| Abstract No.: | B-D2137 |
| Country: | Canada |
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| Title: | MODULATION OF DEPTH PERCEPTION WITH TRANSCRANIAL MAGNETIC STIMULATION OF HUMAN AREA V2/V3 |
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| Authors/Affiliations: | 1 Michael Waterston*; 1 Christopher Pack ;
1 Montreal Neurological Institute, McGill University, QC, Canada
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| Content: | Recent studies in both humans and monkeys have suggested that visual area V3/V3A contributes to the perception of depth based on binocular disparity; however change in function due to intervention in this area has not been demonstrated. We examined the impact of TMS on human depth perception by using fMRI of retinotopically-organized areas to locate the target cortical region. A random dot stereogram, gradually increasing in disparity, was presented until the subject perceived it as being nearer or farther than the fixation plane. The threshold disparity for perceiving depth was measured for different locations in the visual field before, during, and after the application of rTMS. We found a significant modulation of the disparity threshold for depth perception following TMS and dependent on the frequency of stimulation. This result establishes a link between depth perception and neuronal activity in human areas V2 and V3. It also reinforces TMS as a valuable tool for validating the contribution of cortical areas to visual perception in humans. |
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