| Abstract No.: | A-G1191 |
| Country: | Canada |
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| Title: | GENETIC SCREEN FOR GENES INVOLVED IN AGGRESSION IN DROSOPHILA MELANOGASTER |
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| Authors/Affiliations: | 2 Songting Cheng*; 1 Yi Rao; 2 Yong Rao;
1 Beijing, China; 2 Center for Research in Neuroscience, Montreal, QC, Canada.
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| Content: | Aggression is a complex social behavior that is poorly understood at the molecular level. To identify novel genes involved in the control of aggressive behaviors, we perform genetic screen to examine if knocking down the expression of G protein coupling receptors (GPCRs) and neuropeptides affects the fly aggression. It has been shown that GPCRs and neuropeptides play important roles in a variety of Drosophila behaviors. Gene knockdown was performed specifically at adult stage, which allows the analysis of the in vivo function of GPCRs and neuropeptides specifically in the adult nervous system. We show that aggression behavior is measurable in fly. The result of the genetic screen will be presented at the meeting. We believe this screen will provide novel and important insights into the molecular mechanism of aggression. |
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