Scientists have known for years that blood vessel loss in the brain impacts cognitive decline as people age. New research from the University of Victoria has provided an explanation for why we lose blood vessels—vital knowledge that could lead to better preventive and protective strategies for maintaining brain health.
UVic neuroscientist Craig Brown and PhD student Patrick Reeson have been researching the phenomenon of clogged capillaries, the brain’s smallest blood vessels. These tiny capillaries routinely get “stuck,” clogged by cells, fat and debris in the blood. Most clear within seconds to minutes, however some can remain stuck for much longer, but what ultimately happens to these lingering clogs has remained a mystery.