| Abstract No.: | A-C1100 |
| Country: | Canada |
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| Title: | TRANSCRANIAL MAGNETIC STIMULATION EFFECT ON PARKINSON MOTOR FUNCTION– META ANALYSIS OF CONTROLLED TRIALS |
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| Authors/Affiliations: | 2 Behzad Elahi*; 1 Behrad Elahi; 2 Robert Chen;
1 Iran Medical School, Tehran, Iran; 2 University of Toronto, ON, Canada
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| Content: | Objective: The aim of this study was to evaluate and collect current evidence on the effect of Transcranial Magnetic Stimulation (TMS) in motor improvement in Parkinson Disease.
Method: The Medline, Embase, CINAHL, Web of Science, Scopus bibliographic, and Google Scholar databases were searched and articles published between January 1985 and October 2007, and relevant controlled clinical trials were extracted, reviewed, and validated according to the study protocol. The outcome of interest was Unified Parkinson’s Disease Rating Scale (UPDRS).
Results: ten randomized, controlled clinical trials were included in the meta-analysis. Pooling of the results from these trials yielded an effect size -0.68 with a 95% CI for high frequency TMS studies and none significant findings for low frequency TMS studies.
Conclusion: the benefits of high frequency TMS was confirmed by the meta-analysis; but lower frequency TMS studies had little if any effect in PD patients. |
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