neurodevelopmental impact of the 3q29 deletion through single-cell sequencing Anne Bang \| Sanford Burnham, CA Drug Screens of Human Induced Pluripotent Stem Cell (hiPSC) Derived Neuronal Networks On Multi-Electrode Arrays Parallel symposium 4: Form dictates function: crosstalk between channels, scaffolds, and the cytoskeleton with implications for nervous system development and disease Co-Chairs: Leigh Anne Swayne \| University of Victoria & R Anne McKinney \| McGill University Speakers Kota Mizumoto \| The University of British Columbia UNC-9/Innexin locally inhibits chemical synapse formation independent of its channel activity in C. elegans Andrew K. J. Boyce \| University of Calgary Cytoskeletal rearrangement promotes neuroprotection following excitotoxicity at peripheral dendrites R Anne McKinney \| McGill University Synaptopodin, an actin-associated protein, is required for long-term depression Leigh Anne Swayne \| University of Victoria Pannexin 1 regulates spine stabilization by sequestering spine cytoskeletal regulators
3:00 – 5:00PM	Coffee break (3:00 – 3:30PM) Poster session 1 / exhibits
5:00 – 5:30	New investigator award lecture 1
5:30 – 6:00	New investigator award lecture 2
6:00 – 7:00	Brain Prize lecture: Ole Kiehn, University of Copenhagen Brainstem circuits for locomotion in the healthy and diseased brain
7:30 – 9:30	CAN Student Social

Jour 3: Mardi, 30 mai 2023

8:30 – 10:15 AM	Plenary symposium 2 Neuroimmune interactions: when the immune system shapes the Central Nervous System Chair: Nathalie Arbour \| Université de Montréal Speakers: Nader Ghasemlou \| Queen’s University Rhythms of neuroinflammation and chronic pain in EAE: what’s time got to do with it? Catherine Larochelle \| Université de Montréal Molecular mechanisms underlying T cell-oligodendrocytes direct interactions Veronique Miron \| University of Toronto Glial interactions regulating myelin health
10:15 – 10:30	(Brief partner updates)
10:30 – 10:45	Coffee break Posters/exhibits
10:45 – 11:45	Featured Plenary speaker 2 Maja Jagodic \| Karolinska Institutet Deciphering mechanisms of Multiple Sclerosis development and progression
11:45 – 12:00	Brain Star Award presentation 2
12:00 – 1:00	Lunch on own
1:00 – 2:30	Parallel Symposium 5 Interactions between diet and cognition Chair: Léa Décarie-Spain \| University of Southern California Co-sponsored the Société des Neurosciences and the Canadian Association for Neuroscience Speakers: Léa Décarie-Spain \| University of Southern California Trapping a meal engram in the hippocampus Guillaume Ferreira \| Université de Bordeaux Obesogenic diet induces circuit-specific memory deficits Vivien Chevaleyre \| Institute of Psychiatry and Neuroscience of Paris How an obesogenic high-fat diet disrupts oxytocinergic signaling in hippocampal area CA2 and social memory formation Stephanie Borgland \| University of Calgary Time dependent changes in the orbitofrontal cortex with exposure to an obesogenic diet. Parallel Symposium 6 Synaptic, molecular and ultrastructural dynamics during learning Co-Chairs : Flavie Lavoie-Cardinal \| Université Laval Jean-Claude Béïque \| University of Ottawa Speakers : Flavie Lavoie-Cardinal \| Université Laval Machine learning-assisted super-resolution microscopy at synapses Jean-Claude Béïque \| University of Ottawa Nature and dynamics of synaptic eligibility traces in cortex Aparna Suvrathan\| McGill University Heterogeneity in information processing by cerebellar synapses Shernaz Bamji \| University of British Columbia Role of posttranslational palmitoylation in synaptic plasticity Parallel Symposium 7 Adolescent Stress Sensitivity and Modulation of Behaviour Across the Lifespan Chair: Maithe Arruda Carvalho \| University of Toronto Scarborough Speakers: Maithe Arruda-Carvalho \| University of Toronto Scarborough Synaptic maturation of affective learning circuits Deena Walker \| Oregon Health and Science University Adolescent social isolation disrupts sex-specific developmental profiles of GABA- and glutamatergic gene expression throughout the reward circuitry Tamara Franklin \| Dalhousie University The long-term and intergenerational effects of adolescent stress Heidi Meyer \| Boston University Developmental age and sex interact to scale the effects of stress on fear regulation Parallel Symposium 8 Protein Synthesis in Brain Health and Disease Chair: Jesper Sjöström \| McGill University Presenters: Hovy Ho-Wai Wong \| McGill University Local protein synthesis in axons sustains synapse-specific neurotransmission Cyril Hanus \| University of Paris Impact of dendritic processing on synaptic receptor glycosylation and function Ning Cheng \| University of Calgary Targeting ERK signaling to treat Fragile X Syndrome and autism Barbara Bardoni \| Université Côte d’Azur RNA metabolism and pathophysiology of brain developmental disorders: Fragile X Messenger Ribonucleoprotein (FMRP) as a paradigmatic factor
2:30 – 4:30	2:30 – 3:00 Coffee break in Poster Hall 2:30 – 4:30 Poster session 2 & Exhibits
4:30 – 4:45	Honor for Karim Nader
4:45– 5:45	Keynote Lecture Sheena Josselyn, SickKids Hospital Making memories in mice
5:45 – 6:45	Life and Neuroscience Panel discussion with Sheena Josselyn, Ole Kiehn, Flora Vaccarino, Maja Jagodic, Hugo Bellen, Dana Small

Jour 4: Mercredi 31 mai 2023

8:30 – 10:15 A.M.	Plenary symposium 3 Emerging molecular mechanisms of neurodegeneration Chair: Maria Ioannou Speakers: Heidi McBride \| McGill University Immune signaling in Parkinson’s Disease: perspectives of a mitochondria Karl Fernandes \| Université de Sherbrooke Fatty acid desaturation: an unexpected role in the pathophysiology of Alzheimer’s disease Maria Ioannou \| University of Alberta Protecting neurons from degeneration by autolysosomal exocytosis
10:15 – 10:30	Overview of BrightFocus Foundation opportunities Diane Bovenkamp, PhD Vice President, Scientific Affairs, BrightFocus Foundation
10:30 – 10:45	Posters/exhibits Coffee break
10:45 – 11:45	Featured Plenary speaker Hugo Bellen – Baylor College of Medicine Lipid droplets in Alzheimer’s Disease
11:45 – 12:00 PM	Brain Star Award presentation 3
12:00 – 1:30 PM	CAN-ACN Annual General Meeting of members Career Networking event Lunch on own
1:30 – 3:30	Poster session 3 & Exhibits
3:30 – 5:00	Parallel Symposium 9 Cross-disciplinary neuroscience perspectives on autism spectrum disorder Chair: Argel Aguilar Valles \| Carleton University Speakers Emma Duerden \| Western University Amygdala subnuclei maturation and the association with anxiety in children and youth with autism spectrum disorder Melissa Perreault \| University of Guelph Sex considerations in translational ASD research Tabrez Siddiqui \| University of Manitoba Molecular logic of circuit organization by autism-associated synaptic adhesion proteins Eric Klann \| New York University Autism-related mutations in EEF1A2 alter translation and actin bundling Parallel Symposium 10 Cannabinoids, Endocannabinoids and Microglia Chairs: Haley Vecchiarelli \| University of Victoria & Marie-Ève Tremblay \| University of Victoria Speakers: Mallar Chakravarty \| McGill University The impact of prenatal delta-9-tetrahydrocannabinol on the brain and behaviour development across the lifespan Haley Vecchiarelli \| University of Victoria Effect of acute vapourized cannabis on microglia Tuan Trang \| University of Calgary Central actions of cannabis in neuropathic pain Cecilia Hillard \| Medical College of Wisconsin Role of microglial CB2 receptors in the locomotor effects of cocaine Parallel Symposium 11 Cerebellar wiring and vulnerability in health and disease Chair: Julie Lefebvre \| The Hospital for Sick Children Speakers: Julie L Lefebvre \| The Hospital for Sick Children Regulation of inhibitory interneuron wiring in the cerebellum by an atypical Cadherin James P Fawcett \| Dalhousie University Fundamental mechanism in interneuron synaptic organization and function Sophie Tremblay \| Université de Montréal Modulation of microglia responses to prevent cerebellar injury and function Jeehye Park \| The Hospital for Sick Children Investigation of cerebellar pathology in MATR3 S85C knock-in mouse model of ALS Parallel Symposia 12 Brain wide network mapping in mice and its applications Chair: Anne Wheeler \| The Hospital for Sick Children Speakers: Timothy Murphy \| University of British Columbia Wide field single photon cortical imaging in combination with sub-cortical or cerebellar neuropixel or fiber photometry Sophie Pezet \| ESPCI Paris Identification of specific cerebral networks functionally altered during neuropathic pain in awake mice, using ultrafast ultrasound imaging Gisella Vetere \| École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris Memory networks in mice Anne Wheeler \| The Hospital for Sick Children Disruption of white matter maturation and its impact on brain-wide networks and behaviour